A6NEM1 (GG6L9_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Golgin subfamily A member 6-like protein 9

Gene names

Name:

GOLGA6L9

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the GOLGA6 family.
Sequence caution	The sequence AAH41854.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: A6NEM1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: A6NEM1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-188: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	Golgin subfamily A member 6-like protein 9		PRO_0000334675
Regions
	Coiled coil	157 – 354	198	Potential
Natural variations
	Alternative sequence	1 – 188	188	Missing in isoform 2.		VSP_033754
Experimental info
	Sequence conflict	257	1	K → E in AAH41854. Ref.2
	Sequence conflict	373	1	P → A in AAH41854. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 20, 2008. Version 3. Checksum: 16AF82DC79B78163	FASTA	432	49,096
	10 20 30 40 50 60 MWPQPRLPPH PAMSEKTQQG KLAAAKKKLK AYWQRKSPGI PAGANRKKKV NGSSPDTATS 70 80 90 100 110 120 GGYHSPGDSA TGIYGEGRAS STTLQDLESQ YQELAVALDS SSAIISQLTE NINSLVRTSK 130 140 150 160 170 180 EEKKHEIHLV QKLGRSLFKL KNQTAEPLAP QPPAGPSKVE QLQDETNHLR KELESVGRQL 190 200 210 220 230 240 QAEVENNQML SLLNRRQEER LREQEERLRE QEERLCEQEE RLCEQEERLR EQEERLCEQE 250 260 270 280 290 300 KLPGQERLLE EVEKLLKQER RQEEQERLLE RERLLDEVEE LLEQERLRQQ DERLWQQETL 310 320 330 340 350 360 RELERLRELE RMLELGWEAL YEQRAEPRSG FEELNNENKS TLQLEQQVKE LEKSGGAEEP 370 380 390 400 410 420 RGSESAAAAR PVPGAPVPQG AWMCGQAGWT PQEHPGLSGE AVGTGEAAGG AGEAACHSFR 430 AAENRELNIT II
	Isoform 2 [UniParc]. Checksum: D80A0323E3133B9F	FASTA	244	28,559
	10 20 30 40 50 60 MLSLLNRRQE ERLREQEERL REQEERLCEQ EERLCEQEER LREQEERLCE QEKLPGQERL 70 80 90 100 110 120 LEEVEKLLKQ ERRQEEQERL LERERLLDEV EELLEQERLR QQDERLWQQE TLRELERLRE 130 140 150 160 170 180 LERMLELGWE ALYEQRAEPR SGFEELNNEN KSTLQLEQQV KELEKSGGAE EPRGSESAAA 190 200 210 220 230 240 ARPVPGAPVP QGAWMCGQAG WTPQEHPGLS GEAVGTGEAA GGAGEAACHS FRAAENRELN ITII

References

[1]

"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed: 16572171] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Testis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC135995 Genomic DNA. No translation available. BC041854 mRNA. Translation: AAH41854.1. Different initiation.
IPI	IPI00719646. IPI00787094.
RefSeq	NP_937824.2. NM_198181.2.
UniGene	Hs.630181.
3D structure databases
ProteinModelPortal	A6NEM1.
ModBase	Search...
Proteomic databases
PRIDE	A6NEM1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000300515; ENSP00000300515; ENSG00000197978. ENST00000358583; ENSP00000351392; ENSG00000196648.
GeneID	440295.
KEGG	hsa:440295.
UCSC	uc002bid.2. human. uc010blt.1. human.
Organism-specific databases
CTD	440295.
GeneCards	GC15P082722.
HGNC	HGNC:37229. GOLGA6L9.
neXtProt	NX_A6NEM1.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG21649.
GeneTree	ENSGT00530000062932.
HOGENOM	HBG505666.
HOVERGEN	HBG107944.
InParanoid	A6NEM1.
OMA	WELERVL.
OrthoDB	EOG48D0WF.
Gene expression databases
Bgee	A6NEM1.
Genevestigator	A6NEM1.
Family and domain databases
ProtoNet	Search...
Other
NextBio	109115.

Entry information

Entry name

GG6L9_HUMAN

Accession

Primary (citable) accession number: A6NEM1
Secondary accession number(s): Q8IVV3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 33 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.