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Protein

Sentan

Gene

SNTN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.By similarity

Miscellaneous

'Sentan' means 'tip' in Japanese.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Sentan
Alternative name(s):
Protein S100-A1-like
S100 calcium-binding protein A1-like
Gene namesi
Name:SNTN
Synonyms:S100A1L
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000188817.7.
HGNCiHGNC:33706. SNTN.
neXtProtiNX_A6NMZ2.

Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cilium

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188817.
PharmGKBiPA164726205.

Polymorphism and mutation databases

BioMutaiSNTN.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003425161 – 147SentanAdd BLAST147

Proteomic databases

PaxDbiA6NMZ2.
PRIDEiA6NMZ2.

PTM databases

iPTMnetiA6NMZ2.
PhosphoSitePlusiA6NMZ2.

Expressioni

Gene expression databases

BgeeiENSG00000188817.
ExpressionAtlasiA6NMZ2. baseline and differential.
GenevisibleiA6NMZ2. HS.

Organism-specific databases

HPAiHPA043322.
HPA058399.

Structurei

3D structure databases

ProteinModelPortaliA6NMZ2.
SMRiA6NMZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the S-100 family.Curated

Phylogenomic databases

eggNOGiENOG410IX65. Eukaryota.
ENOG41116AU. LUCA.
GeneTreeiENSGT00390000003322.
HOGENOMiHOG000154359.
InParanoidiA6NMZ2.
PhylomeDBiA6NMZ2.
TreeFamiTF335855.

Family and domain databases

CDDicd00213. S-100. 1 hit.
InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR034325. S-100_dom.
IPR013787. S100_Ca-bd_sub.
IPR026790. Sentan.
PANTHERiPTHR11639:SF24. PTHR11639:SF24. 1 hit.
SMARTiView protein in SMART
SM01394. S_100. 1 hit.
SUPFAMiSSF47473. SSF47473. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NMZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGCMHSTQD KSLHLEGDPN PSAAPTSTCA PRKMPKRISI SKQLASVKAL
60 70 80 90 100
RKCSDLEKAI ATTALIFRNS SDSDGKLEKA IAKDLLQTQF RNFAEGQETK
110 120 130 140
PKYREILSEL DEHTENKLDF EDFMILLLSI TVMSDLLQNI RNVKIMK
Length:147
Mass (Da):16,468
Last modified:July 24, 2007 - v1
Checksum:iF1813E10E7BA5D13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CD690073 mRNA. No translation available.
AC136289 Genomic DNA. No translation available.
BR000723 mRNA. Translation: FAA00429.1.
CCDSiCCDS33779.1.
RefSeqiNP_001074006.1. NM_001080537.1.
UniGeneiHs.130704.

Genome annotation databases

EnsembliENST00000343837; ENSP00000341442; ENSG00000188817.
GeneIDi132203.
KEGGihsa:132203.
UCSCiuc003dlr.4. human.

Similar proteinsi

Entry informationi

Entry nameiSNTAN_HUMAN
AccessioniPrimary (citable) accession number: A6NMZ2
Secondary accession number(s): B7FF65
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: July 24, 2007
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families