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Protein

Ankyrin repeat domain-containing protein 61

Gene

ANKRD61

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-32858-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 61
Gene namesi
Name:ANKRD61
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:22467. ANKRD61.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157999.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003287621 – 418Ankyrin repeat domain-containing protein 61Add BLAST418

Proteomic databases

PaxDbiA6NGH8.
PRIDEiA6NGH8.

PTM databases

PhosphoSitePlusiA6NGH8.

Expressioni

Gene expression databases

BgeeiENSG00000157999.

Organism-specific databases

HPAiHPA029511.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000386502.

Structurei

3D structure databases

ProteinModelPortaliA6NGH8.
SMRiA6NGH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati27 – 57ANK 1Add BLAST31
Repeati75 – 104ANK 2Add BLAST30
Repeati132 – 161ANK 3Add BLAST30
Repeati167 – 196ANK 4Add BLAST30
Repeati200 – 229ANK 5Add BLAST30
Repeati234 – 273ANK 6Add BLAST40
Repeati277 – 306ANK 7Add BLAST30
Repeati310 – 343ANK 8Add BLAST34

Sequence similaritiesi

Contains 8 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000130004.
HOGENOMiHOG000155553.
InParanoidiA6NGH8.
OMAiHEACFGG.
OrthoDBiEOG091G07YZ.
PhylomeDBiA6NGH8.
TreeFamiTF352214.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NGH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNITRKGSR DLVVDSAKSL EDGPSAALHS KLYEAIMRED CTTIEVLLRN
60 70 80 90 100
HPVNQPITIL PNSASNRLLL TQPTESIIPI HLAAKYHKAQ SLLCLLRHGA
110 120 130 140 150
DPEVRDTTGL TTLNLMLLHW PVTSTTWAKP GNRTHRILTD IQNSSITCLR
160 170 180 190 200
ILCAHGAQVN TQGEISNKRS PLHLAIAYGC YPVLSILTQN GADVNAINEA
210 220 230 240 250
SMTPLHMAAN MLNKEMMETL IAYGANVNCA VSSTGNTPLK LAVCTASSKA
260 270 280 290 300
GRLLGAGVSC IRLLLTHGAK VNAQDYKGQT AIHEACFGGR EAIINLLLEF
310 320 330 340 350
EANVNILTRN GESPIYMYLQ RSCNVRDTAL LARLLYHTYP LRMTNNQGIL
360 370 380 390 400
PAGIMLPEFR LLRDTLIKQS QKPLSLQGIC KRNIRNIYGE KYKQHLKQFL
410
PVTIWNSVYC CYDLAYTS
Length:418
Mass (Da):46,141
Last modified:July 22, 2008 - v2
Checksum:iDD079DA78FFE4613
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005995 Genomic DNA. No translation available.
CCDSiCCDS64590.1.
RefSeqiNP_001258629.1. NM_001271700.1.
UniGeneiHs.744468.

Genome annotation databases

EnsembliENST00000409061; ENSP00000386502; ENSG00000157999.
GeneIDi100310846.
KEGGihsa:100310846.
UCSCiuc031swn.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005995 Genomic DNA. No translation available.
CCDSiCCDS64590.1.
RefSeqiNP_001258629.1. NM_001271700.1.
UniGeneiHs.744468.

3D structure databases

ProteinModelPortaliA6NGH8.
SMRiA6NGH8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000386502.

PTM databases

PhosphoSitePlusiA6NGH8.

Proteomic databases

PaxDbiA6NGH8.
PRIDEiA6NGH8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409061; ENSP00000386502; ENSG00000157999.
GeneIDi100310846.
KEGGihsa:100310846.
UCSCiuc031swn.2. human.

Organism-specific databases

CTDi100310846.
GeneCardsiANKRD61.
HGNCiHGNC:22467. ANKRD61.
HPAiHPA029511.
neXtProtiNX_A6NGH8.
OpenTargetsiENSG00000157999.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4177. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00840000130004.
HOGENOMiHOG000155553.
InParanoidiA6NGH8.
OMAiHEACFGG.
OrthoDBiEOG091G07YZ.
PhylomeDBiA6NGH8.
TreeFamiTF352214.

Enzyme and pathway databases

BioCyciZFISH:G66-32858-MONOMER.

Miscellaneous databases

GenomeRNAii100310846.
PROiA6NGH8.

Gene expression databases

BgeeiENSG00000157999.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiANR61_HUMAN
AccessioniPrimary (citable) accession number: A6NGH8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 22, 2008
Last modified: November 2, 2016
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.