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A6NM15

- CBWD7_HUMAN

UniProt

A6NM15 - CBWD7_HUMAN

Protein

Putative COBW domain-containing protein 7

Gene

CBWD7

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 3 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi55 – 584ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative COBW domain-containing protein 7
    Alternative name(s):
    Putative cobalamin synthase W domain-containing protein 7
    Gene namesi
    Name:CBWD7
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:31977. CBWD7.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA145149368.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 247247Putative COBW domain-containing protein 7PRO_0000344630Add
    BLAST

    Proteomic databases

    PRIDEiA6NM15.

    PTM databases

    PhosphoSiteiA6NM15.

    Expressioni

    Gene expression databases

    BgeeiA6NM15.
    GenevestigatoriA6NM15.

    Organism-specific databases

    HPAiHPA042759.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000366608.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NM15.
    SMRiA6NM15. Positions 14-225.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini126 – 229104CobW C-terminalAdd
    BLAST

    Sequence similaritiesi

    Belongs to the CobW family.Curated
    Contains 1 cobW C-terminal domain.Curated

    Phylogenomic databases

    HOGENOMiHOG000182211.
    HOVERGENiHBG056297.
    InParanoidiA6NM15.

    Family and domain databases

    Gene3Di3.30.1220.10. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR011629. Cbl_biosynth_CobW-like_C.
    IPR003495. CobW/HypB/UreG_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF02492. cobW. 1 hit.
    PF07683. CobW_C. 1 hit.
    [Graphical view]
    SMARTiSM00833. CobW_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF90002. SSF90002. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6NM15-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFWVDAELGS DIYLDGIITI VDSKYGLKHL TEEKPDGLIN EATRQVALAD    50
    IILINKTDLV PEEDVKKLRT TIRSINGLGQ ILETQRSRVD LSNVLDLHAF 100
    DSLSGISLQK KLQHVPGTQP HLDQSIVTIT FEVPGNAKEE HLNMFIQNLL 150
    WEKNVRNKDN HCMEVIRLKG LVSIKDKSQQ VIVQGVHELY DLEETPVSWK 200
    DDTERTNRLV LIGRNLDKDI LKQLFIATVT ETEKQWTTHF KEDQVCT 247
    Length:247
    Mass (Da):28,232
    Last modified:July 22, 2008 - v3
    Checksum:i9961C0AF449D0F87
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC129778 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000377391; ENSP00000366608; ENSG00000215126.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC129778 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali A6NM15.
    SMRi A6NM15. Positions 14-225.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000366608.

    PTM databases

    PhosphoSitei A6NM15.

    Proteomic databases

    PRIDEi A6NM15.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000377391 ; ENSP00000366608 ; ENSG00000215126 .

    Organism-specific databases

    GeneCardsi GC09P042836.
    HGNCi HGNC:31977. CBWD7.
    HPAi HPA042759.
    neXtProti NX_A6NM15.
    PharmGKBi PA145149368.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000182211.
    HOVERGENi HBG056297.
    InParanoidi A6NM15.

    Miscellaneous databases

    NextBioi 21547831.

    Gene expression databases

    Bgeei A6NM15.
    Genevestigatori A6NM15.

    Family and domain databases

    Gene3Di 3.30.1220.10. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR011629. Cbl_biosynth_CobW-like_C.
    IPR003495. CobW/HypB/UreG_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF02492. cobW. 1 hit.
    PF07683. CobW_C. 1 hit.
    [Graphical view ]
    SMARTi SM00833. CobW_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF90002. SSF90002. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCBWD7_HUMAN
    AccessioniPrimary (citable) accession number: A6NM15
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 22, 2008
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 52 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Could be the product of a pseudogene.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3