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Protein
Submitted name:

Voltage-dependent L-type calcium channel subunit beta-2

Gene

CACNB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent L-type calcium channel subunit beta-2Imported
Gene namesi
Name:CACNB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000165995.18.
HGNCiHGNC:1402. CACNB2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165995.

PTM / Processingi

Proteomic databases

MaxQBiA6PVM6.
PaxDbiA6PVM6.
PeptideAtlasiA6PVM6.
PRIDEiA6PVM6.

Expressioni

Gene expression databases

BgeeiENSG00000165995.
ExpressionAtlasiA6PVM6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA6PVM6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 210GuKcInterPro annotationAdd BLAST60

Keywords - Domaini

SH3 domainSAAS annotation

Phylogenomic databases

eggNOGiKOG3812. Eukaryota.
ENOG410XRDI. LUCA.
GeneTreeiENSGT00390000002740.
HOGENOMiHOG000230979.
HOVERGENiHBG050765.

Family and domain databases

InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR027417. P-loop_NTPase.
IPR036028. SH3-like_dom_sf.
IPR000584. VDCC_L_bsu.
PANTHERiPTHR11824. PTHR11824. 2 hits.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
PF12052. VGCC_beta4Aa_N. 1 hit.
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A6PVM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRDMSKSP PTAAAAVAQE IQMELLENVA PAGALGAAAQ SYGKGARRKN
60 70 80 90 100
RFKGSDGSTS SDTTSNSFVR QGSADSYTSR PSDSDVSLEE DREAVRREAE
110 120 130 140 150
RQAQAQLEKA KTKPVAFAVR TNVSYSAAHE DDVPVPGMAI SFEAKDFLHV
160 170 180 190 200
KEVLQRLIKS RGKSQAKHLN VQMVAADKLA QCPPELFDVI LDENQLEDAC
210 220 230 240 250
EHLADYLEAY WKATHPPSSS LPNPLLSRTL ATSSLPLSPT LASNSQGSQG
260 270 280 290 300
DQRTDRSAPI RSASQAEEEP SVEPVKKSQH RSSSSAPHHN HRSGTSRGLS
310 320 330 340 350
RQETFDSETQ ESRDSAYVEP KEDYSHDHVD HYASHRDHNH RDETHGSSDH
360 370 380 390 400
RHRESRHRSR DVDREQDHNE CNKQRSRHKS KDRYCEKDGE VISKKRNEAG
410
EWNRDVYIRQ
Length:410
Mass (Da):45,838
Last modified:August 21, 2007 - v1
Checksum:iBF2F605E83F8EA09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139814 Genomic DNA. No translation available.
AL353603 Genomic DNA. No translation available.
AL360231 Genomic DNA. No translation available.
AL390783 Genomic DNA. No translation available.
AL450364 Genomic DNA. No translation available.
AL450384 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000377328; ENSP00000366545; ENSG00000165995.
UCSCiuc009xjz.2. human.

Similar proteinsi

Entry informationi

Entry nameiA6PVM6_HUMAN
AccessioniPrimary (citable) accession number: A6PVM6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: November 22, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported