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Protein
Submitted name:

Fibronectin type 3 and ankyrin repeat domains protein 1

Gene

FANK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Fibronectin type 3 and ankyrin repeat domains protein 1Imported
Gene namesi
Name:FANK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:23527. FANK1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203780.

PTM / Processingi

Proteomic databases

PeptideAtlasiA6NP17.
PRIDEiA6NP17.

Expressioni

Gene expression databases

BgeeiENSG00000203780.
ExpressionAtlasiA6NP17. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA6NP17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 101Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini114 – 261ANK_REP_REGIONInterPro annotationAdd BLAST148
Repeati154 – 186ANKPROSITE-ProRule annotationAdd BLAST33
Repeati187 – 219ANKPROSITE-ProRule annotationAdd BLAST33
Repeati221 – 254ANKPROSITE-ProRule annotationAdd BLAST34

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00880000137874.
HOGENOMiHOG000293255.
HOVERGENiHBG051552.

Family and domain databases

CDDicd00204. ANK. 1 hit.
cd00063. FN3. 1 hit.
Gene3Di1.25.40.20. 3 hits.
2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 4 hits.
SM00060. FN3. 1 hit.
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
PS50853. FN3. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NP17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPSKPHPPV VGKVTHHSIE LYWDLEKKAK RQGPQEQWFR FSIEEEDPKM
60 70 80 90 100
HTYGIIYTGY ATKHVVEGLE PRTLYRFRLK VTSPSGECEY SPLVSVSTTS
110 120 130 140 150
SIWLGGEPIS SEHLHRAVSV NDEDLLVRIL QGGRVKVDVP NKFGFTALMV
160 170 180 190 200
AAQKGYTSLM LACYAGHLDV VKYLRRHGAS WQARDLGGCT ALHWAADGGH
210 220 230 240 250
CSVIEWMIKD GCEVDVVDTG SGWTPLMRVS AVSGNQRVAS LLIDAGANVN
260 270 280
VKDRNGKTPL MSVVSLLEER KKKQRPKKSC VC
Length:282
Mass (Da):31,313
Last modified:July 24, 2007 - v1
Checksum:i8177CD70C6D045FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063963 Genomic DNA. No translation available.
AL360176 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000368691; ENSP00000357680; ENSG00000203780.
UCSCiuc057wtd.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA6NP17_HUMAN
AccessioniPrimary (citable) accession number: A6NP17
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: July 5, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported