Reviewed, UniProtKB/Swiss-Prot A6NKW6 (F159B_HUMAN)

Names and origin

Protein names

Recommended name:
    UPF0514 membrane protein FAM159B

Gene names

Name:

FAM159B

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the UPF0514 family.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Polymorphism
Domain	Transmembrane
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	UPF0514 membrane protein FAM159B		PRO_0000317723
Regions
	Transmembrane	65 – 85	21	Potential
Natural variations
	Natural variant	5	1	S → R: dbSNP rs16893053.		VAR_053995
	Natural variant	111	1	A → P: dbSNP rs2305962.		VAR_053996

Sequences

	Sequence		Length	Mass (Da)
	A6NKW6-1 [UniParc]. Last modified January 15, 2008. Version 2. Checksum: 44B58414266BF516	FASTA	160	17,663
	10 20 30 40 50 60 MSEASRLCSG YYSLNQSFVE PFQCPRRGEG AALQYCCGFA DLKYCCSEPG SYFPYKHSYM 70 80 90 100 110 120 WSLSIGALIG LGIAALVLLA FVISVCVLCY LFLYTKPQRL DTGLKLQHLE ASSTQEGKSN 130 140 150 160 GKTKALNSNA ASNATNETYY EADDIIQEKT MDATQIHIAY

References

[1]

"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M. Nature 431:268-274(2004) [PubMed: 15372022] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC008898 Genomic DNA. No translation available.
IPI	IPI00737348.
RefSeq	XP_001720210.1.
UniGene	Hs.591776
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000145642. Homo sapiens. [Contig view]
GeneID	100132916.
Organism-specific databases
GeneCards	GC05P064023.
HGNC	HGNC:34236. FAM159B.
HPA	HPA011778.
GenAtlas	Search...
Phylogenomic databases
OMA	A6NKW6. SYMWSLS.
Gene expression databases
CleanEx	HS_FAM159B.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

F159B_HUMAN

Accession

Primary (citable) accession number: A6NKW6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 15, 2008
Last modified:	June 16, 2009
This is version 13 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)