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Protein

Leucine-rich repeat-containing protein 30

Gene

LRRC30

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 30
Gene namesi
Name:LRRC30
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

HGNCiHGNC:30219. LRRC30.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134945901.

Polymorphism and mutation databases

BioMutaiLRRC30.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini2 – 301300Leucine-rich repeat-containing protein 30PRO_0000310986Add
BLAST

Proteomic databases

PaxDbiA6NM36.
PRIDEiA6NM36.

PTM databases

iPTMnetiA6NM36.
PhosphoSiteiA6NM36.

Expressioni

Gene expression databases

CleanExiHS_LRRC30.

Organism-specific databases

HPAiHPA041039.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000372959.

Structurei

3D structure databases

ProteinModelPortaliA6NM36.
SMRiA6NM36. Positions 38-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati72 – 9322LRR 1Add
BLAST
Repeati95 – 11622LRR 2Add
BLAST
Repeati118 – 13922LRR 3Add
BLAST
Repeati141 – 16323LRR 4Add
BLAST
Repeati164 – 18522LRR 5Add
BLAST
Repeati187 – 20822LRR 6Add
BLAST
Repeati210 – 23122LRR 7Add
BLAST
Repeati233 – 25422LRR 8Add
BLAST
Repeati265 – 28723LRR 9Add
BLAST

Sequence similaritiesi

Contains 9 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00840000129686.
HOGENOMiHOG000116557.
HOVERGENiHBG099497.
InParanoidiA6NM36.
OMAiGMTDIPD.
OrthoDBiEOG79PJPQ.
PhylomeDBiA6NM36.
TreeFamiTF333627.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 6 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 8 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NM36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGARQSRASS KDKGPKRMLF TGRRQKFSPW DDALLSGRDP RSLLKRGMHH
60 70 80 90 100
VSFSLVTRGM TDIPDFLWGL SEVQKLNLSH NQLRVLPPEV GKLTRIVVLN
110 120 130 140 150
LCGNRLKSLP REVSLLQCLK VLFVNMNCLT EVPAELSLCR KLEVLSLSHN
160 170 180 190 200
CLSQLPACFA DLSRLRKLNL SNNFFAHIPM CVFSLKELIF LHVGSNRLEN
210 220 230 240 250
IAESIQHLAS LQIFIAEGNN IHSFPRSLCL VTSLELLNLN NNDIQTLPSE
260 270 280 290 300
LHLLCRLVRI AWNPMDKGLH ISHNPLSKPL PELVEGGLEM LFGYLKDKKH

T
Length:301
Mass (Da):34,034
Last modified:July 24, 2007 - v1
Checksum:i42070AA183AB3FCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005270 Genomic DNA. No translation available.
CCDSiCCDS42409.1.
RefSeqiNP_001099051.1. NM_001105581.1.
UniGeneiHs.647588.

Genome annotation databases

EnsembliENST00000383467; ENSP00000372959; ENSG00000206422.
GeneIDi339291.
KEGGihsa:339291.
UCSCiuc010wzk.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005270 Genomic DNA. No translation available.
CCDSiCCDS42409.1.
RefSeqiNP_001099051.1. NM_001105581.1.
UniGeneiHs.647588.

3D structure databases

ProteinModelPortaliA6NM36.
SMRiA6NM36. Positions 38-277.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000372959.

PTM databases

iPTMnetiA6NM36.
PhosphoSiteiA6NM36.

Polymorphism and mutation databases

BioMutaiLRRC30.

Proteomic databases

PaxDbiA6NM36.
PRIDEiA6NM36.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000383467; ENSP00000372959; ENSG00000206422.
GeneIDi339291.
KEGGihsa:339291.
UCSCiuc010wzk.3. human.

Organism-specific databases

CTDi339291.
GeneCardsiLRRC30.
HGNCiHGNC:30219. LRRC30.
HPAiHPA041039.
neXtProtiNX_A6NM36.
PharmGKBiPA134945901.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00840000129686.
HOGENOMiHOG000116557.
HOVERGENiHBG099497.
InParanoidiA6NM36.
OMAiGMTDIPD.
OrthoDBiEOG79PJPQ.
PhylomeDBiA6NM36.
TreeFamiTF333627.

Miscellaneous databases

GenomeRNAii339291.
PROiA6NM36.

Gene expression databases

CleanExiHS_LRRC30.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 6 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 8 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiLRC30_HUMAN
AccessioniPrimary (citable) accession number: A6NM36
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: July 24, 2007
Last modified: June 8, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.