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Protein
Submitted name:

Polypyrimidine tract binding protein 1, isoform CRA_b

Gene

PTBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Polypyrimidine tract binding protein 1, isoform CRA_bImported
Submitted name:
Polypyrimidine tract-binding protein 1Imported
Gene namesi
Name:PTBP1Imported
ORF Names:hCG_20560Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:9583. PTBP1.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000011304.
PharmGKBiPA33934.

Expressioni

Gene expression databases

BgeeiENSG00000011304.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000349428.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 113RRM (RNA recognition motif)InterPro annotationAdd BLAST85
Domaini154 – 230RRM (RNA recognition motif)InterPro annotationAdd BLAST77
Domaini333 – 407RRM (RNA recognition motif)InterPro annotationAdd BLAST75
Domaini450 – 525RRM (RNA recognition motif)InterPro annotationAdd BLAST76

Phylogenomic databases

eggNOGiKOG1190. Eukaryota.
ENOG410XPMZ. LUCA.
GeneTreeiENSGT00550000074508.
HOGENOMiHOG000045782.
HOVERGENiHBG055095.

Family and domain databases

InterProiView protein in InterPro
IPR006536. HnRNP-L/PTB.
IPR000504. RRM_dom.
PfamiView protein in Pfam
PF00076. RRM_1. 2 hits.
SMARTiView protein in SMART
SM00360. RRM. 4 hits.
SUPFAMiSSF54928. SSF54928. 4 hits.
TIGRFAMsiTIGR01649. hnRNP-L_PTB. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 4 hits.

Sequencei

Sequence statusi: Complete.

A6NLN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSNSASAAN GNDSKKFKGD SRSAGVPSRV IHIRKLPIDV TEGEVISLGL
60 70 80 90 100
PFGKVTNLLM LKGKNQAFIE MNTEEAANTM VNYYTSVTPV LRGQPIYIQF
110 120 130 140 150
SNHKELKTDS SPNQARAQAA LQAVNSVQSG NLALAASAAA VDAGMAMAGQ
160 170 180 190 200
SPVLRIIVEN LFYPVTLDVL HQIFSKFGTV LKIITFTKNN QFQALLQYAD
210 220 230 240 250
PVSAQHAKLS LDGQNIYNAC CTLRIDFSKL TSLNVKYNND KSRDYTRPDL
260 270 280 290 300
PSGDSQPSLD QTMAAAFGAP GIISASPYAG AGFPPTFAIP QAAGLSVPNV
310 320 330 340 350
HGALAPLAIP SAAAAAAAAG RIAIPGLAGA GNSVLLVSNL NPERVTPQSL
360 370 380 390 400
FILFGVYGDV QRVKILFNKK ENALVQMADG NQAQLAMSHL NGHKLHGKPI
410 420 430 440 450
RITLSKHQNV QLPREGQEDQ GLTKDYGNSP LHRFKKPGSK NFQNIFPPSA
460 470 480 490 500
TLHLSNIPPS VSEEDLKVLF SSNGGVVKGF KFFQKDRKMA LIQMGSVEEA
510 520
VQALIDLHNH DLGENHHLRV SFSKSTI
Length:527
Mass (Da):56,511
Last modified:October 29, 2014 - v4
Checksum:i3F4186135568E295
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006273 Genomic DNA. No translation available.
CH471242 Genomic DNA. Translation: EAW61153.1.
UniGeneiHs.172550.

Genome annotation databases

EnsembliENST00000350092; ENSP00000342332; ENSG00000011304.
UCSCiuc060qrb.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006273 Genomic DNA. No translation available.
CH471242 Genomic DNA. Translation: EAW61153.1.
UniGeneiHs.172550.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000349428.

Protocols and materials databases

DNASUi5725.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000350092; ENSP00000342332; ENSG00000011304.
UCSCiuc060qrb.1. human.

Organism-specific databases

HGNCiHGNC:9583. PTBP1.
OpenTargetsiENSG00000011304.
PharmGKBiPA33934.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1190. Eukaryota.
ENOG410XPMZ. LUCA.
GeneTreeiENSGT00550000074508.
HOGENOMiHOG000045782.
HOVERGENiHBG055095.

Miscellaneous databases

ChiTaRSiPTBP1. human.

Gene expression databases

BgeeiENSG00000011304.

Family and domain databases

InterProiView protein in InterPro
IPR006536. HnRNP-L/PTB.
IPR000504. RRM_dom.
PfamiView protein in Pfam
PF00076. RRM_1. 2 hits.
SMARTiView protein in SMART
SM00360. RRM. 4 hits.
SUPFAMiSSF54928. SSF54928. 4 hits.
TIGRFAMsiTIGR01649. hnRNP-L_PTB. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 4 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA6NLN1_HUMAN
AccessioniPrimary (citable) accession number: A6NLN1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: October 29, 2014
Last modified: May 10, 2017
This is version 88 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.