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A6NMN3 (F170B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative protein FAM170B
Gene names
Name:FAM170B
Synonyms:C10orf73
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the FAM170 family.

Sequence caution

The sequence AAH29839.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAH47597.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Putative protein FAM170B
PRO_0000310494

Natural variations

Natural variant691R → L.
Corresponds to variant rs17773851 [ dbSNP | Ensembl ].
VAR_037062

Experimental info

Sequence conflict841S → F in AAH29839. Ref.2

Sequences

Sequence LengthMass (Da)Tools
A6NMN3 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 4DEE3A62AF7BE9DF

FASTA28332,092
        10         20         30         40         50         60 
MKCYFTDHRG EQSPTDGTTL SLTSPESTEE SVEVFWPGTI QREGSSPRPG PAIPREEGLY 

        70         80         90        100        110        120 
FAARDRGMRD WSSSPSSESS EYQSYSQYQS CCSCMCDEDN AAPQSVCAFY THVQTVRGVA 

       130        140        150        160        170        180 
VAWETEAGFE PVTRKPRIHE AQFIKRQRWN GSSFEMASNT DMRWDLEACK SNCSPEPEDI 

       190        200        210        220        230        240 
DLLECCLQEL REPPDWLVTT NYGVRCVACC RVLPSLDALL EHAQHGIREG FSCQIFFEEM 

       250        260        270        280 
LERRRAQGQA HDQQLEEEQS PSDNSECSRP QGEVLSAQQQ EKQ 

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain and Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC084727 Genomic DNA. No translation available.
BC029839 mRNA. Translation: AAH29839.1. Different initiation.
BC047597 mRNA. Translation: AAH47597.1. Different initiation.
RefSeqNP_001157956.1. NM_001164484.1.
UniGeneHs.646291.

3D structure databases

ProteinModelPortalA6NMN3.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteA6NMN3.

Proteomic databases

PaxDbA6NMN3.
PRIDEA6NMN3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000311787; ENSP00000308292; ENSG00000172538.
GeneID170370.
KEGGhsa:170370.
UCSCuc001jhj.3. human.

Organism-specific databases

CTD170370.
GeneCardsGC10M050339.
HGNCHGNC:19736. FAM170B.
HPAHPA043899.
HPA050610.
neXtProtNX_A6NMN3.
PharmGKBPA162387168.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG129576.
HOGENOMHOG000112445.
HOVERGENHBG082564.
InParanoidA6NMN3.
OMAECCLQEL.
OrthoDBEOG7JT6X5.
PhylomeDBA6NMN3.
TreeFamTF337124.

Gene expression databases

BgeeA6NMN3.
CleanExHS_FAM170B.
GenevestigatorA6NMN3.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi170370.
NextBio88885.
PROA6NMN3.

Entry information

Entry nameF170B_HUMAN
AccessionPrimary (citable) accession number: A6NMN3
Secondary accession number(s): Q86WY6, Q8N6K8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: July 24, 2007
Last modified: April 16, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 10

Human chromosome 10: entries, gene names and cross-references to MIM