A6NLI5 (TR64C_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative tripartite motif-containing protein 64C

Gene names

Name:

TRIM64C

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Sequence similarities	Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 B30.2/SPRY domain. Contains 1 RING-type zinc finger.
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Domain	Coiled coil Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Putative tripartite motif-containing protein 64C		PRO_0000340248
Regions
	Domain	266 – 447	182	B30.2/SPRY
	Zinc finger	15 – 56	42	RING-type
	Zinc finger	87 – 128	42	B box-type
	Coiled coil	186 – 218	33	Potential

Sequences

	Sequence		Length	Mass (Da)
	A6NLI5 [UniParc]. Last modified July 1, 2008. Version 3. Checksum: 36F65FB726EDA4D3	FASTA	447	51,329
	10 20 30 40 50 60 MDSDTLRVFQ NELICCICVN YFIDPVTTDC VHSFCRPCLC LCSEEGRAPM RCPLCRKISE 70 80 90 100 110 120 KPNFNTNVAL KKLASLARQT RPQNINSSDN ICVLHEETKE LFCEADKRLL CGPCSESPEH 130 140 150 160 170 180 MAHSHSPIGW AAEECREKLI KEMDYLWKIN QETQNNLNQE TSKFCSLVED KRNRIVYRYQ 190 200 210 220 230 240 KMHIFLDEEE QRHLQALERE AKELFQQLQD SQVRMTQHLE GMKDMYRELW ETYHMPDVEL 250 260 270 280 290 300 LQDVGNISAS RTDLAQMPKP QPVNPELTSW CITGVLDMLN NFRVDNALST EMTPCYISLS 310 320 330 340 350 360 EDVRRVIFGD DHRSAPMDPQ GVESFAVWCA QAFTSGKHYW EVDVTHSSNW ILGVCRDSRT 370 380 390 400 410 420 ADTNIVIDSD KTFFSISSKT SNHYSLSTNS PPLIQYVQRP LGWVGVFLDY DNGSVSFFDV 430 440 SKGSLIYGFP PSSFSSPLRP FFCFGCT

References

[1]

"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC084851 Genomic DNA. No translation available.
IPI	IPI00888634.
UniGene	Hs.740240.
3D structure databases
ProteinModelPortal	A6NLI5.
ModBase	Search...
Proteomic databases
PaxDb	A6NLI5.
PRIDE	A6NLI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
GeneCards	GC11M049075.
HGNC	HGNC:37148. TRIM64C.
HPA	HPA045370.
neXtProt	NX_A6NLI5.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG260754.
HOGENOM	HOG000234135.
HOVERGEN	HBG108727.
InParanoid	A6NLI5.
OrthoDB	EOG4ZPDV5.
Gene expression databases
Genevestigator	A6NLI5.
Family and domain databases
Gene3D	3.30.40.10. 1 hit.
InterPro	IPR001870. B30.2/SPRY. IPR003879. Butyrophylin. IPR008985. ConA-like_lec_gl_sf. IPR003877. SPRY_rcpt. IPR000315. Znf_B-box. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. [Graphical view]
Pfam	PF00622. SPRY. 1 hit. PF00643. zf-B_box. 1 hit. [Graphical view]
PRINTS	PR01407. BUTYPHLNCDUF.
SMART	SM00336. BBOX. 1 hit. SM00184. RING. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS50188. B302_SPRY. 1 hit. PS50119. ZF_BBOX. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TR64C_HUMAN

Accession

Primary (citable) accession number: A6NLI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 51 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.