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A6NM15

- CBWD7_HUMAN

UniProt

A6NM15 - CBWD7_HUMAN

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Protein

Putative COBW domain-containing protein 7

Gene
CBWD7
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi55 – 584ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative COBW domain-containing protein 7
Alternative name(s):
Putative cobalamin synthase W domain-containing protein 7
Gene namesi
Name:CBWD7
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:31977. CBWD7.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA145149368.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Putative COBW domain-containing protein 7PRO_0000344630Add
BLAST

Proteomic databases

PRIDEiA6NM15.

PTM databases

PhosphoSiteiA6NM15.

Expressioni

Gene expression databases

BgeeiA6NM15.
GenevestigatoriA6NM15.

Organism-specific databases

HPAiHPA042759.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000366608.

Structurei

3D structure databases

ProteinModelPortaliA6NM15.
SMRiA6NM15. Positions 14-225.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini126 – 229104CobW C-terminalAdd
BLAST

Sequence similaritiesi

Belongs to the CobW family.

Phylogenomic databases

HOGENOMiHOG000182211.
HOVERGENiHBG056297.
InParanoidiA6NM15.

Family and domain databases

Gene3Di3.30.1220.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR011629. Cbl_biosynth_CobW-like_C.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02492. cobW. 1 hit.
PF07683. CobW_C. 1 hit.
[Graphical view]
SMARTiSM00833. CobW_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90002. SSF90002. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NM15-1 [UniParc]FASTAAdd to Basket

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MFWVDAELGS DIYLDGIITI VDSKYGLKHL TEEKPDGLIN EATRQVALAD    50
IILINKTDLV PEEDVKKLRT TIRSINGLGQ ILETQRSRVD LSNVLDLHAF 100
DSLSGISLQK KLQHVPGTQP HLDQSIVTIT FEVPGNAKEE HLNMFIQNLL 150
WEKNVRNKDN HCMEVIRLKG LVSIKDKSQQ VIVQGVHELY DLEETPVSWK 200
DDTERTNRLV LIGRNLDKDI LKQLFIATVT ETEKQWTTHF KEDQVCT 247
Length:247
Mass (Da):28,232
Last modified:July 22, 2008 - v3
Checksum:i9961C0AF449D0F87
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC129778 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000377391; ENSP00000366608; ENSG00000215126.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC129778 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A6NM15.
SMRi A6NM15. Positions 14-225.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000366608.

PTM databases

PhosphoSitei A6NM15.

Proteomic databases

PRIDEi A6NM15.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000377391 ; ENSP00000366608 ; ENSG00000215126 .

Organism-specific databases

GeneCardsi GC09P042836.
HGNCi HGNC:31977. CBWD7.
HPAi HPA042759.
neXtProti NX_A6NM15.
PharmGKBi PA145149368.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000182211.
HOVERGENi HBG056297.
InParanoidi A6NM15.

Miscellaneous databases

NextBioi 21547831.

Gene expression databases

Bgeei A6NM15.
Genevestigatori A6NM15.

Family and domain databases

Gene3Di 3.30.1220.10. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR011629. Cbl_biosynth_CobW-like_C.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF02492. cobW. 1 hit.
PF07683. CobW_C. 1 hit.
[Graphical view ]
SMARTi SM00833. CobW_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF90002. SSF90002. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCBWD7_HUMAN
AccessioniPrimary (citable) accession number: A6NM15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 22, 2008
Last modified: April 16, 2014
This is version 51 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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