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Protein

Putative nuclear envelope pore membrane protein POM 121B

Gene

POM121B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Putative component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

mRNA transport, Protein transport, Translocation, Transport

Protein family/group databases

TCDBi1.I.1.1.3. the nuclear pore complex (npc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative nuclear envelope pore membrane protein POM 121B
Gene namesi
Name:POM121B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:34004. POM121B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nuclear pore complex, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 834834Putative nuclear envelope pore membrane protein POM 121BPRO_0000346774Add
BLAST

Proteomic databases

EPDiA6NF01.
MaxQBiA6NF01.
PaxDbiA6NF01.
PeptideAtlasiA6NF01.
PRIDEiA6NF01.

Expressioni

Organism-specific databases

HPAiHPA043809.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000414208.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi346 – 531186Thr-richAdd
BLAST

Domaini

Contains F-X-F-G repeats.By similarity

Sequence similaritiesi

Belongs to the POM121 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IM0V. Eukaryota.
ENOG4112BJY. LUCA.
HOVERGENiHBG053628.
InParanoidiA6NF01.

Family and domain databases

InterProiIPR026090. POM121.
[Graphical view]
PANTHERiPTHR23193:SF5. PTHR23193:SF5. 2 hits.

Sequencei

Sequence statusi: Complete.

A6NF01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRVRTSEL WKRNGPSSSP FSSPASSRSQ TPERPAKKIR EEEMCHHSSS
60 70 80 90 100
STPLAADKES QGEKAADTTP RKKQNSNSQS TPGSSGQRKR KVQLLPSRRG
110 120 130 140 150
EQLTLPPPPQ LGYSITAEDL DLEKKASLQW FNQALEDKSD AASNSVTETP
160 170 180 190 200
PITQPSFTFT LPAAAPASPP TSLLAPSTNP LLESLKKMQT PPSLPPCPES
210 220 230 240 250
AGAATTEALS PPKTPNLLPP LGLSQSGPPG LLPSPSFDSN PPTTLLGLIP
260 270 280 290 300
APSMVPATDT KAPPTLQAET TTKPQATSAP SPAPKQSFLF GTQNTSPSSP
310 320 330 340 350
AAPAASSASP MFKPIFTAPP KSEKEGPTPP GPSVSATAPS SSSLPTTTST
360 370 380 390 400
TAPTFQPVFS SMGPPASVPL PAPFFKQTTT PATAPTTTAP LFTGLASATS
410 420 430 440 450
AVAPITSASP STDSASKPAF GFGINSVSSS SVSTTTSTAT AASQPFLFGA
460 470 480 490 500
PQASAASFTP AMGSIFQFGK PPALPTTTTV TTFSQSLPTA VPTATSSSAA
510 520 530 540 550
DFSGFGSTLA TSAPATSSQP TLTFSNTSTP TFNIPFGSSA KSPLPSYPGA
560 570 580 590 600
NPQPAFGAAE GQPPGAAKPA LTPSFGSSFT FGNSAAPAAA PTPAPPSMIK
610 620 630 640 650
IVPAHVPTPI QPTFGGATHS AFGLKATASA FGAPASSQPA FGGSTAVFSF
660 670 680 690 700
GAATSSGFGA TTQTASSGSS SSVFGSTTPS PFTFGGSAAP AGSGSFGINV
710 720 730 740 750
ATPGSSATTG AFSFGAGQSG STATSTPFAG GLGQNALGTT GQSTPFAFNV
760 770 780 790 800
GSTTESKPVF GGTATPTFGL NTPAPGVGTS GSSLSFGASS APAQGFVGVA
810 820 830
PFGSAAPSFS IGAGSKTLGA RQRLQARRQH TRKK
Length:834
Mass (Da):83,015
Last modified:September 2, 2008 - v2
Checksum:i3063DC34DD83F5B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073841 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073841 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000414208.

Protein family/group databases

TCDBi1.I.1.1.3. the nuclear pore complex (npc) family.

Proteomic databases

EPDiA6NF01.
MaxQBiA6NF01.
PaxDbiA6NF01.
PeptideAtlasiA6NF01.
PRIDEiA6NF01.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiPOM121B.
HGNCiHGNC:34004. POM121B.
HPAiHPA043809.
neXtProtiNX_A6NF01.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IM0V. Eukaryota.
ENOG4112BJY. LUCA.
HOVERGENiHBG053628.
InParanoidiA6NF01.

Family and domain databases

InterProiIPR026090. POM121.
[Graphical view]
PANTHERiPTHR23193:SF5. PTHR23193:SF5. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiP121B_HUMAN
AccessioniPrimary (citable) accession number: A6NF01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 6, 2016
This is version 56 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.