A6NGA9 (TM202_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transmembrane protein 202

Gene names

Name:

TMEM202

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	273 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Polymorphism
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 273	273	Transmembrane protein 202		PRO_0000317201
Regions
	Transmembrane	53 – 75	23	Helical; Potential
	Transmembrane	121 – 141	21	Helical; Potential
	Transmembrane	155 – 175	21	Helical; Potential
	Transmembrane	189 – 209	21	Helical; Potential
Natural variations
	Natural variant	204	1	M → L. Corresponds to variant rs16956904 [ dbSNP | Ensembl ].		VAR_051434

Sequences

	Sequence		Length	Mass (Da)
	A6NGA9 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 7912F1A665B28424	FASTA	273	31,353
	10 20 30 40 50 60 MERREHLTLT FHSPEVPKIK GNRKYQRPTV PAKKHPSASM SCQRQQQLMD QAHIYIRTLC 70 80 90 100 110 120 GSLCSFSLLM LIAMSPLNWV QFLVIKNGLE LYAGLWTLCN HELCWSHTPK PPYYLQYSRA 130 140 150 160 170 180 FFLISVFTIL TGLGWLFSSW ILNRGSMTTN LDLKVSMLSF ISATCLLLCL NLFVAQVHWH 190 200 210 220 230 240 TRDAMESDLL WTYYLNWCSD IFYMFAGIIS LLNYLTSRSP ACDENVTVIP TERSRLGVGP 250 260 270 VTTVSPAKDE GPRSEMESLS VREKNLPKSG LWW

References

[1]

"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC079322 Genomic DNA. No translation available.
IPI	IPI00250368.
RefSeq	NP_001073931.1. NM_001080462.1.
UniGene	Hs.446069.
3D structure databases
ProteinModelPortal	A6NGA9.
ModBase	Search...
PTM databases
PhosphoSite	A6NGA9.
Proteomic databases
PaxDb	A6NGA9.
PRIDE	A6NGA9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000341689; ENSP00000340212; ENSG00000187806.
GeneID	338949.
KEGG	hsa:338949.
UCSC	uc002auq.3. human.
Organism-specific databases
CTD	338949.
GeneCards	GC15P072690.
HGNC	HGNC:33733. TMEM202.
HPA	HPA049035.
neXtProt	NX_A6NGA9.
PharmGKB	PA162406376.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG40198.
HOGENOM	HOG000090211.
HOVERGEN	HBG094967.
InParanoid	A6NGA9.
OMA	WSHTPKP.
OrthoDB	EOG49CQ87.
PhylomeDB	A6NGA9.
Gene expression databases
ArrayExpress	A6NGA9.
Bgee	A6NGA9.
CleanEx	HS_TMEM202.
Genevestigator	A6NGA9.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	338949.
NextBio	97199.

Entry information

Entry name

TM202_HUMAN

Accession

Primary (citable) accession number: A6NGA9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	July 24, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.