ID   MYADL_HUMAN             Reviewed;         303 AA.
AC   A6NDP7;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   22-JUL-2008, entry version 11.
DE   RecName: Full=Myeloid-associated differentiation marker-like protein;
GN   Name=MYADML;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain, and Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Belongs to the MAL family.
CC   -!- SIMILARITY: Contains 2 MARVEL domains.
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DR   EMBL; AC137723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC029306; -; NOT_ANNOTATED_CDS; mRNA.
DR   UniGene; Hs.163451; -.
DR   Ensembl; ENSG00000185105; Homo sapiens.
DR   KEGG; hsa:255275; -.
DR   InterPro; IPR008253; Marvel.
DR   Pfam; PF01284; MARVEL; 2.
DR   PROSITE; PS51225; MARVEL; 2.
PE   2: Evidence at transcript level;
KW   Membrane; Repeat; Transmembrane.
FT   CHAIN         1    303       Myeloid-associated differentiation
FT                                marker-like protein.
FT                                /FTId=PRO_0000332206.
FT   TRANSMEM     49     69       Potential.
FT   TRANSMEM     86    106       Potential.
FT   TRANSMEM    125    145       Potential.
FT   TRANSMEM    159    179       Potential.
FT   TRANSMEM    194    214       Potential.
FT   TRANSMEM    225    245       Potential.
FT   TRANSMEM    274    294       Potential.
FT   DOMAIN       13    150       MARVEL 1.
FT   DOMAIN      155    299       MARVEL 2.
FT   CONFLICT    112    112       S -> P (in Ref. 2; BC029306).
FT   CONFLICT    225    225       W -> R (in Ref. 2; BC029306).
SQ   SEQUENCE   303 AA;  32620 MW;  A5D1B2A05E455FA5 CRC64;
     MEPPGGAYLH LGAVTSPVGT ARVLQLAFGC TTFSLVAHRG GFAGVQGTFC MAAWGFCFAV
     SALVVACEFT RLHGCLRLSW GNFTAAFAML ATLLCATAAV LYPLYFARRE CSPEPAGCAA
     RDFRLAASVF AGLLFLAYAV EVALTRARPG QVSSYMATVS GLLKIVQAFV ACIIFGALVH
     DSRYGRYVAT QWCVAVYSLC FLATVAVVAL SVMGHTGGLG CPFDWLVVVY TFLAVLLYLS
     AAVIWPVFCF DPKYGEPKRP PNCARGSCPW DSQLVVAIFT YVNLLLYVVD LAYSQRIRFV
     PSL
//