A6Q828 (A6Q828_SULNB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401

Gene names

Name:	msrA EMBL BAF71637.1
Synonyms:	msrA1 HAMAP MF_01401
Ordered Locus Names:	SUN_0678

Organism

Sulfurovum sp. (strain NBC37-1) [Complete proteome] [HAMAP]

Taxonomic identifier

387093 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Sulfurovum

Protein attributes

Sequence length	175 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL BAF71637.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	12	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A6Q828 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: C4304185D8D4D701	FASTA	175	19,809
	10 20 30 40 50 60 MAQKELIVGG GCFWCTEAVF ELLRGVSDVE SGYANGDVPN PDYRMICGGD TGYAEVIRIT 70 80 90 100 110 120 YDDEIIDLDT LFDVFFATHN PTTLNRQGAD EGTQYRSCIC YEDEGTLKAA KRAIERAQAD 130 140 150 160 170 YNDPIVTTLE PLRNYYPAED YHQDYYRQNP MQGYCNAVIP PKIVKLIEKF SDKVT

References

[1]

"Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens." Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K. Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007) [PubMed: 17615243] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009179 Genomic DNA. Translation: BAF71637.1.
RefSeq	YP_001357994.1. NC_009663.1.
3D structure databases
ProteinModelPortal	A6Q828.
ModBase	Search...
Protein-protein interaction databases
STRING	A6Q828.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5361905.
GenomeReviews	Gene locus SUN_0678 in contig AP009179_GR.
KEGG	sun:SUN_0678.
NMPDR	fig|387093.4.peg.664.
PATRIC	23774321. VBISulSp49917_0689.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	PYCRFVI.
Enzyme and pathway databases
BioCyc	SSP387093:SUN_0678-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6Q828_SULNB

Accession

Primary (citable) accession number: A6Q828

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)