Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ankyrin repeat domain-containing protein 33B

Gene

ANKRD33B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 33B
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000164236.11.
HGNCiHGNC:35240. ANKRD33B.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164236.
PharmGKBiPA164715326.

Polymorphism and mutation databases

BioMutaiANKRD33B.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003287691 – 494Ankyrin repeat domain-containing protein 33BAdd BLAST494

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei405PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiA6NCL7.
PaxDbiA6NCL7.
PRIDEiA6NCL7.

PTM databases

iPTMnetiA6NCL7.
PhosphoSitePlusiA6NCL7.

Expressioni

Gene expression databases

BgeeiENSG00000164236.
ExpressionAtlasiA6NCL7. baseline and differential.
GenevisibleiA6NCL7. HS.

Organism-specific databases

HPAiHPA056974.

Interactioni

Protein-protein interaction databases

BioGridi574599. 2 interactors.

Structurei

3D structure databases

ProteinModelPortaliA6NCL7.
SMRiA6NCL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati84 – 113ANK 1Add BLAST30
Repeati120 – 150ANK 2Add BLAST31
Repeati154 – 183ANK 3Add BLAST30
Repeati189 – 218ANK 4Add BLAST30
Repeati223 – 255ANK 5Add BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili459 – 488Sequence analysisAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi19 – 25Poly-Pro7
Compositional biasi264 – 267Poly-Pro4

Keywords - Domaini

ANK repeat, Coiled coil, Repeat

Phylogenomic databases

eggNOGiENOG410IFWP. Eukaryota.
ENOG4111JDG. LUCA.
GeneTreeiENSGT00500000044852.
HOGENOMiHOG000033933.
HOVERGENiHBG095573.
InParanoidiA6NCL7.
OMAiKDSAHLQ.
OrthoDBiEOG091G0WU0.
PhylomeDBiA6NCL7.
TreeFamiTF332022.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
SMARTiView protein in SMART
SM00248. ANK. 5 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NCL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLLAGTGPE GGGARCMTPP PPSPPRGAQV EEDPADYEEF EDFSSLPDTR
60 70 80 90 100
SIASDDSFYP FEDEEEHGVE SAESVPEGVP ESVPETATLL RAACANNVGL
110 120 130 140 150
LRTLVRRGVS VEEAQETDRN GRTGLIVACY HGFVDTVVAL AECPHVDVNW
160 170 180 190 200
QDSEGNTALI TAAQAGHAII TNYLLNYFPG LDLERRNAFG FTALMKAAMQ
210 220 230 240 250
GRTDCIRALM LAGADVHARD PRRGMSPQEW ATYTGRVDAV RLMQRLLERP
260 270 280 290 300
CPEQFWEKYR PELPPPPEAA RKPAGSKNCL QRLTDCVLSV LTPRSVRGPE
310 320 330 340 350
DGGVLDHMVR MTTSLYSPAV AIVCQTVCPE SPPSVGKRRL AVQEILAARA
360 370 380 390 400
ARGPQAQEED EVGGAGQRGR TGQEDADSRE GSPRAGLPPA LGSRGPAAPA
410 420 430 440 450
PRKASLLPLQ RLRRRSVRPG VVVPRVRVSK APAPTFQPER PARKGSTKDS
460 470 480 490
GHLQIPKWRY KEAKEEKRKA EEAEKKRQAE AQKERRTAPW KKRT
Length:494
Mass (Da):53,975
Last modified:July 24, 2007 - v1
Checksum:i18723DD152CBDB14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112200 Genomic DNA. No translation available.
CCDSiCCDS47191.1.
RefSeqiNP_001157912.1. NM_001164440.1.
UniGeneiHs.26039.

Genome annotation databases

EnsembliENST00000296657; ENSP00000296657; ENSG00000164236.
GeneIDi651746.
KEGGihsa:651746.
UCSCiuc021xwp.2. human.

Similar proteinsi

Entry informationi

Entry nameiAN33B_HUMAN
AccessioniPrimary (citable) accession number: A6NCL7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 24, 2007
Last modified: September 27, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM