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Protein

Putative zinc finger and SCAN domain-containing protein 5C

Gene

ZSCAN5C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

May be involved in transcriptional regulation.By similarity

Caution

Could be the product of a pseudogene.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri356 – 378C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 434C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri440 – 462C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri468 – 490C2H2-type 5PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative zinc finger and SCAN domain-containing protein 5CCurated
Alternative name(s):
Zinc finger and SCAN domain-containing protein 5C pseudogeneImported
Gene namesi
Name:ZSCAN5CImported
Synonyms:ZSCAN5CPImported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000204532.6
HGNCiHGNC:34294 ZSCAN5C
neXtProtiNX_A6NGD5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204532
PharmGKBiPA162411044

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003321701 – 496Putative zinc finger and SCAN domain-containing protein 5CAdd BLAST496

Proteomic databases

PaxDbiA6NGD5
PRIDEiA6NGD5

PTM databases

iPTMnetiA6NGD5
PhosphoSitePlusiA6NGD5

Expressioni

Gene expression databases

BgeeiENSG00000204532

Organism-specific databases

HPAiHPA041263
HPA043123
HPA046836
HPA060667

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000365443

Structurei

3D structure databases

ProteinModelPortaliA6NGD5
SMRiA6NGD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 126SCAN boxPROSITE-ProRule annotationAdd BLAST83

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri356 – 378C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 434C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri440 – 462C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri468 – 490C2H2-type 5PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00710000106788
HOGENOMiHOG000060216
HOVERGENiHBG072183
InParanoidiA6NGD5
OMAiKVFTYKA
OrthoDBiEOG091G0B1S
PhylomeDBiA6NGD5
TreeFamiTF341155

Family and domain databases

CDDicd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF02023 SCAN, 1 hit
SMARTiView protein in SMART
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequencei

Sequence statusi: Complete.

A6NGD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAANCTSSWS LGESCNSPGS EPPQSMPSPA TQLGNHDSDP ETCHVNFRMF
60 70 80 90 100
SCPKESDPIQ ALRKLTELCH LWLRPDLHTK EQILDMLVME QFMISMPQEL
110 120 130 140 150
QVLVMMNGVQ SCKDLEDLLR NNRRPKKWSV VSFLGKEYLM QESDVEMAEA
160 170 180 190 200
PASVRDDPRH VSSQRTSSVN QMCPEEGQAS QELQTLPRVP ALFRRQEEDF
210 220 230 240 250
LLPETTVMKG DPKALRPKPT LEKDLEEDRE ENPGLTSPEP QLPNSPTGVV
260 270 280 290 300
GAKEGKEPQK RASVENVDAD TPSACVVERE ASTHSGSRGD ALNLRGLKRS
310 320 330 340 350
KPDATSISQE EPQGEATPVG NRESPGQAEI NPVHSPGPAG PVSHPSGQEV
360 370 380 390 400
KELLPFACEV CGKRFKYRGK LAVHTRSHTG ERLFQCNLCG KRFMQRIGLQ
410 420 430 440 450
FHQRTHTGER PYTCDICQKQ FTQKSYLKCH KRSHTGEKPF ECKDCKKVFT
460 470 480 490
YKANLKEHQR IHSGEKPHKC SKCPRAFGRP ATLRRHQKTH REATSQ
Length:496
Mass (Da):55,729
Last modified:July 24, 2007 - v1
Checksum:iE677765AEDE42466
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05292724Q → R. Corresponds to variant dbSNP:rs10419548Ensembl.1
Natural variantiVAR_042970181Q → R. Corresponds to variant dbSNP:rs4801690Ensembl.1
Natural variantiVAR_042971197E → D. Corresponds to variant dbSNP:rs12979551Ensembl.1
Natural variantiVAR_052928259Q → K. Corresponds to variant dbSNP:rs1865102Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011506 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000376267; ENSP00000365443; ENSG00000204532
ENST00000534327; ENSP00000435234; ENSG00000204532
UCSCiuc061dec.1 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiZSA5C_HUMAN
AccessioniPrimary (citable) accession number: A6NGD5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 24, 2007
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health