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Protein

Glycolipid transfer protein domain-containing protein 2

Gene

GLTPD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciZFISH:G66-32663-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycolipid transfer protein domain-containing protein 2
Gene namesi
Name:GLTPD2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:33756. GLTPD2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182327.
PharmGKBiPA162389864.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003171621 – 291Glycolipid transfer protein domain-containing protein 2Add BLAST291

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi276N-linked (GlcNAc...)1 Publication1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiA6NH11.
PaxDbiA6NH11.
PRIDEiA6NH11.

PTM databases

iPTMnetiA6NH11.
PhosphoSitePlusiA6NH11.

Expressioni

Gene expression databases

BgeeiENSG00000182327.
CleanExiHS_GLTPD2.
GenevisibleiA6NH11. HS.

Organism-specific databases

HPAiHPA058295.

Interactioni

Protein-protein interaction databases

IntActiA6NH11. 1 interactor.
STRINGi9606.ENSP00000328070.

Structurei

3D structure databases

ProteinModelPortaliA6NH11.
SMRiA6NH11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GLTP family.Curated

Phylogenomic databases

eggNOGiKOG4189. Eukaryota.
ENOG4111NKT. LUCA.
GeneTreeiENSGT00530000063818.
HOGENOMiHOG000046738.
HOVERGENiHBG100515.
InParanoidiA6NH11.
OMAiGRMMRPF.
OrthoDBiEOG091G0LIV.
PhylomeDBiA6NH11.
TreeFamiTF316097.

Family and domain databases

Gene3Di1.10.3520.10. 1 hit.
InterProiIPR014830. Glycolipid_transfer_prot_dom.
[Graphical view]
PfamiPF08718. GLTP. 1 hit.
[Graphical view]
SUPFAMiSSF110004. SSF110004. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NH11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVAARPPAL RHWFSHSIPL AIFALLLLYL SVRSLGARSG CGPRAQPCVP
60 70 80 90 100
GETAPFQVRQ ESGTLEAPER KQPPCLGPRG MLGRMMRRFH ASLKPEGDVG
110 120 130 140 150
LSPYLAGWRA LVEFLTPLGS VFAFATREAF TKVTDLEARV HGPDAEHYWS
160 170 180 190 200
LVAMAAWERR AGLLEQPGAA PRDPTRSSGS RTLLLLHRAL RWSQLCLHRV
210 220 230 240 250
ATGALGGPDA GVQCSDAYRA ALGPHHPWLV RQTARLAFLA FPGRRRLLEL
260 270 280 290
ACPGATEAEA RAALVRAAGT LEDVYNRTQS LLAERGLLQL A
Length:291
Mass (Da):31,642
Last modified:May 31, 2011 - v2
Checksum:i589565F42C5AA13F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti152V → A in AAI50537 (PubMed:15489334).Curated1
Sequence conflicti209D → E in AAI50537 (PubMed:15489334).Curated1
Sequence conflicti265V → L in AAI50537 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109333 Genomic DNA. No translation available.
BC150536 mRNA. Translation: AAI50537.1.
CCDSiCCDS32534.1.
UniGeneiHs.131035.

Genome annotation databases

EnsembliENST00000331264; ENSP00000328070; ENSG00000182327.
UCSCiuc002fza.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109333 Genomic DNA. No translation available.
BC150536 mRNA. Translation: AAI50537.1.
CCDSiCCDS32534.1.
UniGeneiHs.131035.

3D structure databases

ProteinModelPortaliA6NH11.
SMRiA6NH11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA6NH11. 1 interactor.
STRINGi9606.ENSP00000328070.

PTM databases

iPTMnetiA6NH11.
PhosphoSitePlusiA6NH11.

Proteomic databases

MaxQBiA6NH11.
PaxDbiA6NH11.
PRIDEiA6NH11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000331264; ENSP00000328070; ENSG00000182327.
UCSCiuc002fza.3. human.

Organism-specific databases

GeneCardsiGLTPD2.
H-InvDBHIX0013449.
HIX0135615.
HGNCiHGNC:33756. GLTPD2.
HPAiHPA058295.
neXtProtiNX_A6NH11.
OpenTargetsiENSG00000182327.
PharmGKBiPA162389864.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4189. Eukaryota.
ENOG4111NKT. LUCA.
GeneTreeiENSGT00530000063818.
HOGENOMiHOG000046738.
HOVERGENiHBG100515.
InParanoidiA6NH11.
OMAiGRMMRPF.
OrthoDBiEOG091G0LIV.
PhylomeDBiA6NH11.
TreeFamiTF316097.

Enzyme and pathway databases

BioCyciZFISH:G66-32663-MONOMER.

Miscellaneous databases

PROiA6NH11.

Gene expression databases

BgeeiENSG00000182327.
CleanExiHS_GLTPD2.
GenevisibleiA6NH11. HS.

Family and domain databases

Gene3Di1.10.3520.10. 1 hit.
InterProiIPR014830. Glycolipid_transfer_prot_dom.
[Graphical view]
PfamiPF08718. GLTP. 1 hit.
[Graphical view]
SUPFAMiSSF110004. SSF110004. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLTD2_HUMAN
AccessioniPrimary (citable) accession number: A6NH11
Secondary accession number(s): A7E2T2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 31, 2011
Last modified: November 2, 2016
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.