Reviewed, UniProtKB/Swiss-Prot A6NJY1 (NHCL1_HUMAN)

Names and origin

Protein names	Recommended name:     Putative protein NHEDC1-like 1
Organism	Homo sapiens (Human) [Complete proteome]
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Uncertain.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification]
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 215	215	Putative protein NHEDC1-like 1		PRO_0000341232
Regions
	Transmembrane	27 – 47	21	Potential
	Transmembrane	51 – 71	21	Potential
	Transmembrane	87 – 107	21	Potential
	Transmembrane	135 – 155	21	Potential
	Transmembrane	174 – 194	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	A6NJY1-1 [UniParc]. Last modified July 22, 2008. Version 3. Checksum: E566A3C5F3D481B6	FASTA	215	23,657
	10 20 30 40 50 60 MVLQENGYGV EEDIPTLLMA ASSMDDLLAI TGFNTCLSIV FYSGGMINNA IASLRNVCIS 70 80 90 100 110 120 LLAGIVLGFF VRYFPSEDQK KITLKRGFLV LITFVSAVLG SQPIGLHGSG GLCTLVLHFI 130 140 150 160 170 180 EWTKWSQEKM KVQKIITNVW DIFQPLLFGL VGAEVSVSLL ESNIVGISVS TLSLALCVRI 190 200 210 LNIYLLMCFA GFSFKEKIFI ALAWMPKATV QVRTY

References

[1]

"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. , Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C. Nature 423:825-837(2003) [PubMed: 12815422] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC134882 Genomic DNA. No translation available.
IPI	IPI00737110.
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENST00000331172; ENSP00000331938; ENSG00000183704; Homo sapiens. [Genome view]
Organism-specific databases
GeneCards	GC0YM011956.
Phylogenomic databases
OMA	GEGRESH
OrthoDB	EOG9J402C
Gene expression databases
Genevestigator	A6NJY1.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

NHCL1_HUMAN

Accession

Primary (citable) accession number: A6NJY1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	July 22, 2008
Last modified:	November 24, 2009
This is version 14 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.