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A6Q1C2 (A6Q1C2_NITSB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase HAMAP MF_00163
Short name=PDF HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase HAMAP MF_00163
Gene names
Name:def HAMAP MF_00163 EMBL BAF69281.1
Ordered Locus Names:NIS_0166
OrganismNitratiruptor sp. (strain SB155-2) [Complete proteome] [HAMAP]
Taxonomic identifier387092 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Nitratiruptor

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1381 By similarity HAMAP MF_00163
Metal binding951Iron By similarity HAMAP MF_00163
Metal binding1371Iron By similarity HAMAP MF_00163
Metal binding1411Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A6Q1C2 [UniParc].

Last modified August 21, 2007. Version 1.
Checksum: 55087BB193063613

FASTA17620,525
        10         20         30         40         50         60 
MIRQIITYPD KRLFLRSKEV ENFDEELQTL LDDMYETMVA KNGIGLAAIQ VAVPLRALII 

        70         80         90        100        110        120 
NLPDEEGKQH KEDLLELINP VIVEKKGTQV YTEGCLSVPD YYDDVERAEW VKVEYQDRYG 

       130        140        150        160        170 
NKKTLETDGL LAVAVQHEMD HLDGHLFIEK LPYMKRKKFE KEWKKKRKTA KSGVKV

« Hide

References

[1]"Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens."
Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K.
Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007) [PubMed: 17615243] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009178 Genomic DNA. Translation: BAF69281.1.
RefSeqYP_001355638.1. NC_009662.1.

3D structure databases

ProteinModelPortalA6Q1C2.
SMRA6Q1C2. Positions 4-162.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6Q1C2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5360282.
GenomeReviewsGene locus NIS_0166 in contig AP009178_GR.
KEGGnis:NIS_0166.
PATRIC22682284. VBINitSp82229_0177.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAMINAHIE.
ProtClustDBPRK00150.

Enzyme and pathway databases

BioCycNSP387092:NIS_0166-MONOMER.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6Q1C2_NITSB
AccessionPrimary (citable) accession number: A6Q1C2
Entry history
Integrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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