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Protein
Submitted name:

Calbindin 2, 29kDa (Calretinin), isoform CRA_b

Gene

CALB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Calbindin 2, 29kDa (Calretinin), isoform CRA_bImported
Submitted name:
CalretininImported
Gene namesi
Name:CALB2Imported
ORF Names:hCG_2011413Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:1435. CALB2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172137.
ENSG00000282830.
PharmGKBiPA26027.

PTM / Processingi

Proteomic databases

MaxQBiA6NER6.
PeptideAtlasiA6NER6.
PRIDEiA6NER6.

Expressioni

Gene expression databases

BgeeiENSG00000172137.
ExpressionAtlasiA6NER6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000307508.

Structurei

3D structure databases

ProteinModelPortaliA6NER6.
SMRiA6NER6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 51EF-handInterPro annotationAdd BLAST36
Domaini63 – 98EF-handInterPro annotationAdd BLAST36
Domaini107 – 142EF-handInterPro annotationAdd BLAST36
Domaini151 – 186EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG0027. Eukaryota.
COG5126. LUCA.
GeneTreeiENSGT00390000013118.
HOGENOMiHOG000231866.
HOVERGENiHBG000855.

Family and domain databases

CDDicd00051. EFh. 2 hits.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR029646. CALB2.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PANTHERiPTHR19972:SF4. PTHR19972:SF4. 1 hit.
PfamiPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTiSM00054. EFh. 4 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NER6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK
60 70 80 90 100
ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL
110 120 130 140 150
CFRQHVGSSA EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP
160 170 180 190
KLQEYTQTIL RMFDLNGDGK LGLSEMSRIE AATLTSMSWM PF
Length:192
Mass (Da):22,155
Last modified:July 24, 2007 - v1
Checksum:i7A69EA37E7D3D246
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009136 Genomic DNA. No translation available.
AC106736 Genomic DNA. No translation available.
KF456204 Genomic DNA. No translation available.
CH471166 Genomic DNA. Translation: EAW59241.1.
RefSeqiNP_009019.1. NM_007088.3.
UniGeneiHs.106857.

Genome annotation databases

EnsembliENST00000349553; ENSP00000340294; ENSG00000172137.
ENST00000635154; ENSP00000489007; ENSG00000282830.
GeneIDi794.
UCSCiuc002fac.6. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009136 Genomic DNA. No translation available.
AC106736 Genomic DNA. No translation available.
KF456204 Genomic DNA. No translation available.
CH471166 Genomic DNA. Translation: EAW59241.1.
RefSeqiNP_009019.1. NM_007088.3.
UniGeneiHs.106857.

3D structure databases

ProteinModelPortaliA6NER6.
SMRiA6NER6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000307508.

Proteomic databases

MaxQBiA6NER6.
PeptideAtlasiA6NER6.
PRIDEiA6NER6.

Protocols and materials databases

DNASUi794.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000349553; ENSP00000340294; ENSG00000172137.
ENST00000635154; ENSP00000489007; ENSG00000282830.
GeneIDi794.
UCSCiuc002fac.6. human.

Organism-specific databases

CTDi794.
HGNCiHGNC:1435. CALB2.
OpenTargetsiENSG00000172137.
ENSG00000282830.
PharmGKBiPA26027.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0027. Eukaryota.
COG5126. LUCA.
GeneTreeiENSGT00390000013118.
HOGENOMiHOG000231866.
HOVERGENiHBG000855.

Miscellaneous databases

GenomeRNAii794.

Gene expression databases

BgeeiENSG00000172137.
ExpressionAtlasiA6NER6. baseline and differential.

Family and domain databases

CDDicd00051. EFh. 2 hits.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR029646. CALB2.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PANTHERiPTHR19972:SF4. PTHR19972:SF4. 1 hit.
PfamiPF13499. EF-hand_7. 2 hits.
[Graphical view]
SMARTiSM00054. EFh. 4 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA6NER6_HUMAN
AccessioniPrimary (citable) accession number: A6NER6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: November 30, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.