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A6NEH6

- TM247_HUMAN

UniProt

A6NEH6 - TM247_HUMAN

Protein

Transmembrane protein 247

Gene

TMEM247

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 2 (08 Apr 2008)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transmembrane protein 247
    Gene namesi
    Name:TMEM247
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:42967. TMEM247.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 219219Transmembrane protein 247PRO_0000328813Add
    BLAST

    Proteomic databases

    PaxDbiA6NEH6.
    PRIDEiA6NEH6.

    PTM databases

    PhosphoSiteiA6NEH6.

    Expressioni

    Gene expression databases

    BgeeiA6NEH6.
    GenevestigatoriA6NEH6.

    Organism-specific databases

    HPAiHPA049130.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NEH6.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei167 – 18721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei194 – 21421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili121 – 15636Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Coiled coil, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG41616.
    HOGENOMiHOG000168313.
    HOVERGENiHBG108691.
    InParanoidiA6NEH6.
    OMAiDPMSEGK.
    OrthoDBiEOG7288SD.
    PhylomeDBiA6NEH6.
    TreeFamiTF337834.

    Family and domain databases

    InterProiIPR029200. TMEM247.
    [Graphical view]
    PfamiPF15444. TMEM247. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6NEH6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAEDREMME ARGAGESCPT FPKMVPGDSK SEGKPRAYLE AESQKPDSSY    50
    DYLEEMEACE DGGCQGPLKS LSPKSCRATK GQAGDGPKPA ELPPTPGTER 100
    NPEMELEKVR MEFELTRLKY LHEKNQRQRQ HEVVMEQLQR ERQHEVVMEQ 150
    LQQEAAPRLF SGGLQNFLLP QNQFAMFLYC FIFIHIIYVT KEMVFFLFAK 200
    HYLFCIAAIL LCLIKTFWS 219
    Length:219
    Mass (Da):25,168
    Last modified:April 8, 2008 - v2
    Checksum:i83A376D61158E80E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC018682 Genomic DNA. No translation available.
    CCDSiCCDS56117.1.
    RefSeqiNP_001138523.1. NM_001145051.2.
    UniGeneiHs.733348.

    Genome annotation databases

    EnsembliENST00000434431; ENSP00000388684; ENSG00000187600.
    GeneIDi388946.
    KEGGihsa:388946.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC018682 Genomic DNA. No translation available.
    CCDSi CCDS56117.1.
    RefSeqi NP_001138523.1. NM_001145051.2.
    UniGenei Hs.733348.

    3D structure databases

    ProteinModelPortali A6NEH6.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei A6NEH6.

    Proteomic databases

    PaxDbi A6NEH6.
    PRIDEi A6NEH6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000434431 ; ENSP00000388684 ; ENSG00000187600 .
    GeneIDi 388946.
    KEGGi hsa:388946.

    Organism-specific databases

    CTDi 388946.
    GeneCardsi GC02P046657.
    HGNCi HGNC:42967. TMEM247.
    HPAi HPA049130.
    neXtProti NX_A6NEH6.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG41616.
    HOGENOMi HOG000168313.
    HOVERGENi HBG108691.
    InParanoidi A6NEH6.
    OMAi DPMSEGK.
    OrthoDBi EOG7288SD.
    PhylomeDBi A6NEH6.
    TreeFami TF337834.

    Miscellaneous databases

    GenomeRNAii 388946.
    NextBioi 102462.
    PROi A6NEH6.

    Gene expression databases

    Bgeei A6NEH6.
    Genevestigatori A6NEH6.

    Family and domain databases

    InterProi IPR029200. TMEM247.
    [Graphical view ]
    Pfami PF15444. TMEM247. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiTM247_HUMAN
    AccessioniPrimary (citable) accession number: A6NEH6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 51 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM

    External Data

    Dasty 3