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A6NIK2

- LR10B_HUMAN

UniProt

A6NIK2 - LR10B_HUMAN

Protein

Leucine-rich repeat-containing protein 10B

Gene

LRRC10B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 2 (02 Sep 2008)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucine-rich repeat-containing protein 10B
    Gene namesi
    Name:LRRC10B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:37215. LRRC10B.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA165543456.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 292292Leucine-rich repeat-containing protein 10BPRO_0000346162Add
    BLAST

    Proteomic databases

    PaxDbiA6NIK2.
    PRIDEiA6NIK2.

    PTM databases

    PhosphoSiteiA6NIK2.

    Expressioni

    Gene expression databases

    BgeeiA6NIK2.
    GenevestigatoriA6NIK2.

    Organism-specific databases

    HPAiHPA047619.

    Interactioni

    Protein-protein interaction databases

    BioGridi133444. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NIK2.
    SMRiA6NIK2. Positions 3-260.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati22 – 4322LRR 1Add
    BLAST
    Repeati45 – 6622LRR 2Add
    BLAST
    Repeati68 – 9023LRR 3Add
    BLAST
    Repeati91 – 11222LRR 4Add
    BLAST
    Repeati114 – 13623LRR 5Add
    BLAST
    Repeati137 – 15822LRR 6Add
    BLAST
    Repeati160 – 18122LRR 7Add
    BLAST
    Repeati183 – 20422LRR 8Add
    BLAST
    Repeati205 – 22622LRR 9Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi257 – 2626Poly-Glu

    Sequence similaritiesi

    Contains 9 LRR (leucine-rich) repeats.Curated

    Keywords - Domaini

    Leucine-rich repeat, Repeat

    Phylogenomic databases

    eggNOGiCOG4886.
    HOGENOMiHOG000113359.
    HOVERGENiHBG055066.
    InParanoidiA6NIK2.
    OMAiQKLYVSG.
    OrthoDBiEOG7BW0KV.
    PhylomeDBiA6NIK2.
    TreeFamiTF332853.

    Family and domain databases

    InterProiIPR001611. Leu-rich_rpt.
    [Graphical view]
    PfamiPF13504. LRR_7. 1 hit.
    PF13855. LRR_8. 1 hit.
    [Graphical view]
    PROSITEiPS51450. LRR. 7 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6NIK2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGIAESTPDE LPSDAEEQLR SGDQQLELSG RRLRRLPSAV CALSRLQKLY    50
    VSGTGLRELP EEIEELRELR ILALDFNKLE RLPDGLCRLP RLTRLYLGGN 100
    RLLALPADFA QLQSLRCLWI EGNFLRRFPR PLLRLVALQS LQMGDNRLRA 150
    LPAELPRMTG LRGLWLYGNR FEEFPPALLR MGRLHILDLD RNRLGGFPDL 200
    HPLRALRVFS YDHNPVTGPP RVADTVFLVG EGAVERMAER DEPTPRPPPR 250
    RPARAFEDEE EEDLLIGGAG SRALGAPGGS FRALEAAPGL GT 292
    Length:292
    Mass (Da):32,714
    Last modified:September 2, 2008 - v2
    Checksum:iC17ECE528B57EE39
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003108 Genomic DNA. No translation available.
    CCDSiCCDS44621.1.
    RefSeqiNP_001138549.1. NM_001145077.1.
    UniGeneiHs.441122.

    Genome annotation databases

    EnsembliENST00000378075; ENSP00000367315; ENSG00000204950.
    GeneIDi390205.
    KEGGihsa:390205.
    UCSCiuc010rlk.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003108 Genomic DNA. No translation available.
    CCDSi CCDS44621.1.
    RefSeqi NP_001138549.1. NM_001145077.1.
    UniGenei Hs.441122.

    3D structure databases

    ProteinModelPortali A6NIK2.
    SMRi A6NIK2. Positions 3-260.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 133444. 1 interaction.

    PTM databases

    PhosphoSitei A6NIK2.

    Proteomic databases

    PaxDbi A6NIK2.
    PRIDEi A6NIK2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000378075 ; ENSP00000367315 ; ENSG00000204950 .
    GeneIDi 390205.
    KEGGi hsa:390205.
    UCSCi uc010rlk.2. human.

    Organism-specific databases

    CTDi 390205.
    GeneCardsi GC11P061277.
    HGNCi HGNC:37215. LRRC10B.
    HPAi HPA047619.
    neXtProti NX_A6NIK2.
    PharmGKBi PA165543456.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG4886.
    HOGENOMi HOG000113359.
    HOVERGENi HBG055066.
    InParanoidi A6NIK2.
    OMAi QKLYVSG.
    OrthoDBi EOG7BW0KV.
    PhylomeDBi A6NIK2.
    TreeFami TF332853.

    Miscellaneous databases

    GenomeRNAii 390205.
    NextBioi 103522.
    PROi A6NIK2.

    Gene expression databases

    Bgeei A6NIK2.
    Genevestigatori A6NIK2.

    Family and domain databases

    InterProi IPR001611. Leu-rich_rpt.
    [Graphical view ]
    Pfami PF13504. LRR_7. 1 hit.
    PF13855. LRR_8. 1 hit.
    [Graphical view ]
    PROSITEi PS51450. LRR. 7 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiLR10B_HUMAN
    AccessioniPrimary (citable) accession number: A6NIK2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 2, 2008
    Last sequence update: September 2, 2008
    Last modified: October 1, 2014
    This is version 53 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3