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Protein
Submitted name:

Calbindin 2, 29kDa (Calretinin), isoform CRA_b

Gene

CALB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi29 – 40PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi76 – 87PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi120 – 131PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi164 – 175PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Calbindin 2, 29kDa (Calretinin), isoform CRA_bImported
Submitted name:
CalretininImported
Gene namesi
Name:CALB2Imported
ORF Names:hCG_2011413Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000172137.18.
HGNCiHGNC:1435. CALB2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172137.
PharmGKBiPA26027.

PTM / Processingi

Proteomic databases

MaxQBiA6NER6.

Expressioni

Gene expression databases

BgeeiENSG00000172137.
ExpressionAtlasiA6NER6. baseline and differential.

Structurei

3D structure databases

SMRiA6NER6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 51EF-handInterPro annotationAdd BLAST36
Domaini63 – 98EF-handInterPro annotationAdd BLAST36
Domaini107 – 142EF-handInterPro annotationAdd BLAST36
Domaini151 – 186EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG0027. Eukaryota.
COG5126. LUCA.
GeneTreeiENSGT00390000013118.
HOGENOMiHOG000231866.
HOVERGENiHBG000855.

Family and domain databases

InterProiView protein in InterPro
IPR029646. CALB2.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
PANTHERiPTHR19972:SF12. PTHR19972:SF12. 1 hit.
PfamiView protein in Pfam
PF13499. EF-hand_7. 2 hits.
SMARTiView protein in SMART
SM00054. EFh. 4 hits.
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.

Sequencei

Sequence statusi: Complete.

A6NER6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK
60 70 80 90 100
ARKGSGMMSK SDNFGEKMKE FMQKYDKNSD GKIEMAELAQ ILPTEENFLL
110 120 130 140 150
CFRQHVGSSA EFMEAWRKYD TDRSGYIEAN ELKGFLSDLL KKANRPYDEP
160 170 180 190
KLQEYTQTIL RMFDLNGDGK LGLSEMSRIE AATLTSMSWM PF
Length:192
Mass (Da):22,155
Last modified:July 24, 2007 - v1
Checksum:i7A69EA37E7D3D246
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009136 Genomic DNA. No translation available.
AC106736 Genomic DNA. No translation available.
KF456204 Genomic DNA. No translation available.
CH471166 Genomic DNA. Translation: EAW59241.1.
RefSeqiNP_009019.1. NM_007088.3.
UniGeneiHs.106857.

Genome annotation databases

EnsembliENST00000349553; ENSP00000340294; ENSG00000172137.
ENST00000635154; ENSP00000489007; ENSG00000282830.
GeneIDi794.
UCSCiuc002fac.6. human.

Similar proteinsi

Entry informationi

Entry nameiA6NER6_HUMAN
AccessioniPrimary (citable) accession number: A6NER6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: September 27, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported