Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A6NIK2 (LR10B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Leucine-rich repeat-containing protein 10B
Gene names
Name:LRRC10B
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Sequence similarities

Contains 9 LRR (leucine-rich) repeats.

Ontologies

Keywords
   DomainLeucine-rich repeat
Repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Leucine-rich repeat-containing protein 10B
PRO_0000346162

Regions

Repeat22 – 4322LRR 1
Repeat45 – 6622LRR 2
Repeat68 – 9023LRR 3
Repeat91 – 11222LRR 4
Repeat114 – 13623LRR 5
Repeat137 – 15822LRR 6
Repeat160 – 18122LRR 7
Repeat183 – 20422LRR 8
Repeat205 – 22622LRR 9
Compositional bias257 – 2626Poly-Glu

Sequences

Sequence LengthMass (Da)Tools
A6NIK2 [UniParc].

Last modified September 2, 2008. Version 2.
Checksum: C17ECE528B57EE39

FASTA29232,714
        10         20         30         40         50         60 
MGIAESTPDE LPSDAEEQLR SGDQQLELSG RRLRRLPSAV CALSRLQKLY VSGTGLRELP 

        70         80         90        100        110        120 
EEIEELRELR ILALDFNKLE RLPDGLCRLP RLTRLYLGGN RLLALPADFA QLQSLRCLWI 

       130        140        150        160        170        180 
EGNFLRRFPR PLLRLVALQS LQMGDNRLRA LPAELPRMTG LRGLWLYGNR FEEFPPALLR 

       190        200        210        220        230        240 
MGRLHILDLD RNRLGGFPDL HPLRALRVFS YDHNPVTGPP RVADTVFLVG EGAVERMAER 

       250        260        270        280        290 
DEPTPRPPPR RPARAFEDEE EEDLLIGGAG SRALGAPGGS FRALEAAPGL GT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP003108 Genomic DNA. No translation available.
CCDSCCDS44621.1.
RefSeqNP_001138549.1. NM_001145077.1.
UniGeneHs.441122.

3D structure databases

ProteinModelPortalA6NIK2.
SMRA6NIK2. Positions 3-260.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid133444. 1 interaction.

PTM databases

PhosphoSiteA6NIK2.

Proteomic databases

PaxDbA6NIK2.
PRIDEA6NIK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000378075; ENSP00000367315; ENSG00000204950.
GeneID390205.
KEGGhsa:390205.
UCSCuc010rlk.2. human.

Organism-specific databases

CTD390205.
GeneCardsGC11P061277.
HGNCHGNC:37215. LRRC10B.
HPAHPA047619.
neXtProtNX_A6NIK2.
PharmGKBPA165543456.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG4886.
HOGENOMHOG000113359.
HOVERGENHBG055066.
InParanoidA6NIK2.
OMAQKLYVSG.
OrthoDBEOG7BW0KV.
PhylomeDBA6NIK2.
TreeFamTF332853.

Gene expression databases

BgeeA6NIK2.
GenevestigatorA6NIK2.

Family and domain databases

InterProIPR001611. Leu-rich_rpt.
[Graphical view]
PfamPF13504. LRR_7. 1 hit.
PF13855. LRR_8. 1 hit.
[Graphical view]
PROSITEPS51450. LRR. 7 hits.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi390205.
NextBio103522.
PROA6NIK2.

Entry information

Entry nameLR10B_HUMAN
AccessionPrimary (citable) accession number: A6NIK2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 9, 2014
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM