Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Roquin-2

Gene

RC3H2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri410 – 438C3H1-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Roquin-2Imported
Gene namesi
Name:RC3H2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000056586.15.
HGNCiHGNC:21461. RC3H2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000056586.

PTM / Processingi

Proteomic databases

MaxQBiA6NHN2.
PaxDbiA6NHN2.
PeptideAtlasiA6NHN2.
PRIDEiA6NHN2.

Expressioni

Gene expression databases

BgeeiENSG00000056586.
ExpressionAtlasiA6NHN2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA6NHN2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 54RING-typeInterPro annotationAdd BLAST41
Domaini410 – 438C3H1-typeInterPro annotationAdd BLAST29

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri410 – 438C3H1-typePROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3161. Eukaryota.
ENOG410YWQD. LUCA.
GeneTreeiENSGT00390000004311.
HOGENOMiHOG000293270.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
4.10.1000.10. 1 hit.
InterProiView protein in InterPro
IPR032670. RC3H2.
IPR027370. Znf-RING_LisH.
IPR000571. Znf_CCCH.
IPR036855. Znf_CCCH_sf.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
PANTHERiPTHR13139:SF2. PTHR13139:SF2. 1 hit.
PfamiView protein in Pfam
PF00642. zf-CCCH. 1 hit.
PF13445. zf-RING_UBOX. 1 hit.
SMARTiView protein in SMART
SM00184. RING. 1 hit.
SM00356. ZnF_C3H1. 1 hit.
SUPFAMiSSF90229. SSF90229. 1 hit.
PROSITEiView protein in PROSITE
PS50103. ZF_C3H1. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NHN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVQAAQWTE FLSCPICYNE FDENVHKPIS LGCSHTVCKT CLNKLHRKAC
60 70 80 90 100
PFDQTAINTD IDVLPVNFAL LQLVGAQVPD HQSIKLSNLG ENKHYEVAKK
110 120 130 140 150
CVEDLALYLK PLSGGKGVAS LNQSALSRPM QRKLVTLVNC QLVEEEGRVR
160 170 180 190 200
AMRAARSLGE RTVTELILQH QNPQQLSANL WAAVRARGCQ FLGPAMQEEA
210 220 230 240 250
LKLVLLALED GSALSRKVLV LFVVQRLEPR FPQASKTSIG HVVQLLYRAS
260 270 280 290 300
CFKVTKRDED SSLMQLKEEF RSYEALRREH DAQIVHIAME AGLRISPEQW
310 320 330 340 350
SSLLYGDLAH KSHMQSIIDK LQSPESFAKS VQELTIVLQR TGDPANLNRL
360 370 380 390 400
RPHLELLANI DPNPDAVSPT WEQLENAMVA VKTVVHGLVD FIQNYSRKGH
410 420 430 440 450
ETPQPQPNSK YKTSMCRDLR QQGGCPRGTN CTFAHSQEEL EKCNPRGLYL
460 470 480 490 500
HCCLLSSVAS LGTVHNELYK QQHCDREKIS VCAVKRAETC FSSQFFSPLE

VPREED
Length:506
Mass (Da):56,823
Last modified:January 15, 2008 - v2
Checksum:iF2915DA0B8C97C9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007066 Genomic DNA. No translation available.
AL359512 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000335387; ENSP00000335150; ENSG00000056586.
UCSCiuc064vno.1. human.

Similar proteinsi

Entry informationi

Entry nameiA6NHN2_HUMAN
AccessioniPrimary (citable) accession number: A6NHN2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: January 15, 2008
Last modified: October 25, 2017
This is version 84 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported