Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot A6NKF2 (ARI3C_HUMAN)

Last modified November 24, 2009. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    AT-rich interactive domain-containing protein 3C
Alternative name(s):
    ARID domain-containing protein 3C
Gene names
Name: ARID3C
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Subcellular location

Nucleus By similarity.

Sequence similarities

Contains 1 ARID domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   Coding sequence diversityPolymorphism
   LigandDNA-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processregulation of transcription

Inferred from electronic annotation. Source: UniProtKB-KW

transcription

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 412412AT-rich interactive domain-containing protein 3C
PRO_0000333001

Regions

Domain113 – 20593ARID
Compositional bias51 – 7525Glu-rich
Compositional bias240 – 412173Pro-rich

Natural variations

Natural variant3101R → Q: dbSNP rs12337871.
VAR_043033
Natural variant3351C → G: dbSNP rs3808869.
VAR_043034

Sequences

Sequence LengthMass (Da)Tools
A6NKF2-1 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: A4F27053248A49A7

FASTA41244,073
        10         20         30         40         50         60 
MEALQKQQAA RLAQGVGPLA PACPLLPPQP PLPDHRTLQA PEGALGNVGA EEEEDAEEDE 

        70         80         90        100        110        120 
EKREEAGAEE EAAEESRPGA QGPSSPSSQP PGLHPHEWTY EEQFKQLYEL DADPKRKEFL 

       130        140        150        160        170        180 
DDLFSFMQKR GTPVNRVPIM AKQVLDLYAL FRLVTAKGGL VEVINRKVWR EVTRGLSLPT 

       190        200        210        220        230        240 
TITSAAFTLR TQYMKYLYPY ECETRALSSP GELQAAIDSN RREGRRQAYT ATPLFGLAGP 

       250        260        270        280        290        300 
PPRGAQDPAL GPGPAPPATQ SSPGPAQGST SGLPAHACAQ LSPSPIKKEE SGIPNPCLAL 

       310        320        330        340        350        360 
PVGLALGPTR EKLAPEEPPE KRAVLMGPMD PPRPCMPPSF LPRGKVPLRE ERLDGPLNLA 

       370        380        390        400        410 
GSGISSINMA LEINGVVYTG VLFARRQPVP ASQGPTNPAP PPSTGPPSSI LP 

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed: 15164053] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"REKLES is an ARID3-restricted multifunctional domain."
Kim D., Probst L., Das C., Tucker P.W.
J. Biol. Chem. 282:15768-15777(2007) [PubMed: 17400556] [Abstract]
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

AL450283 Genomic DNA. No translation available.
IPIIPI00062225.
RefSeqNP_001017363.1.
UniGeneHs.534549

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA6NKF2.

Proteomic databases

PRIDEA6NKF2.

Genome annotation databases

EnsemblENST00000378909; ENSP00000368189; ENSG00000205143; Homo sapiens. [Genome view]
GeneID138715.
KEGGhsa:138715.
UCSCuc003zuy.1. human.

Organism-specific databases

CTD138715.
GeneCardsGC09M034613.
HGNCHGNC:21209. ARID3C.
GenAtlasSearch...

Phylogenomic databases

OMAGMPPSFL
OrthoDBEOG9284M9

Gene expression databases

CleanExHS_ARID3C.
GenevestigatorA6NKF2.

Family and domain databases

InterProIPR001606. ARID.
[Graphical view]
PfamPF01388. ARID. 1 hit.
[Graphical view]
SMARTSM00501. BRIGHT. 1 hit.
[Graphical view]
PROSITEPS51011. ARID. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio83815.

Entry information

Entry nameARI3C_HUMAN
AccessionPrimary (citable) accession number: A6NKF2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: November 24, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents