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A6NEH6 (TM247_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transmembrane protein 247
Gene names
Name:TMEM247
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Transmembrane protein 247
PRO_0000328813

Regions

Transmembrane167 – 18721Helical; Potential
Transmembrane194 – 21421Helical; Potential
Coiled coil121 – 15636 Potential

Sequences

Sequence LengthMass (Da)Tools
A6NEH6 [UniParc].

Last modified April 8, 2008. Version 2.
Checksum: 83A376D61158E80E

FASTA21925,168
        10         20         30         40         50         60 
MAAEDREMME ARGAGESCPT FPKMVPGDSK SEGKPRAYLE AESQKPDSSY DYLEEMEACE 

        70         80         90        100        110        120 
DGGCQGPLKS LSPKSCRATK GQAGDGPKPA ELPPTPGTER NPEMELEKVR MEFELTRLKY 

       130        140        150        160        170        180 
LHEKNQRQRQ HEVVMEQLQR ERQHEVVMEQ LQQEAAPRLF SGGLQNFLLP QNQFAMFLYC 

       190        200        210 
FIFIHIIYVT KEMVFFLFAK HYLFCIAAIL LCLIKTFWS 

« Hide

References

[1]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC018682 Genomic DNA. No translation available.
RefSeqNP_001138523.1. NM_001145051.2.
UniGeneHs.733348.

3D structure databases

ProteinModelPortalA6NEH6.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteA6NEH6.

Proteomic databases

PaxDbA6NEH6.
PRIDEA6NEH6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000434431; ENSP00000388684; ENSG00000187600.
GeneID388946.
KEGGhsa:388946.

Organism-specific databases

CTD388946.
GeneCardsGC02P046657.
HGNCHGNC:42967. TMEM247.
HPAHPA049130.
neXtProtNX_A6NEH6.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG41616.
HOGENOMHOG000168313.
HOVERGENHBG108691.
InParanoidA6NEH6.
OMALFSKHYL.
OrthoDBEOG7288SD.
PhylomeDBA6NEH6.
TreeFamTF337834.

Gene expression databases

BgeeA6NEH6.
GenevestigatorA6NEH6.

Family and domain databases

ProtoNetSearch...

Other

GenomeRNAi388946.
NextBio102462.
PROA6NEH6.

Entry information

Entry nameTM247_HUMAN
AccessionPrimary (citable) accession number: A6NEH6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 2

Human chromosome 2: entries, gene names and cross-references to MIM