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Protein

Golgin subfamily A member 6B

Gene

GOLGA6B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 6B
Gene namesi
Name:GOLGA6B
Synonyms:GOLGA
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:32205. GOLGA6B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162389878.

Polymorphism and mutation databases

BioMutaiGOLGA6B.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 693693Golgin subfamily A member 6BPRO_0000332248Add
BLAST

Proteomic databases

EPDiA6NDN3.
PaxDbiA6NDN3.
PRIDEiA6NDN3.

PTM databases

iPTMnetiA6NDN3.

Expressioni

Gene expression databases

BgeeiA6NDN3.
GenevisibleiA6NDN3. HS.

Organism-specific databases

HPAiHPA044978.
HPA045056.
HPA050087.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000408132.

Structurei

3D structure databases

ProteinModelPortaliA6NDN3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili77 – 611535Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the GOLGA6 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4725. Eukaryota.
ENOG410ZIE4. LUCA.
GeneTreeiENSGT00530000062932.
HOGENOMiHOG000218631.
HOVERGENiHBG051752.
InParanoidiA6NDN3.
OMAiHIELNAT.
OrthoDBiEOG71P29T.
PhylomeDBiA6NDN3.
TreeFamiTF316990.

Family and domain databases

InterProiIPR024858. Golgin_A.
[Graphical view]
PfamiPF15070. GOLGA2L5. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6NDN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWPQPYLPPH PMMLEESRQN KLAAAKKKLK EYQQRKSPGI PAGAKTKKKK
60 70 80 90 100
TDSSPETTTS GGGHSPGDSQ YQELAVALES SSVTISQLNE NIESLKQQKK
110 120 130 140 150
QVEHQLEEAK KTNNEIHKAQ MERLETINIL TLEKADLKTT LYHTKRAARH
160 170 180 190 200
FEEESKDLAG RLQYSLQRIQ ELERALCAVS TQQQEEDRSS SCREAVLHRR
210 220 230 240 250
LQQTIKERAL LNAHVTQVTE SLKQVQLERD EYAKHIKGER ARWQERMWKM
260 270 280 290 300
SVEARTLKEE KKRDIHRIQE LERSLSELKN QMAKPPSLAP PAVTSVVEQL
310 320 330 340 350
QDEAKHLRQE VEGLEGKLQS QVENNQALSL LSKEQKQRLQ EQEEMLREQE
360 370 380 390 400
VQRVREQERL CEQNERLREQ QKTLQEQGER LRKQEQRLRK QEERLRKEEE
410 420 430 440 450
RLQKQEKRLW DQEERLWKKE ERLQKQEERL ALSQNHKLDK QLAEPQCSFE
460 470 480 490 500
DLNNEKKSAL QLEQQVKELQ EKLDEEHLEA ASQQNQQLET QLSLVALPGE
510 520 530 540 550
GDGGQHLDSE EEEAPRPTPN IPEDLESREA TSSFMDLPKE KADGTEQVER
560 570 580 590 600
RELGFVQPSG VTDGMRESFT VYESQGAVPN TRHQEMEDVI RLAQKEEEMK
610 620 630 640 650
VKLLELQELV LPLVGNHEGH GKFLIAAQNP ADEPTPGAPA PQELGAAGEQ
660 670 680 690
DDFYEVSLDN NVEPAPGAAR EGSPHDNPTV QQIVQLSPVM QDT
Length:693
Mass (Da):79,913
Last modified:April 29, 2008 - v3
Checksum:i462832EB3A4DB159
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti200 – 2001R → W.
Corresponds to variant rs2081561 [ dbSNP | Ensembl ].
VAR_042994

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009712 Genomic DNA. No translation available.
AC100827 Genomic DNA. No translation available.
CCDSiCCDS10245.2.
RefSeqiNP_061122.4. NM_018652.4.
UniGeneiHs.546408.

Genome annotation databases

EnsembliENST00000421285; ENSP00000408132; ENSG00000215186.
GeneIDi55889.
KEGGihsa:55889.
UCSCiuc010uks.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009712 Genomic DNA. No translation available.
AC100827 Genomic DNA. No translation available.
CCDSiCCDS10245.2.
RefSeqiNP_061122.4. NM_018652.4.
UniGeneiHs.546408.

3D structure databases

ProteinModelPortaliA6NDN3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000408132.

PTM databases

iPTMnetiA6NDN3.

Polymorphism and mutation databases

BioMutaiGOLGA6B.

Proteomic databases

EPDiA6NDN3.
PaxDbiA6NDN3.
PRIDEiA6NDN3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000421285; ENSP00000408132; ENSG00000215186.
GeneIDi55889.
KEGGihsa:55889.
UCSCiuc010uks.2. human.

Organism-specific databases

CTDi55889.
GeneCardsiGOLGA6B.
HGNCiHGNC:32205. GOLGA6B.
HPAiHPA044978.
HPA045056.
HPA050087.
neXtProtiNX_A6NDN3.
PharmGKBiPA162389878.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4725. Eukaryota.
ENOG410ZIE4. LUCA.
GeneTreeiENSGT00530000062932.
HOGENOMiHOG000218631.
HOVERGENiHBG051752.
InParanoidiA6NDN3.
OMAiHIELNAT.
OrthoDBiEOG71P29T.
PhylomeDBiA6NDN3.
TreeFamiTF316990.

Miscellaneous databases

GenomeRNAii55889.
NextBioi61224.

Gene expression databases

BgeeiA6NDN3.
GenevisibleiA6NDN3. HS.

Family and domain databases

InterProiIPR024858. Golgin_A.
[Graphical view]
PfamiPF15070. GOLGA2L5. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiGOG6B_HUMAN
AccessioniPrimary (citable) accession number: A6NDN3
Secondary accession number(s): A8MYY7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: March 16, 2016
This is version 62 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Maps to a duplicated region on chromosome 15; the gene is present in at least 4 almost identical copies.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.