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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2 J2

Gene

UBE2J2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei42Glycyl thioester intermediatePROSITE-ProRule annotation1

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2 J2Imported
Submitted name:
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), isoform CRA_eImported
Gene namesi
Name:UBE2J2Imported
ORF Names:hCG_20420Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000160087.20
HGNCiHGNC:19268 UBE2J2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei176 – 197HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134882268

PTM / Processingi

Proteomic databases

MaxQBiA6NGS0
PeptideAtlasiA6NGS0

Expressioni

Gene expression databases

BgeeiENSG00000160087

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000383719

Structurei

3D structure databases

SMRiA6NGS0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 76UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0894 Eukaryota
ENOG410Z0AN LUCA
GeneTreeiENSGT00530000063379
HOGENOMiHOG000170330
HOVERGENiHBG058434

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

A6NGS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPYEGGYYH GKLIFPREFP FKPPSIYMIT PNGRFKCNTR LCLSITDFHP
60 70 80 90 100
DTWNPAWSVS TILTGLLSFM VEKGPTLGSI ETSDFTKRQL AVQSLAFNLK
110 120 130 140 150
DKVFCELFPE VVEEIKQKQK AQDELSSRPQ TLPLPDVVPD GETHLVQNGI
160 170 180 190 200
QLLNGHAPGA VPNLAGLQQA NRHHGLLGGA LANLFVIVGF AAFAYTVKYV

LRSIAQE
Length:207
Mass (Da):22,943
Last modified:July 24, 2007 - v1
Checksum:i4B3050A60503B8F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162741 Genomic DNA No translation available.
KF495840 Genomic DNA No translation available.
CH471183 Genomic DNA Translation: EAW56262.1
CH471183 Genomic DNA Translation: EAW56266.1
RefSeqiNP_919439.1, NM_194457.1
NP_919440.1, NM_194458.1
XP_016855728.1, XM_017000239.1
UniGeneiHs.191987

Genome annotation databases

EnsembliENST00000347370; ENSP00000344857; ENSG00000160087
ENST00000400929; ENSP00000383718; ENSG00000160087
GeneIDi118424
UCSCiuc001adq.4 human

Similar proteinsi

Entry informationi

Entry nameiA6NGS0_HUMAN
AccessioniPrimary (citable) accession number: A6NGS0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: April 25, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health