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Protein

Transmembrane protein 212

Gene

TMEM212

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Protein family/group databases

TCDBi1.A.37.7.1 the cd20 ca(2+) channel (cd20) family

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 212
Gene namesi
Name:TMEM212
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000186329.9
HGNCiHGNC:34295 TMEM212
neXtProtiNX_A6NML5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Transmembranei76 – 96HelicalSequence analysisAdd BLAST21
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei148 – 168HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000186329
PharmGKBiPA162406475

Polymorphism and mutation databases

BioMutaiTMEM212

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003412071 – 194Transmembrane protein 212Add BLAST194

Proteomic databases

PaxDbiA6NML5
PRIDEiA6NML5

Expressioni

Gene expression databases

BgeeiENSG00000186329
CleanExiHS_TMEM212
ExpressionAtlasiA6NML5 baseline and differential
GenevisibleiA6NML5 HS

Organism-specific databases

HPAiHPA045736
HPA053134

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000334072

Structurei

3D structure databases

ProteinModelPortaliA6NML5
SMRiA6NML5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IWY4 Eukaryota
ENOG410YJC5 LUCA
GeneTreeiENSGT00390000016029
HOGENOMiHOG000154625
HOVERGENiHBG095589
InParanoidiA6NML5
KOiK22196
OMAiCVDPPHY
OrthoDBiEOG091G0OD0
PhylomeDBiA6NML5
TreeFamiTF337661

Family and domain databases

InterProiView protein in InterPro
IPR030417 MS4A
PANTHERiPTHR23320 PTHR23320, 1 hit

Sequencei

Sequence statusi: Complete.

A6NML5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGLYQAAGR ILVTLGILSV CSGVIAFFPV FSYKPWFTGW SVRIACPIWN
60 70 80 90 100
GALAITTGVL LLLAYREWTQ RYLGEATFTF VILSIMGCPL HFAIALESAL
110 120 130 140 150
LGPYCFYSFS GIAGTNYLGY AVTFPYPYAK FPLACVDPPH YEEYHLTLQA
160 170 180 190
LDLCLSFTLL CTSLTVFIKL SARLIQNGHI NMQLPAGNPN PFSP
Length:194
Mass (Da):21,425
Last modified:January 15, 2008 - v2
Checksum:i940FF9F9630714AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK026825 mRNA No translation available.
AC055714 Genomic DNA No translation available.
CCDSiCCDS46958.1
RefSeqiNP_001157908.1, NM_001164436.1
XP_011511119.1, XM_011512817.1
UniGeneiHs.642307

Genome annotation databases

EnsembliENST00000334567; ENSP00000334072; ENSG00000186329
ENST00000619900; ENSP00000484106; ENSG00000186329
GeneIDi389177
KEGGihsa:389177
UCSCiuc003fhw.2 human

Similar proteinsi

Entry informationi

Entry nameiTM212_HUMAN
AccessioniPrimary (citable) accession number: A6NML5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: January 15, 2008
Last modified: February 28, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health