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A6NGG3 (CI092_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative uncharacterized protein C9orf92
Gene names
Name:C9orf92
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length77 AA.
Sequence statusComplete.
Protein existencePredicted

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: A6NGG3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: A6NGG3-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MELNTNIKSKKGLGRRNLKPMNGAWPPARREM
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7777Putative uncharacterized protein C9orf92
PRO_0000316783

Natural variations

Alternative sequence11M → MELNTNIKSKKGLGRRNLKP MNGAWPPARREM in isoform 2.
VSP_030775

Experimental info

Sequence conflict271Q → R in BG220529. Ref.1
Sequence conflict721S → P in BG220529. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 215CD74E88B64771

FASTA778,520
        10         20         30         40         50         60 
MARFQRTKER EEDRCSLNIY YVRNTTQGTA PACVGKRMQP SPTGKGGKCC TVHGLTRKIH 

        70 
NVQPNLQSPI LSAACVD 

« Hide

Isoform 2 [UniParc].

Checksum: C6E476F84EA79DA1
Show »

FASTA10812,066

References

[1]"Creation of genome-wide protein expression libraries using random activation of gene expression."
Harrington J.J., Sherf B., Rundlett S., Jackson P.D., Perry R., Cain S., Leventhal C., Thornton M., Ramachandran R., Whittington J., Lerner L., Costanzo D., McElligott K., Boozer S., Mays R., Smith E., Veloso N., Klika A. expand/collapse author list , Hess J., Cothren K., Lo K., Offenbacher J., Danzig J., Ducar M.
Nat. Biotechnol. 19:440-445(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[2]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BG220529 mRNA. No translation available.
AL513424 Genomic DNA. No translation available.
CCDSCCDS65012.1. [A6NGG3-2]
RefSeqNP_001258758.1. NM_001271829.1. [A6NGG3-2]
UniGeneHs.586441.

3D structure databases

ProteinModelPortalA6NGG3.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA6NGG3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000380683; ENSP00000370058; ENSG00000205549. [A6NGG3-2]
ENST00000380685; ENSP00000370060; ENSG00000205549. [A6NGG3-1]
GeneID100129385.
KEGGhsa:100129385.
UCSCuc031tcu.1. human. [A6NGG3-2]
uc031tcv.1. human. [A6NGG3-1]

Organism-specific databases

CTD100129385.
GeneCardsGC09M016194.
HGNCHGNC:19054. C9orf92.
neXtProtNX_A6NGG3.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG113482.
HOGENOMHOG000111651.
InParanoidA6NGG3.
OMAMELNTNI.
OrthoDBEOG73806S.
TreeFamTF354093.

Gene expression databases

BgeeA6NGG3.
GenevestigatorA6NGG3.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameCI092_HUMAN
AccessionPrimary (citable) accession number: A6NGG3
Secondary accession number(s): A6NMF8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 24, 2007
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM