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Protein
Submitted name:

Cullin-4B

Gene

CUL4B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cullin-4BImported
Gene namesi
Name:CUL4BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:2555. CUL4B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiA6NE76.
MaxQBiA6NE76.
PaxDbiA6NE76.
PRIDEiA6NE76.

Expressioni

Gene expression databases

BgeeiA6NE76.
ExpressionAtlasiA6NE76. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000384109.

Structurei

3D structure databases

ProteinModelPortaliA6NE76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 232212CullinInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2167. Eukaryota.
COG5647. LUCA.
GeneTreeiENSGT00760000119212.
HOGENOMiHOG000006909.
HOVERGENiHBG084579.

Family and domain databases

InterProiIPR033044. CUL4B.
IPR001373. Cullin_N.
IPR016159. Cullin_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11932:SF66. PTHR11932:SF66. 1 hit.
PfamiPF00888. Cullin. 1 hit.
[Graphical view]
SUPFAMiSSF74788. SSF74788. 1 hit.

Sequencei

Sequence statusi: Fragment.

A6NE76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDPDFADKP KLPENYTDET WQKLKEAVEA IQNSTSIKYN LEELYQAVEN
60 70 80 90 100
LCSYKISANL YKQLRQICED HIKAQIHQFR EDSLDSVLFL KKIDRCWQNH
110 120 130 140 150
CRQMIMIRSI FLFLDRTYVL QNSMLPSIWD MGLELFRAHI ISDQKVQNKT
160 170 180 190 200
IDGILLLIER ERNGEAIDRS LLRSLLSMLS DLQIYQDSFE QRFLEETNRL
210 220 230
YAAEGQKLMQ EREVPEYLHH VNKRLEEEAD RLIT
Length:234
Mass (Da):27,889
Last modified:November 3, 2009 - v2
Checksum:iB0BF3D7EE3176777
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei234 – 2341Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002476 Genomic DNA. No translation available.
AL451005 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000371323; ENSP00000360374; ENSG00000158290.
UCSCiuc065axu.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002476 Genomic DNA. No translation available.
AL451005 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliA6NE76.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000384109.

Proteomic databases

EPDiA6NE76.
MaxQBiA6NE76.
PaxDbiA6NE76.
PRIDEiA6NE76.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000371323; ENSP00000360374; ENSG00000158290.
UCSCiuc065axu.1. human.

Organism-specific databases

HGNCiHGNC:2555. CUL4B.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2167. Eukaryota.
COG5647. LUCA.
GeneTreeiENSGT00760000119212.
HOGENOMiHOG000006909.
HOVERGENiHBG084579.

Miscellaneous databases

ChiTaRSiCUL4B. human.
NextBioi35462496.

Gene expression databases

BgeeiA6NE76.
ExpressionAtlasiA6NE76. baseline and differential.

Family and domain databases

InterProiIPR033044. CUL4B.
IPR001373. Cullin_N.
IPR016159. Cullin_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11932:SF66. PTHR11932:SF66. 1 hit.
PfamiPF00888. Cullin. 1 hit.
[Graphical view]
SUPFAMiSSF74788. SSF74788. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA6NE76_HUMAN
AccessioniPrimary (citable) accession number: A6NE76
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: November 3, 2009
Last modified: May 11, 2016
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.