Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transmembrane protein 221

Gene

TMEM221

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 221
Gene namesi
Name:TMEM221
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000188051.6
HGNCiHGNC:21943 TMEM221
neXtProtiNX_A6NGB7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei125 – 145HelicalSequence analysisAdd BLAST21
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiTMEM221

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003321341 – 291Transmembrane protein 221Add BLAST291

Proteomic databases

PaxDbiA6NGB7
PRIDEiA6NGB7

Expressioni

Gene expression databases

BgeeiENSG00000188051
CleanExiHS_TMEM221
GenevisibleiA6NGB7 HS

Organism-specific databases

HPAiHPA041580

Structurei

3D structure databases

ProteinModelPortaliA6NGB7
SMRiA6NGB7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IXCQ Eukaryota
ENOG4111KH9 LUCA
GeneTreeiENSGT00390000001907
HOGENOMiHOG000202499
HOVERGENiHBG108583
InParanoidiA6NGB7
OMAiMARSYGG
OrthoDBiEOG091G0P72
PhylomeDBiA6NGB7
TreeFamiTF336085

Family and domain databases

InterProiView protein in InterPro
IPR029201 Jiraiya
PfamiView protein in Pfam
PF15038 Jiraiya, 1 hit

Sequencei

Sequence statusi: Complete.

A6NGB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARSYGGRVL AAMTLLGIAA AVLAALGAQL LFQLQAGRAE LRGLRAEGLG
60 70 80 90 100
QELGAGPGLP EDAAGTLLPL AAALAALVLV LGFTCLLLAA LCGHLGAELA
110 120 130 140 150
RGPGPRRSDW FLYDCRLLRH VALGLFCCGI SVYLAALSIY ALLLFEIETG
160 170 180 190 200
AAAASILGSG TLVLVAVLTH TLLRAARAAR RGLHELSPPS FEDDLARPAE
210 220 230 240 250
VSKASPRAQP QQGIHRRTPY STCPEPGDPF GSMATATAPA ALEGGWESSL
260 270 280 290
PASRMHRTLS AGLGHWDGVT HEMRRMLGHR PGSMGKDSTL V
Length:291
Mass (Da):30,293
Last modified:October 31, 2012 - v3
Checksum:i99DAFE4307961118
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010319 Genomic DNA No translation available.
CCDSiCCDS54230.1
RefSeqiNP_001177773.1, NM_001190844.1
UniGeneiHs.436603

Genome annotation databases

EnsembliENST00000341130; ENSP00000342162; ENSG00000188051
GeneIDi100130519
KEGGihsa:100130519
UCSCiuc021uqh.1 human

Similar proteinsi

Entry informationi

Entry nameiTM221_HUMAN
AccessioniPrimary (citable) accession number: A6NGB7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: October 31, 2012
Last modified: September 27, 2017
This is version 68 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health