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Protein

Putative olfactory receptor 2W5

Gene

OR2W5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Odorant receptor.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processOlfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiR-HSA-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative olfactory receptor 2W5
Gene namesi
Name:OR2W5
Synonyms:OR2W5P
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:15424. OR2W5.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 50Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei58 – 78Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei98 – 118Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei140 – 160Helical; Name=4Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32218.

Polymorphism and mutation databases

BioMutaiOR2W5.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003454181 – 320Putative olfactory receptor 2W5Add BLAST320

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi5N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 179PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiA6NFC9.

PTM databases

iPTMnetiA6NFC9.
PhosphoSitePlusiA6NFC9.

Expressioni

Gene expression databases

CleanExiHS_OR2W5.

Structurei

3D structure databases

ProteinModelPortaliA6NFC9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiA6NFC9.
PhylomeDBiA6NFC9.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NFC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKDNASYLQ AFILVGSSDR PGLEKILFAV ILIFCILTLV GNTAIILLLV
60 70 80 90 100
MDVRLHTPMY FFLGNLSFLD LCFTASIAPQ LLWNLGGPEK TITYHGCVAQ
110 120 130 140 150
LYIYMMLGST ECVLLVVMSH DRYVAVCRSL HYMAVMRPHL CLQLVTVAWC
160 170 180 190 200
CGFLNSFIMC PQTMQLSRCG RRRVDHFLCE MPALIAMSCE ETMLVEAIHL
210 220 230 240 250
CPGGGSPPGA ALPHPHLLWR DCSRGAEDEV SSRAKESLPH LLFSPHSGLS
260 270 280 290 300
LLRNHHLRVP EAGQQLLPRS GEVPDSLLHH RHSQHQPPHL HFEEQGCEGD
310 320
HEETSGVGER GWGASTRGTL
Length:320
Mass (Da):35,528
Last modified:July 24, 2007 - v1
Checksum:iBB7F97B2C06564D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606804 Genomic DNA. No translation available.
BC137203 mRNA. Translation: AAI37204.1.
BC137204 mRNA. Translation: AAI37205.1.
RefSeqiNP_001004698.1. NM_001004698.2.
UniGeneiHs.591526.

Genome annotation databases

GeneIDi441932.
KEGGihsa:441932.

Similar proteinsi

Entry informationi

Entry nameiOR2W5_HUMAN
AccessioniPrimary (citable) accession number: A6NFC9
Secondary accession number(s): B9EH85
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 24, 2007
Last modified: August 30, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. SIMILARITY comments
    Index of protein domains and families