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Protein

BTB/POZ domain-containing protein 17

Gene

BTBD17

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciZFISH:G66-32504-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
BTB/POZ domain-containing protein 17
Alternative name(s):
Galectin-3-binding protein-like
Gene namesi
Name:BTBD17
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:33758. BTBD17.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204347.
PharmGKBiPA162377627.

Polymorphism and mutation databases

BioMutaiBTBD17.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000034070429 – 478BTB/POZ domain-containing protein 17Add BLAST450

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi61N-linked (GlcNAc...)Sequence analysis1
Glycosylationi100N-linked (GlcNAc...)Sequence analysis1
Glycosylationi195N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiA6NE02.
PRIDEiA6NE02.

PTM databases

iPTMnetiA6NE02.
PhosphoSitePlusiA6NE02.

Expressioni

Gene expression databases

BgeeiENSG00000204347.
CleanExiHS_BTBD17.
GenevisibleiA6NE02. HS.

Organism-specific databases

HPAiHPA025022.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000364515.

Structurei

3D structure databases

ProteinModelPortaliA6NE02.
SMRiA6NE02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 132BTBPROSITE-ProRule annotationAdd BLAST70
Domaini169 – 269BACKAdd BLAST101

Sequence similaritiesi

Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG2075. Eukaryota.
ENOG410XQ3X. LUCA.
GeneTreeiENSGT00530000063814.
HOGENOMiHOG000095275.
HOVERGENiHBG060469.
InParanoidiA6NE02.
OMAiWGAPWVI.
OrthoDBiEOG091G0MFZ.
PhylomeDBiA6NE02.
TreeFamiTF331368.

Family and domain databases

InterProiIPR011705. BACK.
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6NE02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRRGYSKPG SWGSFWAMLT LVGLVTHAAQ RADVGGEAAG TSINHSQAVL
60 70 80 90 100
QRLQELLRQG NASDVVLRVQ AAGTDEVRVF HAHRLLLGLH SELFLELLSN
110 120 130 140 150
QSEAVLQEPQ DCAAVFDKFI RYLYCGELTV LLTQAIPLHR LATKYGVSSL
160 170 180 190 200
QRGVADYMRA HLAGGAGPAV GWYHYAVGTG DEALRESCLQ FLAWNLSAVA
210 220 230 240 250
ASTEWGAVSP ELLWQLLQRS DLVLQDELEL FHALEAWLGR ARPPPAVAER
260 270 280 290 300
ALRAIRYPMI PPAQLFQLQA RSAALARHGP AVADLLLQAY QFHAASPLHY
310 320 330 340 350
AKFFDVNGSA FLPRNYLAPA WGAPWVINNP ARDDRSTSFQ TQLGPSGHDA
360 370 380 390 400
GRRVTWNVLF SPRWLPVSLR PVYADAAGTA LPAARPEDGR PRLVVTPASS
410 420 430 440 450
GGDAAGVSFQ KTVLVGARQQ GRLLVRHAYS FHQSSEEAGD FLAHADLQRR
460 470
NSEYLVENAL HLHLIVKPVY HTLIRTPK
Length:478
Mass (Da):52,471
Last modified:July 24, 2007 - v1
Checksum:iA0D574BECE1A0D05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103809 Genomic DNA. No translation available.
CH471099 Genomic DNA. Translation: EAW89155.1.
CCDSiCCDS32719.1.
RefSeqiNP_001073935.1. NM_001080466.1.
UniGeneiHs.211870.

Genome annotation databases

EnsembliENST00000375366; ENSP00000364515; ENSG00000204347.
GeneIDi388419.
KEGGihsa:388419.
UCSCiuc002jkn.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103809 Genomic DNA. No translation available.
CH471099 Genomic DNA. Translation: EAW89155.1.
CCDSiCCDS32719.1.
RefSeqiNP_001073935.1. NM_001080466.1.
UniGeneiHs.211870.

3D structure databases

ProteinModelPortaliA6NE02.
SMRiA6NE02.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000364515.

PTM databases

iPTMnetiA6NE02.
PhosphoSitePlusiA6NE02.

Polymorphism and mutation databases

BioMutaiBTBD17.

Proteomic databases

PaxDbiA6NE02.
PRIDEiA6NE02.

Protocols and materials databases

DNASUi388419.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375366; ENSP00000364515; ENSG00000204347.
GeneIDi388419.
KEGGihsa:388419.
UCSCiuc002jkn.3. human.

Organism-specific databases

CTDi388419.
GeneCardsiBTBD17.
HGNCiHGNC:33758. BTBD17.
HPAiHPA025022.
neXtProtiNX_A6NE02.
OpenTargetsiENSG00000204347.
PharmGKBiPA162377627.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2075. Eukaryota.
ENOG410XQ3X. LUCA.
GeneTreeiENSGT00530000063814.
HOGENOMiHOG000095275.
HOVERGENiHBG060469.
InParanoidiA6NE02.
OMAiWGAPWVI.
OrthoDBiEOG091G0MFZ.
PhylomeDBiA6NE02.
TreeFamiTF331368.

Enzyme and pathway databases

BioCyciZFISH:G66-32504-MONOMER.

Miscellaneous databases

GenomeRNAii388419.
PROiA6NE02.

Gene expression databases

BgeeiENSG00000204347.
CleanExiHS_BTBD17.
GenevisibleiA6NE02. HS.

Family and domain databases

InterProiIPR011705. BACK.
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBTBDH_HUMAN
AccessioniPrimary (citable) accession number: A6NE02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: July 24, 2007
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.