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Protein

Putative POTE ankyrin domain family member M

Gene

POTEM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Putative POTE ankyrin domain family member M
Gene namesi
Name:POTEM
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:37096. POTEM.

Pathology & Biotechi

Organism-specific databases

DisGeNETi641455.
OpenTargetsiENSG00000222036.
PharmGKBiPA165479276.

Polymorphism and mutation databases

BioMutaiPOTEM.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003321501 – 508Putative POTE ankyrin domain family member MAdd BLAST508

Proteomic databases

MaxQBiA6NI47.
PaxDbiA6NI47.
PRIDEiA6NI47.

PTM databases

iPTMnetiA6NI47.
PhosphoSitePlusiA6NI47.

Expressioni

Gene expression databases

BgeeiENSG00000187537.
ExpressionAtlasiA6NI47. baseline and differential.

Organism-specific databases

HPAiHPA042822.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000452296.

Structurei

3D structure databases

ProteinModelPortaliA6NI47.
SMRiA6NI47.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati172 – 201ANK 1Add BLAST30
Repeati205 – 234ANK 2Add BLAST30
Repeati238 – 267ANK 3Add BLAST30
Repeati271 – 300ANK 4Add BLAST30
Repeati304 – 333ANK 5Add BLAST30

Sequence similaritiesi

Belongs to the POTE family.Curated
Contains 5 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiENOG410ITJG. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00560000076605.
HOVERGENiHBG050513.
InParanoidiA6NI47.
KOiK17299.
OMAiCCESASI.
OrthoDBiEOG091G077A.
PhylomeDBiA6NI47.
TreeFamiTF337879.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NI47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAEAGSMPA ASSVKKPFGL RSKMGKWCRH CFPWCRGSGK SNVGTSGDHD
60 70 80 90 100
DSAMKTLRSK MGKWCRHCFP WCRGSGKSNV GTSGDHDDSA MKTLRSKMGK
110 120 130 140 150
WCCHCFPCCR GSGKSKVGPW GDYDDSAFME PRYHVRREDL DKLHRAAWWG
160 170 180 190 200
KVPRKDLIVM LKDTDMNKKD KQKRTALHLA SANGNSEVVK LLLDRRCQLN
210 220 230 240 250
ILDNKKRTAL TKAVQCQEDE CALMLLEHGT DPNIPDEYGN TALHYAIYNE
260 270 280 290 300
DKLMAKALLL YGADIESKNK HGLTPLLLGV HEQKQQVVKF LIKKKANLNA
310 320 330 340 350
LDRYGRTVLI LAVCCGSASI VSLLLEQNID VSSQDLSGQT AREYAVSSRH
360 370 380 390 400
NVICQLLSDY KEKQILKVSS ENSNPEQDLK LTSEEESQRL KGSENSQPEE
410 420 430 440 450
MSQEPEINKG GDRKVEEEMK KHGSTHMGFP ENLPNGATAD NGDDGLIPPR
460 470 480 490 500
KSRTPESQQF PDTENEQYHS DEQNDTQKQL SEEQNTGILQ DEILIHEEKQ

IEVAENEF
Length:508
Mass (Da):57,067
Last modified:January 15, 2008 - v2
Checksum:i786971B0BAFAC804
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589182 Genomic DNA. No translation available.
AL929601 Genomic DNA. No translation available.
CCDSiCCDS73609.1.
RefSeqiNP_001138914.1. NM_001145442.1.
UniGeneiHs.654289.

Genome annotation databases

EnsembliENST00000547889; ENSP00000448062; ENSG00000222036.
GeneIDi641455.
KEGGihsa:641455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589182 Genomic DNA. No translation available.
AL929601 Genomic DNA. No translation available.
CCDSiCCDS73609.1.
RefSeqiNP_001138914.1. NM_001145442.1.
UniGeneiHs.654289.

3D structure databases

ProteinModelPortaliA6NI47.
SMRiA6NI47.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000452296.

PTM databases

iPTMnetiA6NI47.
PhosphoSitePlusiA6NI47.

Polymorphism and mutation databases

BioMutaiPOTEM.

Proteomic databases

MaxQBiA6NI47.
PaxDbiA6NI47.
PRIDEiA6NI47.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000547889; ENSP00000448062; ENSG00000222036.
GeneIDi641455.
KEGGihsa:641455.

Organism-specific databases

CTDi641455.
DisGeNETi641455.
GeneCardsiPOTEM.
HGNCiHGNC:37096. POTEM.
HPAiHPA042822.
neXtProtiNX_A6NI47.
OpenTargetsiENSG00000222036.
PharmGKBiPA165479276.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ITJG. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00560000076605.
HOVERGENiHBG050513.
InParanoidiA6NI47.
KOiK17299.
OMAiCCESASI.
OrthoDBiEOG091G077A.
PhylomeDBiA6NI47.
TreeFamiTF337879.

Miscellaneous databases

GenomeRNAii641455.
PROiA6NI47.

Gene expression databases

BgeeiENSG00000187537.
ExpressionAtlasiA6NI47. baseline and differential.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPOTEM_HUMAN
AccessioniPrimary (citable) accession number: A6NI47
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: January 15, 2008
Last modified: November 2, 2016
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.