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Protein

Purkinje cell protein 4-like protein 1

Gene

PCP4L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Purkinje cell protein 4-like protein 1
Short name:
PCP4-like protein 1
Gene namesi
Name:PCP4L1
Synonyms:IQM1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:20448. PCP4L1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA143485573.

Polymorphism and mutation databases

BioMutaiPCP4L1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6868Purkinje cell protein 4-like protein 1PRO_0000331432Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei8 – 81PhosphothreonineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiA6NKN8.
PRIDEiA6NKN8.

PTM databases

PhosphoSiteiA6NKN8.

Expressioni

Gene expression databases

BgeeiENSG00000248485.
CleanExiHS_PCP4L1.
GenevisibleiA6NKN8. HS.

Interactioni

Protein-protein interaction databases

BioGridi576410. 1 interaction.
IntActiA6NKN8. 1 interaction.
STRINGi9606.ENSP00000426296.

Structurei

3D structure databases

ProteinModelPortaliA6NKN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 6824IQAdd
BLAST

Sequence similaritiesi

Belongs to the PCP4 family.Curated
Contains 1 IQ domain.Curated

Phylogenomic databases

eggNOGiENOG410J4T9. Eukaryota.
ENOG410Z3GR. LUCA.
GeneTreeiENSGT00530000064299.
HOGENOMiHOG000054222.
HOVERGENiHBG108235.
InParanoidiA6NKN8.
OMAiANQAPGP.
PhylomeDBiA6NKN8.
TreeFamiTF336068.

Family and domain databases

InterProiIPR033234. PCP4-like_1.
[Graphical view]
PANTHERiPTHR15359:SF5. PTHR15359:SF5. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NKN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSELNTKTSP ATNQAAGQEE KGKAGNVKKA EEEEEIDIDL TAPETEKAAL
60
AIQGKFRRFQ KRKKDPSS
Length:68
Mass (Da):7,476
Last modified:April 29, 2008 - v3
Checksum:iFBCC36204571B6EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592295 Genomic DNA. No translation available.
BC028905 mRNA. No translation available.
BC147003 mRNA. Translation: AAI47004.1.
BC147004 mRNA. Translation: AAI47005.1.
CCDSiCCDS53412.1.
RefSeqiNP_001096036.1. NM_001102566.1.
UniGeneiHs.433150.

Genome annotation databases

EnsembliENST00000504449; ENSP00000426296; ENSG00000248485.
GeneIDi654790.
KEGGihsa:654790.
UCSCiuc001gad.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592295 Genomic DNA. No translation available.
BC028905 mRNA. No translation available.
BC147003 mRNA. Translation: AAI47004.1.
BC147004 mRNA. Translation: AAI47005.1.
CCDSiCCDS53412.1.
RefSeqiNP_001096036.1. NM_001102566.1.
UniGeneiHs.433150.

3D structure databases

ProteinModelPortaliA6NKN8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi576410. 1 interaction.
IntActiA6NKN8. 1 interaction.
STRINGi9606.ENSP00000426296.

PTM databases

PhosphoSiteiA6NKN8.

Polymorphism and mutation databases

BioMutaiPCP4L1.

Proteomic databases

PaxDbiA6NKN8.
PRIDEiA6NKN8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000504449; ENSP00000426296; ENSG00000248485.
GeneIDi654790.
KEGGihsa:654790.
UCSCiuc001gad.3. human.

Organism-specific databases

CTDi654790.
GeneCardsiPCP4L1.
HGNCiHGNC:20448. PCP4L1.
neXtProtiNX_A6NKN8.
PharmGKBiPA143485573.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J4T9. Eukaryota.
ENOG410Z3GR. LUCA.
GeneTreeiENSGT00530000064299.
HOGENOMiHOG000054222.
HOVERGENiHBG108235.
InParanoidiA6NKN8.
OMAiANQAPGP.
PhylomeDBiA6NKN8.
TreeFamiTF336068.

Miscellaneous databases

GenomeRNAii654790.
PROiA6NKN8.

Gene expression databases

BgeeiENSG00000248485.
CleanExiHS_PCP4L1.
GenevisibleiA6NKN8. HS.

Family and domain databases

InterProiIPR033234. PCP4-like_1.
[Graphical view]
PANTHERiPTHR15359:SF5. PTHR15359:SF5. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPC4L1_HUMAN
AccessioniPrimary (citable) accession number: A6NKN8
Secondary accession number(s): B2RV24, B9EJG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: September 7, 2016
This is version 62 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.