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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2 J2

Gene

UBE2J2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2 J2Imported
Submitted name:
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), isoform CRA_eImported
Gene namesi
Name:UBE2J2Imported
ORF Names:hCG_20420Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:19268. UBE2J2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei176 – 197HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000160087.
PharmGKBiPA134882268.

PTM / Processingi

Proteomic databases

MaxQBiA6NGS0.
PeptideAtlasiA6NGS0.
PRIDEiA6NGS0.

Expressioni

Gene expression databases

BgeeiENSG00000160087.
ExpressionAtlasiA6NGS0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000383719.

Structurei

3D structure databases

ProteinModelPortaliA6NGS0.
SMRiA6NGS0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 76UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST76

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0894. Eukaryota.
ENOG410Z0AN. LUCA.
GeneTreeiENSGT00530000063379.
HOGENOMiHOG000170330.
HOVERGENiHBG058434.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NGS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPYEGGYYH GKLIFPREFP FKPPSIYMIT PNGRFKCNTR LCLSITDFHP
60 70 80 90 100
DTWNPAWSVS TILTGLLSFM VEKGPTLGSI ETSDFTKRQL AVQSLAFNLK
110 120 130 140 150
DKVFCELFPE VVEEIKQKQK AQDELSSRPQ TLPLPDVVPD GETHLVQNGI
160 170 180 190 200
QLLNGHAPGA VPNLAGLQQA NRHHGLLGGA LANLFVIVGF AAFAYTVKYV

LRSIAQE
Length:207
Mass (Da):22,943
Last modified:July 24, 2007 - v1
Checksum:i4B3050A60503B8F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162741 Genomic DNA. No translation available.
KF495840 Genomic DNA. No translation available.
CH471183 Genomic DNA. Translation: EAW56262.1.
CH471183 Genomic DNA. Translation: EAW56266.1.
RefSeqiNP_919439.1. NM_194457.1.
NP_919440.1. NM_194458.1.
XP_016855728.1. XM_017000239.1.
UniGeneiHs.191987.

Genome annotation databases

EnsembliENST00000347370; ENSP00000344857; ENSG00000160087.
ENST00000400929; ENSP00000383718; ENSG00000160087.
GeneIDi118424.
UCSCiuc001adq.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162741 Genomic DNA. No translation available.
KF495840 Genomic DNA. No translation available.
CH471183 Genomic DNA. Translation: EAW56262.1.
CH471183 Genomic DNA. Translation: EAW56266.1.
RefSeqiNP_919439.1. NM_194457.1.
NP_919440.1. NM_194458.1.
XP_016855728.1. XM_017000239.1.
UniGeneiHs.191987.

3D structure databases

ProteinModelPortaliA6NGS0.
SMRiA6NGS0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000383719.

Proteomic databases

MaxQBiA6NGS0.
PeptideAtlasiA6NGS0.
PRIDEiA6NGS0.

Protocols and materials databases

DNASUi118424.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000347370; ENSP00000344857; ENSG00000160087.
ENST00000400929; ENSP00000383718; ENSG00000160087.
GeneIDi118424.
UCSCiuc001adq.4. human.

Organism-specific databases

CTDi118424.
HGNCiHGNC:19268. UBE2J2.
OpenTargetsiENSG00000160087.
PharmGKBiPA134882268.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0894. Eukaryota.
ENOG410Z0AN. LUCA.
GeneTreeiENSGT00530000063379.
HOGENOMiHOG000170330.
HOVERGENiHBG058434.

Miscellaneous databases

ChiTaRSiUBE2J2. human.
GenomeRNAii118424.

Gene expression databases

BgeeiENSG00000160087.
ExpressionAtlasiA6NGS0. baseline and differential.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA6NGS0_HUMAN
AccessioniPrimary (citable) accession number: A6NGS0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.