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Protein
Submitted name:

Fibronectin type 3 and ankyrin repeat domains protein 1

Gene

FANK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Fibronectin type 3 and ankyrin repeat domains protein 1Imported
Submitted name:
Fibronectin type III and ankyrin repeat domains 1, isoform CRA_dImported
Gene namesi
Name:FANK1Imported
ORF Names:hCG_40943Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000203780.10
HGNCiHGNC:23527 FANK1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203780

PTM / Processingi

Proteomic databases

PeptideAtlasiA6NH44
PRIDEiA6NH44

Expressioni

Gene expression databases

BgeeiENSG00000203780
ExpressionAtlasiA6NH44 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 102Fibronectin type-IIIInterPro annotationAdd BLAST101
Domaini108 – 324ANK_REP_REGIONInterPro annotationAdd BLAST217
Repeati137 – 169ANKPROSITE-ProRule annotationAdd BLAST33
Repeati170 – 202ANKPROSITE-ProRule annotationAdd BLAST33
Repeati203 – 235ANKPROSITE-ProRule annotationAdd BLAST33
Repeati237 – 270ANKPROSITE-ProRule annotationAdd BLAST34
Repeati271 – 303ANKPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00530000063369
HOGENOMiHOG000293255
HOVERGENiHBG051552

Family and domain databases

CDDicd00204 ANK, 2 hits
cd00063 FN3, 1 hit
Gene3Di1.25.40.20, 2 hits
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SM00060 FN3, 1 hit
SUPFAMiSSF48403 SSF48403, 1 hit
SSF49265 SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits
PS50853 FN3, 1 hit

Sequencei

Sequence statusi: Complete.

A6NH44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPSKPHPPV VGKVTHHSIE LYWDLEKKAK RQGPQEQWFR FSIEEEDPKM
60 70 80 90 100
HTYGIIYTGY ATKHVVEGLE PRTLYRFRLK VTSPSGECEY SPLVSVSTTR
110 120 130 140 150
EPISSEHLHR AVSVNDEDLL VRILQGGRVK VDVPNKFGFT ALMVAAQKGY
160 170 180 190 200
TRLVKILVSN GTDVNLKNGS GKDSLMLACY AGHLDVVKYL RRHGASWQAR
210 220 230 240 250
DLGGCTALHW AADGGHCSVI EWMIKDGCEV DVVDTGSGWT PLMRVSAVSG
260 270 280 290 300
NQRVASLLID AGANVNVKDR NGKTPLMVAV LNNHEELVQL LLDKGADASV
310 320 330
KNEFGKGVLE MARVFDRQSV VSLLEERKKK QRPKKSCVC
Length:339
Mass (Da):37,614
Last modified:July 24, 2007 - v1
Checksum:i7849EFF868C3C1B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063963 Genomic DNA No translation available.
AL360176 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49214.1
RefSeqiXP_016872410.1, XM_017016921.1
UniGeneiHs.352591

Genome annotation databases

EnsembliENST00000368695; ENSP00000357684; ENSG00000203780
GeneIDi92565
UCSCiuc057wsy.1 human

Similar proteinsi

Entry informationi

Entry nameiA6NH44_HUMAN
AccessioniPrimary (citable) accession number: A6NH44
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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