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Protein

UPF0524 protein C3orf70

Gene

C3orf70

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0524 protein C3orf70
Gene namesi
Name:C3orf70
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:33731. C3orf70.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162379707.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 250250UPF0524 protein C3orf70PRO_0000319976Add
BLAST

Proteomic databases

MaxQBiA6NLC5.
PaxDbiA6NLC5.
PRIDEiA6NLC5.

PTM databases

PhosphoSiteiA6NLC5.

Expressioni

Gene expression databases

BgeeiA6NLC5.
CleanExiHS_C3orf70.
GenevestigatoriA6NLC5.

Organism-specific databases

HPAiHPA041861.

Structurei

3D structure databases

ProteinModelPortaliA6NLC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0524 family.Curated

Phylogenomic databases

eggNOGiNOG40600.
GeneTreeiENSGT00390000006618.
HOGENOMiHOG000043069.
HOVERGENiHBG095343.
InParanoidiA6NLC5.
OMAiPAPHSHK.
OrthoDBiEOG7QC7XH.
PhylomeDBiA6NLC5.
TreeFamiTF328625.

Family and domain databases

InterProiIPR029670. UPF0524_fam.
[Graphical view]
PANTHERiPTHR31785:SF2. PTHR31785:SF2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NLC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAAASPASE RGWKSEKLDE AQALARSCAA RRPDFQPCDG LSICATHSHG
60 70 80 90 100
KCFKLHWCCH LGWCHCKYMY QPMTPVEQLP STEIPARPRE PTNTIQISVS
110 120 130 140 150
LTEHFLKFAS VFQPPLPPDS PRYCMISDLF IDNYQVKCIN GKMCYVQKQP
160 170 180 190 200
APHSHRMSPE EVSAHDALIS KESNTPKIDH CSSPSSSEDS GINAIGAHYV
210 220 230 240 250
ESCDEDTEEG AELSSEEDYS PESSWEPDEC TLLSPSQSDL EVIETIETTV
Length:250
Mass (Da):27,769
Last modified:July 24, 2007 - v1
Checksum:i5B2930FDE8905AC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025573 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW78232.1.
BC137178 mRNA. Translation: AAI37179.1.
BC137179 mRNA. Translation: AAI37180.1.
BC150565 mRNA. Translation: AAI50566.1.
CCDSiCCDS33900.1.
RefSeqiNP_001020437.1. NM_001025266.1.
UniGeneiHs.380048.

Genome annotation databases

EnsembliENST00000335012; ENSP00000334974; ENSG00000187068.
GeneIDi285382.
KEGGihsa:285382.
UCSCiuc003fpd.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025573 Genomic DNA. No translation available.
CH471052 Genomic DNA. Translation: EAW78232.1.
BC137178 mRNA. Translation: AAI37179.1.
BC137179 mRNA. Translation: AAI37180.1.
BC150565 mRNA. Translation: AAI50566.1.
CCDSiCCDS33900.1.
RefSeqiNP_001020437.1. NM_001025266.1.
UniGeneiHs.380048.

3D structure databases

ProteinModelPortaliA6NLC5.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiA6NLC5.

Proteomic databases

MaxQBiA6NLC5.
PaxDbiA6NLC5.
PRIDEiA6NLC5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000335012; ENSP00000334974; ENSG00000187068.
GeneIDi285382.
KEGGihsa:285382.
UCSCiuc003fpd.3. human.

Organism-specific databases

CTDi285382.
GeneCardsiGC03M184795.
HGNCiHGNC:33731. C3orf70.
HPAiHPA041861.
neXtProtiNX_A6NLC5.
PharmGKBiPA162379707.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG40600.
GeneTreeiENSGT00390000006618.
HOGENOMiHOG000043069.
HOVERGENiHBG095343.
InParanoidiA6NLC5.
OMAiPAPHSHK.
OrthoDBiEOG7QC7XH.
PhylomeDBiA6NLC5.
TreeFamiTF328625.

Miscellaneous databases

ChiTaRSiC3orf70. human.
GenomeRNAii285382.
NextBioi95491.

Gene expression databases

BgeeiA6NLC5.
CleanExiHS_C3orf70.
GenevestigatoriA6NLC5.

Family and domain databases

InterProiIPR029670. UPF0524_fam.
[Graphical view]
PANTHERiPTHR31785:SF2. PTHR31785:SF2. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiCC070_HUMAN
AccessioniPrimary (citable) accession number: A6NLC5
Secondary accession number(s): B2RNY2, B9EH83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 24, 2007
Last modified: January 7, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.