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Protein

Tripartite motif-containing protein 64C

Gene

TRIM64C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri15 – 56RING-typePROSITE-ProRule annotationAdd BLAST42
Zinc fingeri87 – 128B box-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Tripartite motif-containing protein 64C
Gene namesi
Name:TRIM64C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

EuPathDBiHostDB:ENSG00000214891.8
HGNCiHGNC:37148 TRIM64C
neXtProtiNX_A6NLI5

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003402481 – 450Tripartite motif-containing protein 64CAdd BLAST450

Proteomic databases

PaxDbiA6NLI5
PRIDEiA6NLI5

Expressioni

Organism-specific databases

HPAiHPA045370

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000431987

Structurei

3D structure databases

ProteinModelPortaliA6NLI5
SMRiA6NLI5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini269 – 450B30.2/SPRYPROSITE-ProRule annotationAdd BLAST182

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili191 – 218Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the TRIM/RBCC family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri15 – 56RING-typePROSITE-ProRule annotationAdd BLAST42
Zinc fingeri87 – 128B box-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
GeneTreeiENSGT00840000129725
HOGENOMiHOG000234135
HOVERGENiHBG108727
InParanoidiA6NLI5
KOiK12019
OMAiNEICHQL
OrthoDBiEOG091G06US
PhylomeDBiA6NLI5

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di3.30.40.101 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR003877 SPRY_dom
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF00622 SPRY, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

A6NLI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSDTLRVFQ NELICCICVN YFIDPVTTDC VHSFCRPCLC LCSEEGRAPM
60 70 80 90 100
RCPLCRKISE KPNFNTNVAL KKLASLARQT RPQNINSSDN ICVLHEETKE
110 120 130 140 150
LFCEADKRLL CGPCSESPEH MAHSHSPIGW AAEECRVQKL IKEMDYLWKI
160 170 180 190 200
NQETQNNLNQ ETSKFCSLVD YVSLRKVIIT IQYQKMHIFL DEEEQRHLQA
210 220 230 240 250
LEREAKELFQ QLQDSQVRMT QHLEGMKDMY RELWETYHMP DVELLQDVGN
260 270 280 290 300
ISARTDLAQM PKPQPVNPEL TSWCITGVLD MLNNFRVDNA LSTEMTPCYI
310 320 330 340 350
SLSEDVRRVI FGDDHRSAPM DPQGVESFAV WCAQAFTSGK HYWEVDVTHS
360 370 380 390 400
SNWILGVCRD SRTADTNIVI DSDKTFFSIS SKTSNHYSLS TNSPPLIQYV
410 420 430 440 450
QRPLGWVGVF LDYDNGSVSF FDVSKGSLIY GFPPSSFSSP LRPFFCFGCT
Length:450
Mass (Da):51,540
Last modified:March 28, 2018 - v4
Checksum:i8541F4CEAC0D1744
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084851 Genomic DNA No translation available.
RefSeqiNP_001193560.1, NM_001206631.1
UniGeneiHs.740240

Genome annotation databases

EnsembliENST00000617704; ENSP00000481815; ENSG00000214891
GeneIDi646754
KEGGihsa:646754

Similar proteinsi

Entry informationi

Entry nameiTR64C_HUMAN
AccessioniPrimary (citable) accession number: A6NLI5
Secondary accession number(s): A0A087WYH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 28, 2018
Last modified: April 25, 2018
This is version 84 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome