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Protein

Putative tripartite motif-containing protein 75

Gene

TRIM75P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri16 – 57RING-typePROSITE-ProRule annotationAdd BLAST42
Zinc fingeri92 – 133B box-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tripartite motif-containing protein 75
Alternative name(s):
Tripartite motif-containing protein 75 pseudogene
Gene namesi
Name:TRIM75P
Synonyms:TRIM75
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:32686. TRIM75P.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000250374.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003311921 – 468Putative tripartite motif-containing protein 75Add BLAST468

Proteomic databases

PRIDEiA6NK02.

Expressioni

Gene expression databases

CleanExiHS_TRIM75.

Structurei

3D structure databases

ProteinModelPortaliA6NK02.
SMRiA6NK02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini276 – 468B30.2/SPRYPROSITE-ProRule annotationAdd BLAST193

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili170 – 222Sequence analysisAdd BLAST53

Sequence similaritiesi

Belongs to the TRIM/RBCC family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri16 – 57RING-typePROSITE-ProRule annotationAdd BLAST42
Zinc fingeri92 – 133B box-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00760000118893.
HOVERGENiHBG001357.
InParanoidiA6NK02.
PhylomeDBiA6NK02.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR001870. B30.2/SPRY.
IPR003879. Butyrophylin_SPRY.
IPR013320. ConA-like_dom.
IPR006574. PRY.
IPR003877. SPRY_dom.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
PfamiView protein in Pfam
PF13765. PRY. 1 hit.
PF00622. SPRY. 1 hit.
PF00643. zf-B_box. 1 hit.
PRINTSiPR01407. BUTYPHLNCDUF.
SMARTiView protein in SMART
SM00336. BBOX. 1 hit.
SM00589. PRY. 1 hit.
SM00184. RING. 1 hit.
SM00449. SPRY. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiView protein in PROSITE
PS50188. B302_SPRY. 1 hit.
PS50119. ZF_BBOX. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NK02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAAALTGL QAEAKCSICL DYLSDPVTIE CGHNFCRSCI QQSWLDLQEL
60 70 80 90 100
FPCPVCRHQC QEGHFRSNTQ LGRMIEIAKL LQSTKSNKRK QEETTLCEKH
110 120 130 140 150
NQPLSVFCKE DLMVLCPLCT QPPDHQGHHV RPIEKAAIHY RKRFCSYIQP
160 170 180 190 200
LKKQLADLQK LISTQSKKPL ELREMVENQR QELSSEFEHL NQFLDREQQA
210 220 230 240 250
VLSRLAEEEK DNQQKLSANI TAFSNYSATL KSQLSKVVEL SELSELELLS
260 270 280 290 300
QIKIFYESEN ESSPSIFSIH LKRDGCSFPP QYSALQRIIK KFKVEIILDP
310 320 330 340 350
ETAHPNLIVS EDKKRVRFTK RKQKVPGFPK RFTVKPVVLG FPYFHSGRHF
360 370 380 390 400
WEIEVGDKSE WAIGICKDSL PTKARRPSSA QQECWRIELQ DDGYHAPGAF
410 420 430 440 450
PTPLLLEVKA RAIGIFLDYE MGEISFYNMA EKSHICTFTD TFTGPLRPYF
460
YVGPDSQPLR ICTGTVCE
Length:468
Mass (Da):53,678
Last modified:April 29, 2008 - v2
Checksum:i793C2F1E8EEB2BF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108465 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000503032; ENSP00000491320; ENSG00000250374.

Similar proteinsi

Entry informationi

Entry nameiTRI75_HUMAN
AccessioniPrimary (citable) accession number: A6NK02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: August 30, 2017
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families