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A6NEH6

- TM247_HUMAN

UniProt

A6NEH6 - TM247_HUMAN

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Protein

Transmembrane protein 247

Gene

TMEM247

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 247
Gene namesi
Name:TMEM247
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:42967. TMEM247.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: Ensembl
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Transmembrane protein 247PRO_0000328813Add
BLAST

Proteomic databases

PaxDbiA6NEH6.
PRIDEiA6NEH6.

PTM databases

PhosphoSiteiA6NEH6.

Expressioni

Gene expression databases

BgeeiA6NEH6.
GenevestigatoriA6NEH6.

Organism-specific databases

HPAiHPA049130.

Structurei

3D structure databases

ProteinModelPortaliA6NEH6.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei167 – 18721HelicalSequence AnalysisAdd
BLAST
Transmembranei194 – 21421HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili121 – 15636Sequence AnalysisAdd
BLAST

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG41616.
GeneTreeiENSGT00390000002879.
HOGENOMiHOG000168313.
HOVERGENiHBG108691.
InParanoidiA6NEH6.
OMAiDPMSEGK.
OrthoDBiEOG7288SD.
PhylomeDBiA6NEH6.
TreeFamiTF337834.

Family and domain databases

InterProiIPR029200. TMEM247.
[Graphical view]
PfamiPF15444. TMEM247. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NEH6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAEDREMME ARGAGESCPT FPKMVPGDSK SEGKPRAYLE AESQKPDSSY
60 70 80 90 100
DYLEEMEACE DGGCQGPLKS LSPKSCRATK GQAGDGPKPA ELPPTPGTER
110 120 130 140 150
NPEMELEKVR MEFELTRLKY LHEKNQRQRQ HEVVMEQLQR ERQHEVVMEQ
160 170 180 190 200
LQQEAAPRLF SGGLQNFLLP QNQFAMFLYC FIFIHIIYVT KEMVFFLFAK
210
HYLFCIAAIL LCLIKTFWS
Length:219
Mass (Da):25,168
Last modified:April 8, 2008 - v2
Checksum:i83A376D61158E80E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC018682 Genomic DNA. No translation available.
CCDSiCCDS56117.1.
RefSeqiNP_001138523.1. NM_001145051.2.
UniGeneiHs.733348.

Genome annotation databases

EnsembliENST00000434431; ENSP00000388684; ENSG00000187600.
GeneIDi388946.
KEGGihsa:388946.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC018682 Genomic DNA. No translation available.
CCDSi CCDS56117.1.
RefSeqi NP_001138523.1. NM_001145051.2.
UniGenei Hs.733348.

3D structure databases

ProteinModelPortali A6NEH6.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei A6NEH6.

Proteomic databases

PaxDbi A6NEH6.
PRIDEi A6NEH6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000434431 ; ENSP00000388684 ; ENSG00000187600 .
GeneIDi 388946.
KEGGi hsa:388946.

Organism-specific databases

CTDi 388946.
GeneCardsi GC02P046657.
HGNCi HGNC:42967. TMEM247.
HPAi HPA049130.
neXtProti NX_A6NEH6.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG41616.
GeneTreei ENSGT00390000002879.
HOGENOMi HOG000168313.
HOVERGENi HBG108691.
InParanoidi A6NEH6.
OMAi DPMSEGK.
OrthoDBi EOG7288SD.
PhylomeDBi A6NEH6.
TreeFami TF337834.

Miscellaneous databases

GenomeRNAii 388946.
NextBioi 102462.
PROi A6NEH6.

Gene expression databases

Bgeei A6NEH6.
Genevestigatori A6NEH6.

Family and domain databases

InterProi IPR029200. TMEM247.
[Graphical view ]
Pfami PF15444. TMEM247. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiTM247_HUMAN
AccessioniPrimary (citable) accession number: A6NEH6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM

External Data

Dasty 3