A6NGG3 (CI092_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein C9orf92

Gene names

Name:

C9orf92

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	77 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: A6NGG3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: A6NGG3-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MELNTNIKSKKGLGRRNLKPMNGAWPPARREM

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 77	77	Putative uncharacterized protein C9orf92		PRO_0000316783
Natural variations
	Alternative sequence	1	1	M → MELNTNIKSKKGLGRRNLKP MNGAWPPARREM in isoform 2.		VSP_030775
Experimental info
	Sequence conflict	27	1	Q → R in BG220529. Ref.1
	Sequence conflict	72	1	S → P in BG220529. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 215CD74E88B64771	FASTA	77	8,520
	10 20 30 40 50 60 MARFQRTKER EEDRCSLNIY YVRNTTQGTA PACVGKRMQP SPTGKGGKCC TVHGLTRKIH 70 NVQPNLQSPI LSAACVD
	Isoform 2 [UniParc]. Checksum: C6E476F84EA79DA1	FASTA	108	12,066
	10 20 30 40 50 60 MELNTNIKSK KGLGRRNLKP MNGAWPPARR EMARFQRTKE REEDRCSLNI YYVRNTTQGT 70 80 90 100 APACVGKRMQ PSPTGKGGKC CTVHGLTRKI HNVQPNLQSP ILSAACVD

References

[1]

"Creation of genome-wide protein expression libraries using random activation of gene expression." Harrington J.J., Sherf B., Rundlett S., Jackson P.D., Perry R., Cain S., Leventhal C., Thornton M., Ramachandran R., Whittington J., Lerner L., Costanzo D., McElligott K., Boozer S., Mays R., Smith E., Veloso N., Klika A. , Hess J., Cothren K., Lo K., Offenbacher J., Danzig J., Ducar M. Nat. Biotechnol. 19:440-445(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).

[2]

"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BG220529 mRNA. No translation available. AL513424 Genomic DNA. No translation available.
IPI	IPI00644083. IPI00647376.
RefSeq	NP_001258758.1. NM_001271829.1.
UniGene	Hs.586441.
3D structure databases
ProteinModelPortal	A6NGG3.
ModBase	Search...
Proteomic databases
PRIDE	A6NGG3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000357468; ENSP00000350060; ENSG00000205549. ENST00000380683; ENSP00000370058; ENSG00000205549. ENST00000380685; ENSP00000370060; ENSG00000205549.
GeneID	100129385.
KEGG	hsa:100129385.
Organism-specific databases
CTD	100129385.
GeneCards	GC09M016194.
HGNC	HGNC:19054. C9orf92.
neXtProt	NX_A6NGG3.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG113482.
HOGENOM	HOG000111651.
InParanoid	A6NGG3.
OMA	SKKGVGR.
OrthoDB	EOG4PG62C.
Gene expression databases
Bgee	A6NGG3.
Genevestigator	A6NGG3.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CI092_HUMAN

Accession

Primary (citable) accession number: A6NGG3
Secondary accession number(s): A6NMF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	July 24, 2007
Last modified:	May 29, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.