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Protein

UPF0573 protein C2orf70

Gene

C2orf70

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0573 protein C2orf70
Gene namesi
Name:C2orf70
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000173557.14
HGNCiHGNC:27938 C2orf70
neXtProtiNX_A6NJV1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000173557
PharmGKBiPA162379496

Polymorphism and mutation databases

BioMutaiC2orf70

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003322771 – 201UPF0573 protein C2orf70Add BLAST201

Proteomic databases

PaxDbiA6NJV1
PRIDEiA6NJV1

PTM databases

PhosphoSitePlusiA6NJV1

Expressioni

Gene expression databases

BgeeiENSG00000173557
CleanExiHS_C2orf70
ExpressionAtlasiA6NJV1 baseline and differential
GenevisibleiA6NJV1 HS

Organism-specific databases

HPAiHPA062453
HPA069279

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000332875

Structurei

3D structure databases

ProteinModelPortaliA6NJV1
SMRiA6NJV1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0573 family.Curated

Phylogenomic databases

eggNOGiENOG410IWU2 Eukaryota
ENOG4111R30 LUCA
GeneTreeiENSGT00390000018634
HOGENOMiHOG000007112
HOVERGENiHBG107581
InParanoidiA6NJV1
OMAiTTLKYFQ
OrthoDBiEOG091G0UVK
PhylomeDBiA6NJV1
TreeFamiTF329317

Family and domain databases

InterProiView protein in InterPro
IPR018902 UPF0573/UPF0605
PfamiView protein in Pfam
PF10629 DUF2475, 1 hit

Sequencei

Sequence statusi: Complete.

A6NJV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRSAGTLL TEFNAAYVPP GLMPGYQGHV PTVAFSFGAP YGTTTLKYFQ
60 70 80 90 100
DHRNRAMEKS HTPFSQGGHF PTIFSTNPNL LLMERASTRD RWLHKPSYTR
110 120 130 140 150
FNLDSHRSTE LTNFYQMVQQ HRKYYQDKTG TVPRVPYFAM PVREPERYPL
160 170 180 190 200
PTVLPPLCPK KKWHLLRLAP ENLKTYQTFP SGKRVSPQER KKRDCYFEFR

A
Length:201
Mass (Da):23,421
Last modified:July 24, 2007 - v1
Checksum:iDE69E9AFC9B7A4D4
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_04299866Q → H. Corresponds to variant dbSNP:rs13002673Ensembl.1
Natural variantiVAR_054056177Q → L. Corresponds to variant dbSNP:rs2272466Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015977 Genomic DNA No translation available.
AC108070 Genomic DNA No translation available.
CH471053 Genomic DNA Translation: EAX00681.1
CCDSiCCDS42661.1
RefSeqiNP_001098989.1, NM_001105519.2
UniGeneiHs.407083

Genome annotation databases

EnsembliENST00000329615; ENSP00000332875; ENSG00000173557
GeneIDi339778
KEGGihsa:339778
UCSCiuc010eyn.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCB070_HUMAN
AccessioniPrimary (citable) accession number: A6NJV1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 24, 2007
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome