A6NGH8 (ANR61_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ankyrin repeat domain-containing protein 61

Gene names

Name:

ANKRD61

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 8 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 418	418	Ankyrin repeat domain-containing protein 61		PRO_0000328762
Regions
	Repeat	27 – 57	31	ANK 1
	Repeat	75 – 104	30	ANK 2
	Repeat	132 – 161	30	ANK 3
	Repeat	167 – 196	30	ANK 4
	Repeat	200 – 229	30	ANK 5
	Repeat	234 – 273	40	ANK 6
	Repeat	277 – 306	30	ANK 7
	Repeat	310 – 343	34	ANK 8

Sequences

	Sequence		Length	Mass (Da)
	A6NGH8 [UniParc]. Last modified July 22, 2008. Version 2. Checksum: DD079DA78FFE4613	FASTA	418	46,141
	10 20 30 40 50 60 MGNITRKGSR DLVVDSAKSL EDGPSAALHS KLYEAIMRED CTTIEVLLRN HPVNQPITIL 70 80 90 100 110 120 PNSASNRLLL TQPTESIIPI HLAAKYHKAQ SLLCLLRHGA DPEVRDTTGL TTLNLMLLHW 130 140 150 160 170 180 PVTSTTWAKP GNRTHRILTD IQNSSITCLR ILCAHGAQVN TQGEISNKRS PLHLAIAYGC 190 200 210 220 230 240 YPVLSILTQN GADVNAINEA SMTPLHMAAN MLNKEMMETL IAYGANVNCA VSSTGNTPLK 250 260 270 280 290 300 LAVCTASSKA GRLLGAGVSC IRLLLTHGAK VNAQDYKGQT AIHEACFGGR EAIINLLLEF 310 320 330 340 350 360 EANVNILTRN GESPIYMYLQ RSCNVRDTAL LARLLYHTYP LRMTNNQGIL PAGIMLPEFR 370 380 390 400 410 LLRDTLIKQS QKPLSLQGIC KRNIRNIYGE KYKQHLKQFL PVTIWNSVYC CYDLAYTS

References

[1]

"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC005995 Genomic DNA. No translation available.
IPI	IPI00062735.
RefSeq	NP_001258629.1. NM_001271700.1.
3D structure databases
ProteinModelPortal	A6NGH8.
ModBase	Search...
PTM databases
PhosphoSite	A6NGH8.
Proteomic databases
PaxDb	A6NGH8.
PRIDE	A6NGH8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000409061; ENSP00000386502; ENSG00000157999.
GeneID	100310846.
KEGG	hsa:100310846.
Organism-specific databases
CTD	100310846.
GeneCards	GC07P006071.
HGNC	HGNC:22467. ANKRD61.
HPA	HPA029511.
neXtProt	NX_A6NGH8.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0666.
HOGENOM	HOG000155553.
InParanoid	A6NGH8.
OMA	HEACFGG.
OrthoDB	EOG4PC9S4.
Gene expression databases
Bgee	A6NGH8.
Genevestigator	A6NGH8.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. [Graphical view]
Pfam	PF00023. Ank. 1 hit. PF12796. Ank_2. 2 hits. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 5 hits. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 5 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ANR61_HUMAN

Accession

Primary (citable) accession number: A6NGH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	July 22, 2008
Last modified:	May 1, 2013
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.