Reviewed, UniProtKB/Swiss-Prot A6NCL7 (AN33B_HUMAN)

Names and origin

Protein names

Recommended name:
    Ankyrin repeat domain-containing protein 33B

Gene names

Name:

ANKRD33B

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	494 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Coiled coil Repeat
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 494	494	Ankyrin repeat domain-containing protein 33B		PRO_0000328769
Regions
	Repeat	84 – 113	30	ANK 1
	Repeat	120 – 150	31	ANK 2
	Repeat	154 – 183	30	ANK 3
	Repeat	189 – 218	30	ANK 4
	Repeat	223 – 255	33	ANK 5
	Coiled coil	459 – 488	30	Potential
	Compositional bias	19 – 25	7	Poly-Pro
	Compositional bias	264 – 267	4	Poly-Pro

Sequences

	Sequence		Length	Mass (Da)
	A6NCL7-1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 18723DD152CBDB14	FASTA	494	53,975
	10 20 30 40 50 60 MVLLAGTGPE GGGARCMTPP PPSPPRGAQV EEDPADYEEF EDFSSLPDTR SIASDDSFYP 70 80 90 100 110 120 FEDEEEHGVE SAESVPEGVP ESVPETATLL RAACANNVGL LRTLVRRGVS VEEAQETDRN 130 140 150 160 170 180 GRTGLIVACY HGFVDTVVAL AECPHVDVNW QDSEGNTALI TAAQAGHAII TNYLLNYFPG 190 200 210 220 230 240 LDLERRNAFG FTALMKAAMQ GRTDCIRALM LAGADVHARD PRRGMSPQEW ATYTGRVDAV 250 260 270 280 290 300 RLMQRLLERP CPEQFWEKYR PELPPPPEAA RKPAGSKNCL QRLTDCVLSV LTPRSVRGPE 310 320 330 340 350 360 DGGVLDHMVR MTTSLYSPAV AIVCQTVCPE SPPSVGKRRL AVQEILAARA ARGPQAQEED 370 380 390 400 410 420 EVGGAGQRGR TGQEDADSRE GSPRAGLPPA LGSRGPAAPA PRKASLLPLQ RLRRRSVRPG 430 440 450 460 470 480 VVVPRVRVSK APAPTFQPER PARKGSTKDS GHLQIPKWRY KEAKEEKRKA EEAEKKRQAE 490 AQKERRTAPW KKRT

References

[1]

"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M. Nature 431:268-274(2004) [PubMed: 15372022] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC112200 Genomic DNA. No translation available.
IPI	IPI00235708.
RefSeq	NP_001157912.1. XP_001723826.1.
UniGene	Hs.680828
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENST00000296657; ENSP00000296657; ENSG00000164236; Homo sapiens. [Genome view]
GeneID	651746.
KEGG	hsa:651746.
Organism-specific databases
CTD	651746.
GeneCards	GC05P010616.
HGNC	HGNC:35240. ANKRD33B.
GenAtlas	Search...
Phylogenomic databases
OMA	VCPESPP
OrthoDB	EOG9H48NZ
Gene expression databases
Genevestigator	A6NCL7.
Family and domain databases
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. [Graphical view]
Pfam	PF00023. Ank. 3 hits. [Graphical view]
SMART	SM00248. ANK. 5 hits. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	121730.

Entry information

Entry name

AN33B_HUMAN

Accession

Primary (citable) accession number: A6NCL7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	July 24, 2007
Last modified:	November 24, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.