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Protein

Transmembrane protein 210

Gene

TMEM210

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-33252-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 210
Gene namesi
Name:TMEM210
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:34059. TMEM210.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini32 – 47ExtracellularSequence analysisAdd BLAST16
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 147CytoplasmicSequence analysisAdd BLAST79

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185863.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000032908032 – 147Transmembrane protein 210Add BLAST116

Proteomic databases

PaxDbiA6NLX4.
PRIDEiA6NLX4.

PTM databases

PhosphoSitePlusiA6NLX4.

Expressioni

Gene expression databases

BgeeiENSG00000185863.
CleanExiHS_TMEM210.
ExpressionAtlasiA6NLX4. baseline and differential.

Organism-specific databases

HPAiHPA066907.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000456333.

Structurei

3D structure databases

ProteinModelPortaliA6NLX4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi138 – 146Poly-Pro9

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JCD8. Eukaryota.
ENOG4111BBA. LUCA.
GeneTreeiENSGT00390000008939.
HOVERGENiHBG094898.
InParanoidiA6NLX4.
OMAiVHVESHL.
OrthoDBiEOG091G0Y46.
PhylomeDBiA6NLX4.
TreeFamiTF338189.

Family and domain databases

InterProiIPR028123. TMEM210.
[Graphical view]
PfamiPF15195. TMEM210. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6NLX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPGPWPVSC LRGGPLGLTY LSLLLIPAAA GTYCECSLGL SREALIALLV
60 70 80 90 100
VLAGISASCF CALVIVAIGV LRAKGETCPR QVDNRLVENF GVQEDLMDLH
110 120 130 140
PVYVESQLMD ADLEVSLVPP LEDQSLVAIP MEASSEEPPP PPPLPPE
Length:147
Mass (Da):15,516
Last modified:July 24, 2007 - v1
Checksum:i636450CC13451BF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929554 Genomic DNA. No translation available.
CCDSiCCDS65197.1.
RefSeqiNP_001269406.1. NM_001282477.1.
UniGeneiHs.512463.

Genome annotation databases

EnsembliENST00000413619; ENSP00000456333; ENSG00000185863.
GeneIDi100505993.
KEGGihsa:100505993.
UCSCiuc033dlm.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929554 Genomic DNA. No translation available.
CCDSiCCDS65197.1.
RefSeqiNP_001269406.1. NM_001282477.1.
UniGeneiHs.512463.

3D structure databases

ProteinModelPortaliA6NLX4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000456333.

PTM databases

PhosphoSitePlusiA6NLX4.

Proteomic databases

PaxDbiA6NLX4.
PRIDEiA6NLX4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413619; ENSP00000456333; ENSG00000185863.
GeneIDi100505993.
KEGGihsa:100505993.
UCSCiuc033dlm.2. human.

Organism-specific databases

CTDi100505993.
GeneCardsiTMEM210.
HGNCiHGNC:34059. TMEM210.
HPAiHPA066907.
neXtProtiNX_A6NLX4.
OpenTargetsiENSG00000185863.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JCD8. Eukaryota.
ENOG4111BBA. LUCA.
GeneTreeiENSGT00390000008939.
HOVERGENiHBG094898.
InParanoidiA6NLX4.
OMAiVHVESHL.
OrthoDBiEOG091G0Y46.
PhylomeDBiA6NLX4.
TreeFamiTF338189.

Enzyme and pathway databases

BioCyciZFISH:G66-33252-MONOMER.

Miscellaneous databases

PROiA6NLX4.

Gene expression databases

BgeeiENSG00000185863.
CleanExiHS_TMEM210.
ExpressionAtlasiA6NLX4. baseline and differential.

Family and domain databases

InterProiIPR028123. TMEM210.
[Graphical view]
PfamiPF15195. TMEM210. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTM210_HUMAN
AccessioniPrimary (citable) accession number: A6NLX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 24, 2007
Last modified: November 2, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.