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Protein
Submitted name:

Plasminogen

Gene

PLG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

  • protein domain specific binding Source: AgBase
  • signaling receptor binding Source: AgBase

Names & Taxonomyi

Protein namesi
Submitted name:
PlasminogenImported
Gene namesi
Name:PLGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000122194.18
HGNCiHGNC:9071 PLG

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000122194

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500270058620 – 166Sequence analysisAdd BLAST147

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiA6PVI2
PRIDEiA6PVI2

Expressioni

Gene expression databases

BgeeiENSG00000122194
ExpressionAtlasiA6PVI2 baseline and differential

Interactioni

GO - Molecular functioni

  • protein domain specific binding Source: AgBase
  • signaling receptor binding Source: AgBase

Structurei

3D structure databases

ProteinModelPortaliA6PVI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 166KringleInterPro annotationAdd BLAST48

Keywords - Domaini

KringlePROSITE-ProRule annotationSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119133
HOGENOMiHOG000115578
HOVERGENiHBG003051

Family and domain databases

Gene3Di2.40.20.10, 1 hit
InterProiView protein in InterPro
IPR000001 Kringle
IPR013806 Kringle-like
IPR038178 Kringle_sf
IPR003609 Pan_app
PfamiView protein in Pfam
PF00051 Kringle, 1 hit
PF00024 PAN_1, 1 hit
SMARTiView protein in SMART
SM00130 KR, 1 hit
SM00473 PAN_AP, 1 hit
SUPFAMiSSF57440 SSF57440, 1 hit
PROSITEiView protein in PROSITE
PS50070 KRINGLE_2, 1 hit

Sequencei

Sequence statusi: Fragment.

A6PVI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHKEVVLLL LLFLKSGQGE PLDDYVNTQG ASLFSVTKKQ LGAGSIEECA
60 70 80 90 100
AKCEEDEEFT CRYFHCRCTY AGICNSDGKA FQYHSKEQQC VIMAENRKSS
110 120 130 140 150
IIIRMRDVVL FEKKVYLSEC KTGNGKNYRG TMSKTKNGIT CQKWSSTSPH
160
RPRFSPATHP SEGLEE
Length:166
Mass (Da):18,746
Last modified:August 21, 2007 - v1
Checksum:i770E0B6C22E1A86E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei166Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109933 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000418964; ENSP00000389424; ENSG00000122194
UCSCiuc063srd.1 human

Entry informationi

Entry nameiA6PVI2_HUMAN
AccessioniPrimary (citable) accession number: A6PVI2
Entry historyiIntegrated into UniProtKB/TrEMBL: August 21, 2007
Last sequence update: August 21, 2007
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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