Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein C10orf131

Gene

C10orf131

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C10orf131
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:31667. C10orf131.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134931868.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 256256Uncharacterized protein C10orf131PRO_0000320923Add
BLAST

Proteomic databases

PaxDbiA6NCD4.
PRIDEiA6NCD4.

Expressioni

Gene expression databases

BgeeiA6NCD4.
GenevestigatoriA6NCD4.

Structurei

3D structure databases

ProteinModelPortaliA6NCD4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili136 – 15924Sequence AnalysisAdd
BLAST
Coiled coili194 – 21421Sequence AnalysisAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG255795.
GeneTreeiENSGT00510000046611.
HOGENOMiHOG000111716.
HOVERGENiHBG098298.
InParanoidiA6NCD4.
OrthoDBiEOG7X3QQ6.
PhylomeDBiA6NCD4.
TreeFamiTF333815.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: A6NCD4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSEEMDNITA EEIIDKHLQK DLDAEENQNV AKTLRGKVRE KLKISKINKG
60 70 80 90 100
EKSSTEQLID SEIHQRSKLS PQTEVSLDES LSFFILSGEE GSALGKSSEQ
110 120 130 140 150
RPVNRSYPKC FSLGVNLQNV AESEEEEFMK EFILTDILKV KAADYEDDQE
160 170 180 190 200
QIKKQKANIF VPSSSPVVNQ RKLPKDMMPR ILEDEGFYIQ RKPEIYKKTC
210 220 230 240 250
NKMENRLLKL EEAKCWFGES GEIMSLPTPI KQSWNFRLNV RKEPLNPLLK

TIYRKL
Length:256
Mass (Da):29,615
Last modified:July 22, 2008 - v3
Checksum:i9418473D2366F675
GO
Isoform 2 (identifier: A6NCD4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MGVQM
     167-256: VVNQRKLPKD...PLLKTIYRKL → GNILSQ

Show »
Length:176
Mass (Da):19,808
Checksum:i9765C52C1E321CD2
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MGVQM in isoform 2. 1 PublicationVSP_045322
Alternative sequencei167 – 25690VVNQR…IYRKL → GNILSQ in isoform 2. 1 PublicationVSP_045323Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK294399 mRNA. Translation: BAG57652.1.
AL513355, AL356155 Genomic DNA. Translation: CAH71690.1.
AL356155, AL513355 Genomic DNA. Translation: CAI16400.1.
CCDSiCCDS58090.1. [A6NCD4-2]
RefSeqiNP_001123918.2. NM_001130446.2. [A6NCD4-2]
UniGeneiHs.719076.

Genome annotation databases

EnsembliENST00000423344; ENSP00000411850; ENSG00000173088. [A6NCD4-2]
GeneIDi100127889.
KEGGihsa:100127889.
UCSCiuc010qoo.2. human.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK294399 mRNA. Translation: BAG57652.1.
AL513355, AL356155 Genomic DNA. Translation: CAH71690.1.
AL356155, AL513355 Genomic DNA. Translation: CAI16400.1.
CCDSiCCDS58090.1. [A6NCD4-2]
RefSeqiNP_001123918.2. NM_001130446.2. [A6NCD4-2]
UniGeneiHs.719076.

3D structure databases

ProteinModelPortaliA6NCD4.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiA6NCD4.
PRIDEiA6NCD4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000423344; ENSP00000411850; ENSG00000173088. [A6NCD4-2]
GeneIDi100127889.
KEGGihsa:100127889.
UCSCiuc010qoo.2. human.

Organism-specific databases

CTDi100127889.
GeneCardsiGC10P097667.
HGNCiHGNC:31667. C10orf131.
neXtProtiNX_A6NCD4.
PharmGKBiPA134931868.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG255795.
GeneTreeiENSGT00510000046611.
HOGENOMiHOG000111716.
HOVERGENiHBG098298.
InParanoidiA6NCD4.
OrthoDBiEOG7X3QQ6.
PhylomeDBiA6NCD4.
TreeFamiTF333815.

Miscellaneous databases

GenomeRNAii100127889.
NextBioi20789158.

Gene expression databases

BgeeiA6NCD4.
GenevestigatoriA6NCD4.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Amygdala.
  2. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCJ131_HUMAN
AccessioniPrimary (citable) accession number: A6NCD4
Secondary accession number(s): B1AMZ2, B4DG41
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 22, 2008
Last modified: January 7, 2015
This is version 52 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.