A6Q1S6 (TRPF_NITSB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	NIS_0321

Organism

Nitratiruptor sp. (strain SB155-2) [Complete proteome] [HAMAP]

Taxonomic identifier

387092 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › unclassified Epsilonproteobacteria › Nitratiruptor

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000197112

Sequences

	Sequence		Length	Mass (Da)
	A6Q1S6 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: E43F3149D4198E15	FASTA	196	22,142
	10 20 30 40 50 60 MRVKICGITN LEDALVAIEA GADALGFVFY EKSPRYIHPQ EAKIISKKLP PFVERVGLFV 70 80 90 100 110 120 HEEPVKIDEI CSYCNMSLAQ IHFDVEESFF EKLQTKALPV VRAKCAEDIL QFSDRYRLVD 130 140 150 160 170 180 AYVPEFGGAG RRVALEWFEN IDCSKIVLAG GLSPKNVSEV KRYGFYGVDV SSGVEARKGK 190 KDPQKVREFI QKAKFE

References

[1]

"Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens." Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K. Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB155-2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009178 Genomic DNA. Translation: BAF69435.1.
RefSeq	YP_001355792.1. NC_009662.1.
3D structure databases
ProteinModelPortal	A6Q1S6.
ModBase	Search...
Protein-protein interaction databases
STRING	387092.NIS_0321.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAF69435; BAF69435; NIS_0321.
GeneID	5360510.
KEGG	nis:NIS_0321.
PATRIC	22682626. VBINitSp82229_0334.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	FERQAID.
ProtClustDB	CLSK922769.
Enzyme and pathway databases
BioCyc	NSP387092:GHA5-341-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI_dom. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_NITSB

Accession

Primary (citable) accession number: A6Q1S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	August 21, 2007
Last modified:	May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program