Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Folylpolyglutamate synthase

Gene

folC

Organism
Sulfurovum sp. (strain NBC37-1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. dihydrofolate synthase activity Source: UniProtKB-EC
  3. tetrahydrofolylpolyglutamate synthase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciSSP387093:GH25-2075-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Folylpolyglutamate synthaseImported (EC:6.3.2.12Imported, EC:6.3.2.17Imported)
Gene namesi
Name:folCImported
Ordered Locus Names:SUN_2042Imported
OrganismiSulfurovum sp. (strain NBC37-1)Imported
Taxonomic identifieri387093 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaSulfurovum
ProteomesiUP000006378 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi387093.SUN_2042.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0285.
HOGENOMiHOG000102383.
KOiK11754.
OMAiYTEIGLD.
OrthoDBiEOG6ZPSW2.

Family and domain databases

Gene3Di3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProiIPR001645. Folylpolyglutamate_synth.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
[Graphical view]
PANTHERiPTHR11136. PTHR11136. 1 hit.
PfamiPF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMiSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsiTIGR01499. folC. 1 hit.

Sequencei

Sequence statusi: Complete.

A6QBX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDLTFAEFL DKKPLYYKEI DHERVHVAYR MLKPHIDRPK TVHVVGTNGK
60 70 80 90 100
GSTGRMISHL AYQGAGLSVG HFSSPHILKF NERIWMNGSD ASDEVLEAAH
110 120 130 140 150
QKLFAILGEK MSHALSYFEY TTLLAFVVFE NCDLMVLEAG LGGEFDATNV
160 170 180 190 200
CDKELSVITP IGIDHQVFLG DSIEEIAATK IRSIQSGAKV LIAPQPYEEV
210 220 230 240 250
VEVAAQIAEK KGVEFFLSEQ KAETREQLEY VALEKSWGSY LVDNAMVALQ
260 270 280 290 300
ALDILNIPYD IEALGTLELF GRFYPLTKNI RIDVGHNPLA AKAIVGAMEP
310 320 330 340 350
DTVLIYNSLD DKDYEEVLRT LKPKVKRVEI IRIDSQRATT VKDIEAALEK
360 370 380
VGLPYSDFQN SMEDDQHYLV FGSFYTVEAF LKKLKIKN
Length:388
Mass (Da):43,612
Last modified:August 21, 2007 - v1
Checksum:i598E04D472D1FD4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009179 Genomic DNA. Translation: BAF72983.1.
RefSeqiWP_012083804.1. NC_009663.1.
YP_001359340.1. NC_009663.1.

Genome annotation databases

EnsemblBacteriaiBAF72983; BAF72983; SUN_2042.
KEGGisun:SUN_2042.
PATRICi23777141. VBISulSp49917_2081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009179 Genomic DNA. Translation: BAF72983.1.
RefSeqiWP_012083804.1. NC_009663.1.
YP_001359340.1. NC_009663.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi387093.SUN_2042.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAF72983; BAF72983; SUN_2042.
KEGGisun:SUN_2042.
PATRICi23777141. VBISulSp49917_2081.

Phylogenomic databases

eggNOGiCOG0285.
HOGENOMiHOG000102383.
KOiK11754.
OMAiYTEIGLD.
OrthoDBiEOG6ZPSW2.

Enzyme and pathway databases

BioCyciSSP387093:GH25-2075-MONOMER.

Family and domain databases

Gene3Di3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProiIPR001645. Folylpolyglutamate_synth.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
[Graphical view]
PANTHERiPTHR11136. PTHR11136. 1 hit.
PfamiPF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMiSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsiTIGR01499. folC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens."
    Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K.
    Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBC37-1Imported.

Entry informationi

Entry nameiA6QBX4_SULNB
AccessioniPrimary (citable) accession number: A6QBX4
Entry historyi
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: April 1, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.