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Protein
Submitted name:

Fibronectin type 3 and ankyrin repeat domains protein 1

Gene

FANK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Fibronectin type 3 and ankyrin repeat domains protein 1Imported
Submitted name:
Fibronectin type III and ankyrin repeat domains 1, isoform CRA_dImported
Gene namesi
Name:FANK1Imported
ORF Names:hCG_40943Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:23527. FANK1.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203780.

Expressioni

Gene expression databases

BgeeiENSG00000203780.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000357682.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 102Fibronectin type-IIIInterPro annotationAdd BLAST101
Domaini108 – 324ANK_REP_REGIONInterPro annotationAdd BLAST217
Repeati137 – 169ANKPROSITE-ProRule annotationAdd BLAST33
Repeati170 – 202ANKPROSITE-ProRule annotationAdd BLAST33
Repeati203 – 235ANKPROSITE-ProRule annotationAdd BLAST33
Repeati237 – 270ANKPROSITE-ProRule annotationAdd BLAST34
Repeati271 – 303ANKPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129724.
HOGENOMiHOG000293255.
HOVERGENiHBG051552.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di1.25.40.20. 1 hit.
2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 6 hits.
SM00060. FN3. 1 hit.
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50853. FN3. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NH44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPSKPHPPV VGKVTHHSIE LYWDLEKKAK RQGPQEQWFR FSIEEEDPKM
60 70 80 90 100
HTYGIIYTGY ATKHVVEGLE PRTLYRFRLK VTSPSGECEY SPLVSVSTTR
110 120 130 140 150
EPISSEHLHR AVSVNDEDLL VRILQGGRVK VDVPNKFGFT ALMVAAQKGY
160 170 180 190 200
TRLVKILVSN GTDVNLKNGS GKDSLMLACY AGHLDVVKYL RRHGASWQAR
210 220 230 240 250
DLGGCTALHW AADGGHCSVI EWMIKDGCEV DVVDTGSGWT PLMRVSAVSG
260 270 280 290 300
NQRVASLLID AGANVNVKDR NGKTPLMVAV LNNHEELVQL LLDKGADASV
310 320 330
KNEFGKGVLE MARVFDRQSV VSLLEERKKK QRPKKSCVC
Length:339
Mass (Da):37,614
Last modified:July 24, 2007 - v1
Checksum:i7849EFF868C3C1B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063963 Genomic DNA. No translation available.
AL360176 Genomic DNA. No translation available.
CH471066 Genomic DNA. Translation: EAW49214.1.
RefSeqiXP_016872410.1. XM_017016921.1.
UniGeneiHs.352591.

Genome annotation databases

EnsembliENST00000368695; ENSP00000357684; ENSG00000203780.
GeneIDi92565.
UCSCiuc057wsy.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC063963 Genomic DNA. No translation available.
AL360176 Genomic DNA. No translation available.
CH471066 Genomic DNA. Translation: EAW49214.1.
RefSeqiXP_016872410.1. XM_017016921.1.
UniGeneiHs.352591.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000357682.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000368695; ENSP00000357684; ENSG00000203780.
GeneIDi92565.
UCSCiuc057wsy.1. human.

Organism-specific databases

CTDi92565.
HGNCiHGNC:23527. FANK1.
OpenTargetsiENSG00000203780.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000129724.
HOGENOMiHOG000293255.
HOVERGENiHBG051552.

Miscellaneous databases

ChiTaRSiFANK1. human.
GenomeRNAii92565.

Gene expression databases

BgeeiENSG00000203780.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di1.25.40.20. 1 hit.
2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 6 hits.
SM00060. FN3. 1 hit.
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50853. FN3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA6NH44_HUMAN
AccessioniPrimary (citable) accession number: A6NH44
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: March 15, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.