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A6NGA9

- TM202_HUMAN

UniProt

A6NGA9 - TM202_HUMAN

Protein

Transmembrane protein 202

Gene

TMEM202

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (24 Jul 2007)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transmembrane protein 202
    Gene namesi
    Name:TMEM202
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:33733. TMEM202.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162406376.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Transmembrane protein 202PRO_0000317201Add
    BLAST

    Proteomic databases

    PaxDbiA6NGA9.
    PRIDEiA6NGA9.

    PTM databases

    PhosphoSiteiA6NGA9.

    Expressioni

    Gene expression databases

    BgeeiA6NGA9.
    CleanExiHS_TMEM202.
    GenevestigatoriA6NGA9.

    Organism-specific databases

    HPAiHPA049035.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NGA9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei53 – 7523HelicalSequence AnalysisAdd
    BLAST
    Transmembranei121 – 14121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei155 – 17521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei189 – 20921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG40198.
    HOGENOMiHOG000090211.
    HOVERGENiHBG094967.
    InParanoidiA6NGA9.
    OMAiWSHTPKP.
    OrthoDBiEOG74N5HH.
    PhylomeDBiA6NGA9.
    TreeFamiTF337324.

    Sequencei

    Sequence statusi: Complete.

    A6NGA9-1 [UniParc]FASTAAdd to Basket

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    MERREHLTLT FHSPEVPKIK GNRKYQRPTV PAKKHPSASM SCQRQQQLMD    50
    QAHIYIRTLC GSLCSFSLLM LIAMSPLNWV QFLVIKNGLE LYAGLWTLCN 100
    HELCWSHTPK PPYYLQYSRA FFLISVFTIL TGLGWLFSSW ILNRGSMTTN 150
    LDLKVSMLSF ISATCLLLCL NLFVAQVHWH TRDAMESDLL WTYYLNWCSD 200
    IFYMFAGIIS LLNYLTSRSP ACDENVTVIP TERSRLGVGP VTTVSPAKDE 250
    GPRSEMESLS VREKNLPKSG LWW 273
    Length:273
    Mass (Da):31,353
    Last modified:July 24, 2007 - v1
    Checksum:i7912F1A665B28424
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti204 – 2041M → L.
    Corresponds to variant rs16956904 [ dbSNP | Ensembl ].
    VAR_051434

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC079322 Genomic DNA. No translation available.
    CCDSiCCDS32287.1.
    RefSeqiNP_001073931.1. NM_001080462.1.
    UniGeneiHs.446069.

    Genome annotation databases

    EnsembliENST00000341689; ENSP00000340212; ENSG00000187806.
    GeneIDi338949.
    KEGGihsa:338949.
    UCSCiuc002auq.3. human.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC079322 Genomic DNA. No translation available.
    CCDSi CCDS32287.1.
    RefSeqi NP_001073931.1. NM_001080462.1.
    UniGenei Hs.446069.

    3D structure databases

    ProteinModelPortali A6NGA9.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei A6NGA9.

    Proteomic databases

    PaxDbi A6NGA9.
    PRIDEi A6NGA9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000341689 ; ENSP00000340212 ; ENSG00000187806 .
    GeneIDi 338949.
    KEGGi hsa:338949.
    UCSCi uc002auq.3. human.

    Organism-specific databases

    CTDi 338949.
    GeneCardsi GC15P072690.
    HGNCi HGNC:33733. TMEM202.
    HPAi HPA049035.
    neXtProti NX_A6NGA9.
    PharmGKBi PA162406376.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG40198.
    HOGENOMi HOG000090211.
    HOVERGENi HBG094967.
    InParanoidi A6NGA9.
    OMAi WSHTPKP.
    OrthoDBi EOG74N5HH.
    PhylomeDBi A6NGA9.
    TreeFami TF337324.

    Miscellaneous databases

    GenomeRNAii 338949.
    NextBioi 97199.
    PROi A6NGA9.

    Gene expression databases

    Bgeei A6NGA9.
    CleanExi HS_TMEM202.
    Genevestigatori A6NGA9.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
      Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
      , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
      Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiTM202_HUMAN
    AccessioniPrimary (citable) accession number: A6NGA9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3