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Protein
Submitted name:

Actin, alpha skeletal muscle

Gene

ACTA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiA6NL76.

Names & Taxonomyi

Protein namesi
Submitted name:
Actin, alpha skeletal muscleImported
Gene namesi
Name:ACTA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:129. ACTA1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143632.

PTM / Processingi

Proteomic databases

PaxDbiA6NL76.
PeptideAtlasiA6NL76.
PRIDEiA6NL76.

Expressioni

Gene expression databases

BgeeiENSG00000143632.
ExpressionAtlasiA6NL76. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000355645.

Structurei

3D structure databases

ProteinModelPortaliA6NL76.
SMRiA6NL76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
GeneTreeiENSGT00760000118957.
HOGENOMiHOG000233340.
HOVERGENiHBG003771.

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 2 hits.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NL76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCDEDETTAL VCDNGSGLVK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG
60 70 80 90 100
QKDSYVGDEA QSKRGILTLK YPIEHGIITN WDDMEKIWHH TFYNELRVAP
110 120 130 140 150
EEHPTLLTEA PLNPKANREK MTQIMFETFN VPAMYVAIQA VLSLYASGRT
160 170 180 190 200
TGIVLDSGDG IMKCDIDIRK DLYANNVMSG GTTMYPGIAD RMQKEITALA
210 220 230 240 250
PSTMKIKIIA PPERKYSVWI GGSILASLST FQQMWITKQE YDEAGPSIVH

RKCF
Length:254
Mass (Da):28,165
Last modified:October 29, 2014 - v3
Checksum:iDAB47E6633211520
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL160004 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000366683; ENSP00000355644; ENSG00000143632.
UCSCiuc057qfz.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL160004 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliA6NL76.
SMRiA6NL76.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000355645.

Proteomic databases

PaxDbiA6NL76.
PeptideAtlasiA6NL76.
PRIDEiA6NL76.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000366683; ENSP00000355644; ENSG00000143632.
UCSCiuc057qfz.1. human.

Organism-specific databases

HGNCiHGNC:129. ACTA1.
OpenTargetsiENSG00000143632.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
GeneTreeiENSGT00760000118957.
HOGENOMiHOG000233340.
HOVERGENiHBG003771.

Enzyme and pathway databases

SignaLinkiA6NL76.

Miscellaneous databases

ChiTaRSiACTA1. human.

Gene expression databases

BgeeiENSG00000143632.
ExpressionAtlasiA6NL76. baseline and differential.

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 2 hits.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA6NL76_HUMAN
AccessioniPrimary (citable) accession number: A6NL76
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: October 29, 2014
Last modified: November 2, 2016
This is version 71 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.