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A6NCL7 (AN33B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ankyrin repeat domain-containing protein 33B
Gene names
Name:ANKRD33B
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length494 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Ontologies

Keywords
   DomainANK repeat
Coiled coil
Repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 494494Ankyrin repeat domain-containing protein 33B
PRO_0000328769

Regions

Repeat84 – 11330ANK 1
Repeat120 – 15031ANK 2
Repeat154 – 18330ANK 3
Repeat189 – 21830ANK 4
Repeat223 – 25533ANK 5
Coiled coil459 – 48830 Potential
Compositional bias19 – 257Poly-Pro
Compositional bias264 – 2674Poly-Pro

Sequences

Sequence LengthMass (Da)Tools
A6NCL7 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 18723DD152CBDB14

FASTA49453,975
        10         20         30         40         50         60 
MVLLAGTGPE GGGARCMTPP PPSPPRGAQV EEDPADYEEF EDFSSLPDTR SIASDDSFYP 

        70         80         90        100        110        120 
FEDEEEHGVE SAESVPEGVP ESVPETATLL RAACANNVGL LRTLVRRGVS VEEAQETDRN 

       130        140        150        160        170        180 
GRTGLIVACY HGFVDTVVAL AECPHVDVNW QDSEGNTALI TAAQAGHAII TNYLLNYFPG 

       190        200        210        220        230        240 
LDLERRNAFG FTALMKAAMQ GRTDCIRALM LAGADVHARD PRRGMSPQEW ATYTGRVDAV 

       250        260        270        280        290        300 
RLMQRLLERP CPEQFWEKYR PELPPPPEAA RKPAGSKNCL QRLTDCVLSV LTPRSVRGPE 

       310        320        330        340        350        360 
DGGVLDHMVR MTTSLYSPAV AIVCQTVCPE SPPSVGKRRL AVQEILAARA ARGPQAQEED 

       370        380        390        400        410        420 
EVGGAGQRGR TGQEDADSRE GSPRAGLPPA LGSRGPAAPA PRKASLLPLQ RLRRRSVRPG 

       430        440        450        460        470        480 
VVVPRVRVSK APAPTFQPER PARKGSTKDS GHLQIPKWRY KEAKEEKRKA EEAEKKRQAE 

       490 
AQKERRTAPW KKRT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC112200 Genomic DNA. No translation available.
CCDSCCDS47191.1.
RefSeqNP_001157912.1. NM_001164440.1.
UniGeneHs.26039.

3D structure databases

ProteinModelPortalA6NCL7.
SMRA6NCL7. Positions 89-244.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteA6NCL7.

Proteomic databases

PaxDbA6NCL7.
PRIDEA6NCL7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000296657; ENSP00000296657; ENSG00000164236.
GeneID651746.
KEGGhsa:651746.
UCSCuc021xwp.1. human.

Organism-specific databases

CTD651746.
GeneCardsGC05P010564.
HGNCHGNC:35240. ANKRD33B.
HPAHPA056974.
neXtProtNX_A6NCL7.
PharmGKBPA164715326.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0666.
HOGENOMHOG000033933.
HOVERGENHBG095573.
InParanoidA6NCL7.
OMAQGRTECV.
PhylomeDBA6NCL7.
TreeFamTF332022.

Gene expression databases

ArrayExpressA6NCL7.
BgeeA6NCL7.
GenevestigatorA6NCL7.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamPF00023. Ank. 1 hit.
PF12796. Ank_2. 1 hit.
[Graphical view]
SMARTSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi651746.
NextBio121730.
PROA6NCL7.

Entry information

Entry nameAN33B_HUMAN
AccessionPrimary (citable) accession number: A6NCL7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 24, 2007
Last modified: July 9, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 5

Human chromosome 5: entries, gene names and cross-references to MIM