A6Q9B0 (A6Q9B0_SULNB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid A disaccharide synthetase EMBL BAF72069.1
EC=2.4.1.182 EMBL BAF72069.1

Gene names

Name:	lpxB EMBL BAF72069.1
Ordered Locus Names:	SUN_1114

Organism

Sulfurovum sp. (strain NBC37-1) [Complete proteome] [HAMAP]

Taxonomic identifier

387093 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Sulfurovum

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL BAF72069.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6Q9B0 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: A391B88B0C232B66	FASTA	349	39,549
	10 20 30 40 50 60 MKLLVSALEP SSNLHLKEVL KHTRDIELMG IFDKSIENGT PLYDISQMAI MGVVDAVKKL 70 80 90 100 110 120 RWFFKVADEM VALAKDADKV LLMDGSGFNL PLAKKLKTTY PDKEIIYYIL PQVWASRPKR 130 140 150 160 170 180 VAKLEKYCDH LLGILPFEID YYKSGKAQYV GHPLLDEIDI EHDGERAKGY IAFMPGSRKA 190 200 210 220 230 240 EISRLMPIFL ELRQKLGSEI RPLLVIPPSF SDKKIAELYE GSDAFEIIRD THDALRRSEF 250 260 270 280 290 300 AFICSGTATL EAALIGTPFT LTYIAKKIDY FVAFKILGIT QIGLANIILS HYNGTTLHKE 310 320 330 340 LLQEEVTVDN LLKEYYNTDR KKFTAKAKEL REYLGHGSSA NVARIIMQP

References

[1]

"Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens." Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K. Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007) [PubMed: 17615243] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009179 Genomic DNA. Translation: BAF72069.1.
RefSeq	YP_001358426.1. NC_009663.1.
3D structure databases
ProteinModelPortal	A6Q9B0.
ModBase	Search...
Protein-protein interaction databases
STRING	A6Q9B0.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5364064.
GenomeReviews	Gene locus SUN_1114 in contig AP009179_GR.
KEGG	sun:SUN_1114.
NMPDR	fig|387093.4.peg.1065.
PATRIC	23775195. VBISulSp49917_1126.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	AEFAFIC.
ProtClustDB	PRK14089.
Enzyme and pathway databases
BioCyc	SSP387093:SUN_1114-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6Q9B0_SULNB

Accession

Primary (citable) accession number: A6Q9B0

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)