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A6NE76

- A6NE76_HUMAN

UniProt

A6NE76 - A6NE76_HUMAN

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Protein
Submitted name:

Cullin-4B

Gene

CUL4B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. ubiquitin-dependent protein catabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cullin-4BImported
Gene namesi
Name:CUL4BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:2555. CUL4B.

Subcellular locationi

GO - Cellular componenti

  1. cullin-RING ubiquitin ligase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiA6NE76.
PRIDEiA6NE76.

Expressioni

Gene expression databases

BgeeiA6NE76.
ExpressionAtlasiA6NE76. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA6NE76.
SMRiA6NE76. Positions 15-234.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119212.
HOGENOMiHOG000006909.
HOVERGENiHBG084579.

Family and domain databases

InterProiIPR001373. Cullin_N.
IPR016159. Cullin_repeat-like_dom.
[Graphical view]
PfamiPF00888. Cullin. 1 hit.
[Graphical view]
SUPFAMiSSF74788. SSF74788. 1 hit.

Sequencei

Sequence statusi: Fragment.

A6NE76-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIDPDFADKP KLPENYTDET WQKLKEAVEA IQNSTSIKYN LEELYQAVEN
60 70 80 90 100
LCSYKISANL YKQLRQICED HIKAQIHQFR EDSLDSVLFL KKIDRCWQNH
110 120 130 140 150
CRQMIMIRSI FLFLDRTYVL QNSMLPSIWD MGLELFRAHI ISDQKVQNKT
160 170 180 190 200
IDGILLLIER ERNGEAIDRS LLRSLLSMLS DLQIYQDSFE QRFLEETNRL
210 220 230
YAAEGQKLMQ EREVPEYLHH VNKRLEEEAD RLIT
Length:234
Mass (Da):27,889
Last modified:November 3, 2009 - v2
Checksum:iB0BF3D7EE3176777
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei234 – 2341Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002476 Genomic DNA. No translation available.
AL451005 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000371323; ENSP00000360374; ENSG00000158290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002476 Genomic DNA. No translation available.
AL451005 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A6NE76.
SMRi A6NE76. Positions 15-234.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi A6NE76.
PRIDEi A6NE76.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000371323 ; ENSP00000360374 ; ENSG00000158290 .

Organism-specific databases

HGNCi HGNC:2555. CUL4B.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000119212.
HOGENOMi HOG000006909.
HOVERGENi HBG084579.

Miscellaneous databases

ChiTaRSi CUL4B. human.
NextBioi 35462496.

Gene expression databases

Bgeei A6NE76.
ExpressionAtlasi A6NE76. baseline and differential.

Family and domain databases

InterProi IPR001373. Cullin_N.
IPR016159. Cullin_repeat-like_dom.
[Graphical view ]
Pfami PF00888. Cullin. 1 hit.
[Graphical view ]
SUPFAMi SSF74788. SSF74788. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA6NE76_HUMAN
AccessioniPrimary (citable) accession number: A6NE76
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: November 3, 2009
Last modified: November 26, 2014
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3