A6NFN2 (A6NFN2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Abl interactor 1 Ensembl ENSP00000347555

Gene names

Name:

ABI1 Ensembl ENSP00000347555

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000347555

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	509 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 SH3 domain. RuleBase RU003338
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000347555

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338 SAAS SAAS000108
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6NFN2 [UniParc]. Last modified January 15, 2008. Version 2. Checksum: C835E45FBF66BC9B	FASTA	509	55,260
	10 20 30 40 50 60 MAELQMLLEE EIPSGKRALI ESYQNLTRVA DYCENNYIQA TDKRKALEET KAYTTQSLAS 70 80 90 100 110 120 VAYQINALAN NVLQLLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR 130 140 150 160 170 180 THKIIAPANM ERPVRYIRKP IDYTVLDDVG HGVKKWHKII HGNNQPARTG TLSRTNPPTQ 190 200 210 220 230 240 KPPSPPMSGR GTLGRNTPYK TLEPVKPPTV PNDYMTSPAR LGSQHSPGRT ASLNQRPRTH 250 260 270 280 290 300 SGSSGGSGSR ENSGSSSIGI PIAVPTPSPP TIGPENISVP PPSGAPPAPP LAPLLPVSTV 310 320 330 340 350 360 IAAPGSAPGS QYGTMTRQIS RHNSTTSSTS SGGYRRTPSV TAQFSAQPHV NGGPLYSQNS 370 380 390 400 410 420 ISIAPPPPPM PQLTPQIPLT GFVARVQENI ADSPTPPPPP PPDDIPMFDD SPPPPPPPPV 430 440 450 460 470 480 DYEDEEAAVV QYNDPYADGD PAWAPKNYIE KVVAIYDYTK DKDDELSFME GAIIYVIKKN 490 500 DDGWYEGVCN RVTGLFPGNY VESIMHYTD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL139404 Genomic DNA. No translation available. AL390961 Genomic DNA. No translation available.
IPI	IPI00480028.
3D structure databases
ProteinModelPortal	A6NFN2.
SMR	A6NFN2. Positions 1-154, 437-504.
ModBase	Search...
Protein-protein interaction databases
STRING	A6NFN2.
Proteomic databases
PRIDE	A6NFN2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000355394; ENSP00000347555; ENSG00000136754.
Organism-specific databases
HGNC	HGNC:11320. ABI1.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000293213.
HOVERGEN	HBG050446.
OMA	VGHGVKE.
OrthoDB	EOG4PZJ6Q.
Gene expression databases
ArrayExpress	A6NFN2.
Bgee	A6NFN2.
Family and domain databases
InterPro	IPR012849. Abl-interactor_HHR_dom. IPR000108. p67phox. IPR001452. SH3_domain. IPR000727. T_SNARE_dom. [Graphical view]
Pfam	PF07815. Abi_HHR. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX. PR00452. SH3DOMAIN.
SMART	SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF50044. SH3. 1 hit.
PROSITE	PS50002. SH3. 1 hit. PS50192. T_SNARE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ABI1. human.
NextBio	35462525.

Entry information

Entry name

A6NFN2_HUMAN

Accession

Primary (citable) accession number: A6NFN2

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	January 15, 2008
Last modified:	April 3, 2013
This is version 38 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.