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A6NFN2 (A6NFN2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length509 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000347555

Ontologies

Keywords
   DomainSH3 domain RuleBase RU003338
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functionprotein tyrosine kinase activator activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A6NFN2 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: C835E45FBF66BC9B

FASTA50955,260
        10         20         30         40         50         60 
MAELQMLLEE EIPSGKRALI ESYQNLTRVA DYCENNYIQA TDKRKALEET KAYTTQSLAS 

        70         80         90        100        110        120 
VAYQINALAN NVLQLLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR 

       130        140        150        160        170        180 
THKIIAPANM ERPVRYIRKP IDYTVLDDVG HGVKKWHKII HGNNQPARTG TLSRTNPPTQ 

       190        200        210        220        230        240 
KPPSPPMSGR GTLGRNTPYK TLEPVKPPTV PNDYMTSPAR LGSQHSPGRT ASLNQRPRTH 

       250        260        270        280        290        300 
SGSSGGSGSR ENSGSSSIGI PIAVPTPSPP TIGPENISVP PPSGAPPAPP LAPLLPVSTV 

       310        320        330        340        350        360 
IAAPGSAPGS QYGTMTRQIS RHNSTTSSTS SGGYRRTPSV TAQFSAQPHV NGGPLYSQNS 

       370        380        390        400        410        420 
ISIAPPPPPM PQLTPQIPLT GFVARVQENI ADSPTPPPPP PPDDIPMFDD SPPPPPPPPV 

       430        440        450        460        470        480 
DYEDEEAAVV QYNDPYADGD PAWAPKNYIE KVVAIYDYTK DKDDELSFME GAIIYVIKKN 

       490        500 
DDGWYEGVCN RVTGLFPGNY VESIMHYTD 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL139404 Genomic DNA. No translation available.
AL390961 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalA6NFN2.
SMRA6NFN2. Positions 1-154, 437-504.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA6NFN2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000355394; ENSP00000347555; ENSG00000136754.

Organism-specific databases

HGNCHGNC:11320. ABI1.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000293213.
HOVERGENHBG050446.
OMAVGHGVKE.

Gene expression databases

ArrayExpressA6NFN2.
BgeeA6NFN2.

Family and domain databases

InterProIPR028457. ABI.
IPR028456. ABI1.
IPR012849. Abl-interactor_HHR_dom.
IPR001452. SH3_domain.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERPTHR10460. PTHR10460. 1 hit.
PTHR10460:SF2. PTHR10460:SF2. 1 hit.
PfamPF07815. Abi_HHR. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SSF50044. 1 hit.
PROSITEPS50002. SH3. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSABI1. human.
NextBio35462525.

Entry information

Entry nameA6NFN2_HUMAN
AccessionPrimary (citable) accession number: A6NFN2
Entry history
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: January 15, 2008
Last modified: April 16, 2014
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.