A6Q6T5 (A6Q6T5_SULNB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Name:	trxB EMBL BAF71194.1
Ordered Locus Names:	SUN_0234

Organism

Sulfurovum sp. (strain NBC37-1) [Complete proteome] [HAMAP]

Taxonomic identifier

387093 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Sulfurovum

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880 EMBL BAF71194.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6Q6T5 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: F6D9F7AB0EA124E3	FASTA	313	34,159
	10 20 30 40 50 60 MLDCAIIGGG PAGLTAGLYA TRGGLKNVTM FEMGMPGGQI TQSSEIENYP GFFEHDKTGM 70 80 90 100 110 120 DFMDTWQKQC FHFGLKHEMK KVERIAKTGE HFTITLEGGE QVEAKTTVVC TGSVPKRAGF 130 140 150 160 170 180 KGEDEFFGKG VSTCATCDGF FYKDKPVTVL GGGDTALEEA LYLSNICSDV YVIHRRDTFR 190 200 210 220 230 240 AAPPTMERVE KKENIHLVTD SVIEEAYGDA MGLQGMKVRN IKTDEITDMK NTGLFVFVGH 250 260 270 280 290 300 DVRNEVLKDE NGGFICEMND WGQVIVDLSM RTSVEGLYAA GDLRVEAPKQ VVVAAGDGAT 310 AALQVISYIQ EQA

References

[1]

"Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens." Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K. Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007) [PubMed: 17615243] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009179 Genomic DNA. Translation: BAF71194.1.
RefSeq	YP_001357551.1. NC_009663.1.
3D structure databases
ProteinModelPortal	A6Q6T5.
SMR	A6Q6T5. Positions 1-310.
ModBase	Search...
Protein-protein interaction databases
STRING	A6Q6T5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5362488.
GenomeReviews	Gene locus SUN_0234 in contig AP009179_GR.
KEGG	sun:SUN_0234.
NMPDR	fig|387093.4.peg.228.
PATRIC	23773405. VBISulSp49917_0236.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	TNDQMET.
ProtClustDB	CLSK872456.
Enzyme and pathway databases
BioCyc	SSP387093:SUN_0234-MONOMER.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6Q6T5_SULNB

Accession

Primary (citable) accession number: A6Q6T5

Entry history

Integrated into UniProtKB/TrEMBL:	August 21, 2007
Last sequence update:	August 21, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)