ID   GG6L4_HUMAN             Reviewed;         574 AA.
AC   A6NEF3; D6REZ9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 3.
DT   27-MAR-2024, entry version 91.
DE   RecName: Full=Golgin subfamily A member 6-like protein 4;
GN   Name=GOLGA6L4;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- SIMILARITY: Belongs to the GOLGA6 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC136698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS73774.1; -.
DR   RefSeq; NP_001254465.2; NM_001267536.2.
DR   AlphaFoldDB; A6NEF3; -.
DR   SMR; A6NEF3; -.
DR   STRING; 9606.ENSP00000421586; -.
DR   iPTMnet; A6NEF3; -.
DR   PhosphoSitePlus; A6NEF3; -.
DR   BioMuta; GOLGA6L4; -.
DR   MassIVE; A6NEF3; -.
DR   PaxDb; 9606-ENSP00000421586; -.
DR   PeptideAtlas; A6NEF3; -.
DR   Antibodypedia; 65891; 28 antibodies from 7 providers.
DR   DNASU; 643707; -.
DR   Ensembl; ENST00000510439.7; ENSP00000421586.2; ENSG00000184206.13.
DR   GeneID; 643707; -.
DR   KEGG; hsa:643707; -.
DR   MANE-Select; ENST00000510439.7; ENSP00000421586.2; NM_001267536.3; NP_001254465.2.
DR   UCSC; uc059mrg.1; human.
DR   AGR; HGNC:27256; -.
DR   GeneCards; GOLGA6L4; -.
DR   HGNC; HGNC:27256; GOLGA6L4.
DR   HPA; ENSG00000184206; Low tissue specificity.
DR   neXtProt; NX_A6NEF3; -.
DR   VEuPathDB; HostDB:ENSG00000184206; -.
DR   eggNOG; KOG4725; Eukaryota.
DR   GeneTree; ENSGT00910000144587; -.
DR   InParanoid; A6NEF3; -.
DR   OMA; MVETERM; -.
DR   OrthoDB; 4706646at2759; -.
DR   PhylomeDB; A6NEF3; -.
DR   PathwayCommons; A6NEF3; -.
DR   BioGRID-ORCS; 643707; 52 hits in 273 CRISPR screens.
DR   GenomeRNAi; 643707; -.
DR   Pharos; A6NEF3; Tdark.
DR   PRO; PR:A6NEF3; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; A6NEF3; Protein.
DR   Bgee; ENSG00000184206; Expressed in left ovary and 98 other cell types or tissues.
DR   ExpressionAtlas; A6NEF3; baseline and differential.
DR   InterPro; IPR026737; GOLGA6L.
DR   InterPro; IPR043976; GOLGA_cons_dom.
DR   PANTHER; PTHR23143:SF19; GOLGIN SUBFAMILY A MEMBER 6-LIKE PROTEIN 10-RELATED; 1.
DR   PANTHER; PTHR23143; TRICHOHYALIN-RELATED; 1.
DR   Pfam; PF15070; GOLGA2L5; 1.
DR   Genevisible; A6NEF3; HS.
PE   3: Inferred from homology;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..574
FT                   /note="Golgin subfamily A member 6-like protein 4"
FT                   /id="PRO_0000332264"
FT   REGION          1..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          491..552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          157..496
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        50..66
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   574 AA;  67563 MW;  1B501FFBE38A1020 CRC64;
     MWPQPRFPPH PAMSEKTQQG KLAAAKKKLK AYWQRKSPGI PAGANRKKKI NGSSPDTATS
     GGYHSPGDSA TGIYGEGRAS STTLEDLESQ YQELAVALDS SSAIISQLTE NINSLVRTSK
     EEKKHEIHLV QKLGRSLFKL KNQTAEPLAP EPPAGPSKVE QLQDETNHLR KELESVGRQL
     QAEVENNQML SLLNRRQEER LREQEERLRE QEERLREQED RLHEQEERLR EQEERLCEQE
     ERLREHEERL CEQEERLCEQ EERLREQEER LHEQEERLRE QEERLCEQEE RLREQEERLC
     EQEERLREQE ERLCEQEKLP GQERLLEEVE KLLEQERRQE EQERLLERER LLEEVEKLLE
     QERQQEEQER LLERERLLEE VEKLLEQERR QEEQERLLER ERLLDEVEEL LDEVEELLEQ
     ERLRQQDERL WQQETLQELE RLRELERLRE LERMLELGWE ALYEQRAEPR SGFEELNNEN
     KSTLQLEQQV KELKKSGGAE EPRGSESAAA ARPVAGAPVP QGAWMCGQAG WTPQEHPGLS
     GEAVGTGEAA GGAGEAACHS FRAAENRELN ITII
//