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A6NCL7

- AN33B_HUMAN

UniProt

A6NCL7 - AN33B_HUMAN

Protein

Ankyrin repeat domain-containing protein 33B

Gene

ANKRD33B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (24 Jul 2007)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ankyrin repeat domain-containing protein 33B
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:35240. ANKRD33B.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164715326.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 494494Ankyrin repeat domain-containing protein 33BPRO_0000328769Add
    BLAST

    Proteomic databases

    PaxDbiA6NCL7.
    PRIDEiA6NCL7.

    PTM databases

    PhosphoSiteiA6NCL7.

    Expressioni

    Gene expression databases

    ArrayExpressiA6NCL7.
    BgeeiA6NCL7.
    GenevestigatoriA6NCL7.

    Organism-specific databases

    HPAiHPA056974.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NCL7.
    SMRiA6NCL7. Positions 89-244.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati84 – 11330ANK 1Add
    BLAST
    Repeati120 – 15031ANK 2Add
    BLAST
    Repeati154 – 18330ANK 3Add
    BLAST
    Repeati189 – 21830ANK 4Add
    BLAST
    Repeati223 – 25533ANK 5Add
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili459 – 48830Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi19 – 257Poly-Pro
    Compositional biasi264 – 2674Poly-Pro

    Sequence similaritiesi

    Contains 5 ANK repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    ANK repeat, Coiled coil, Repeat

    Phylogenomic databases

    eggNOGiCOG0666.
    HOGENOMiHOG000033933.
    HOVERGENiHBG095573.
    InParanoidiA6NCL7.
    OMAiQGRTECV.
    PhylomeDBiA6NCL7.
    TreeFamiTF332022.

    Family and domain databases

    Gene3Di1.25.40.20. 1 hit.
    InterProiIPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    [Graphical view]
    PfamiPF00023. Ank. 1 hit.
    PF12796. Ank_2. 1 hit.
    [Graphical view]
    SMARTiSM00248. ANK. 5 hits.
    [Graphical view]
    SUPFAMiSSF48403. SSF48403. 1 hit.
    PROSITEiPS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6NCL7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVLLAGTGPE GGGARCMTPP PPSPPRGAQV EEDPADYEEF EDFSSLPDTR    50
    SIASDDSFYP FEDEEEHGVE SAESVPEGVP ESVPETATLL RAACANNVGL 100
    LRTLVRRGVS VEEAQETDRN GRTGLIVACY HGFVDTVVAL AECPHVDVNW 150
    QDSEGNTALI TAAQAGHAII TNYLLNYFPG LDLERRNAFG FTALMKAAMQ 200
    GRTDCIRALM LAGADVHARD PRRGMSPQEW ATYTGRVDAV RLMQRLLERP 250
    CPEQFWEKYR PELPPPPEAA RKPAGSKNCL QRLTDCVLSV LTPRSVRGPE 300
    DGGVLDHMVR MTTSLYSPAV AIVCQTVCPE SPPSVGKRRL AVQEILAARA 350
    ARGPQAQEED EVGGAGQRGR TGQEDADSRE GSPRAGLPPA LGSRGPAAPA 400
    PRKASLLPLQ RLRRRSVRPG VVVPRVRVSK APAPTFQPER PARKGSTKDS 450
    GHLQIPKWRY KEAKEEKRKA EEAEKKRQAE AQKERRTAPW KKRT 494
    Length:494
    Mass (Da):53,975
    Last modified:July 24, 2007 - v1
    Checksum:i18723DD152CBDB14
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC112200 Genomic DNA. No translation available.
    CCDSiCCDS47191.1.
    RefSeqiNP_001157912.1. NM_001164440.1.
    UniGeneiHs.26039.

    Genome annotation databases

    EnsembliENST00000296657; ENSP00000296657; ENSG00000164236.
    GeneIDi651746.
    KEGGihsa:651746.
    UCSCiuc021xwp.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC112200 Genomic DNA. No translation available.
    CCDSi CCDS47191.1.
    RefSeqi NP_001157912.1. NM_001164440.1.
    UniGenei Hs.26039.

    3D structure databases

    ProteinModelPortali A6NCL7.
    SMRi A6NCL7. Positions 89-244.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei A6NCL7.

    Proteomic databases

    PaxDbi A6NCL7.
    PRIDEi A6NCL7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000296657 ; ENSP00000296657 ; ENSG00000164236 .
    GeneIDi 651746.
    KEGGi hsa:651746.
    UCSCi uc021xwp.1. human.

    Organism-specific databases

    CTDi 651746.
    GeneCardsi GC05P010564.
    HGNCi HGNC:35240. ANKRD33B.
    HPAi HPA056974.
    neXtProti NX_A6NCL7.
    PharmGKBi PA164715326.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0666.
    HOGENOMi HOG000033933.
    HOVERGENi HBG095573.
    InParanoidi A6NCL7.
    OMAi QGRTECV.
    PhylomeDBi A6NCL7.
    TreeFami TF332022.

    Miscellaneous databases

    GenomeRNAii 651746.
    NextBioi 121730.
    PROi A6NCL7.

    Gene expression databases

    ArrayExpressi A6NCL7.
    Bgeei A6NCL7.
    Genevestigatori A6NCL7.

    Family and domain databases

    Gene3Di 1.25.40.20. 1 hit.
    InterProi IPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    [Graphical view ]
    Pfami PF00023. Ank. 1 hit.
    PF12796. Ank_2. 1 hit.
    [Graphical view ]
    SMARTi SM00248. ANK. 5 hits.
    [Graphical view ]
    SUPFAMi SSF48403. SSF48403. 1 hit.
    PROSITEi PS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiAN33B_HUMAN
    AccessioniPrimary (citable) accession number: A6NCL7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 5
      Human chromosome 5: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3