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A6NCD4

- CJ131_HUMAN

UniProt

A6NCD4 - CJ131_HUMAN

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Protein

Uncharacterized protein C10orf131

Gene
C10orf131
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C10orf131
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:31667. C10orf131.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134931868.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 256256Uncharacterized protein C10orf131PRO_0000320923Add
BLAST

Proteomic databases

PaxDbiA6NCD4.
PRIDEiA6NCD4.

Expressioni

Gene expression databases

BgeeiA6NCD4.
GenevestigatoriA6NCD4.

Structurei

3D structure databases

ProteinModelPortaliA6NCD4.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili136 – 15924 Reviewed predictionAdd
BLAST
Coiled coili194 – 21421 Reviewed predictionAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG255795.
HOGENOMiHOG000111716.
HOVERGENiHBG098298.
InParanoidiA6NCD4.
OrthoDBiEOG7X3QQ6.
PhylomeDBiA6NCD4.
TreeFamiTF333815.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: A6NCD4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSEEMDNITA EEIIDKHLQK DLDAEENQNV AKTLRGKVRE KLKISKINKG    50
EKSSTEQLID SEIHQRSKLS PQTEVSLDES LSFFILSGEE GSALGKSSEQ 100
RPVNRSYPKC FSLGVNLQNV AESEEEEFMK EFILTDILKV KAADYEDDQE 150
QIKKQKANIF VPSSSPVVNQ RKLPKDMMPR ILEDEGFYIQ RKPEIYKKTC 200
NKMENRLLKL EEAKCWFGES GEIMSLPTPI KQSWNFRLNV RKEPLNPLLK 250
TIYRKL 256
Length:256
Mass (Da):29,615
Last modified:July 22, 2008 - v3
Checksum:i9418473D2366F675
GO
Isoform 2 (identifier: A6NCD4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MGVQM
     167-256: VVNQRKLPKD...PLLKTIYRKL → GNILSQ

Show »
Length:176
Mass (Da):19,808
Checksum:i9765C52C1E321CD2
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MGVQM in isoform 2. VSP_045322
Alternative sequencei167 – 25690VVNQR…IYRKL → GNILSQ in isoform 2. VSP_045323Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK294399 mRNA. Translation: BAG57652.1.
AL513355, AL356155 Genomic DNA. Translation: CAH71690.1.
AL356155, AL513355 Genomic DNA. Translation: CAI16400.1.
CCDSiCCDS58090.1. [A6NCD4-2]
RefSeqiNP_001123918.2. NM_001130446.2. [A6NCD4-2]
UniGeneiHs.719076.

Genome annotation databases

EnsembliENST00000423344; ENSP00000411850; ENSG00000173088. [A6NCD4-2]
GeneIDi100127889.
KEGGihsa:100127889.
UCSCiuc010qoo.2. human.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK294399 mRNA. Translation: BAG57652.1 .
AL513355 , AL356155 Genomic DNA. Translation: CAH71690.1 .
AL356155 , AL513355 Genomic DNA. Translation: CAI16400.1 .
CCDSi CCDS58090.1. [A6NCD4-2 ]
RefSeqi NP_001123918.2. NM_001130446.2. [A6NCD4-2 ]
UniGenei Hs.719076.

3D structure databases

ProteinModelPortali A6NCD4.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi A6NCD4.
PRIDEi A6NCD4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000423344 ; ENSP00000411850 ; ENSG00000173088 . [A6NCD4-2 ]
GeneIDi 100127889.
KEGGi hsa:100127889.
UCSCi uc010qoo.2. human.

Organism-specific databases

CTDi 100127889.
GeneCardsi GC10P097667.
HGNCi HGNC:31667. C10orf131.
neXtProti NX_A6NCD4.
PharmGKBi PA134931868.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG255795.
HOGENOMi HOG000111716.
HOVERGENi HBG098298.
InParanoidi A6NCD4.
OrthoDBi EOG7X3QQ6.
PhylomeDBi A6NCD4.
TreeFami TF333815.

Miscellaneous databases

GenomeRNAii 100127889.
NextBioi 20789158.

Gene expression databases

Bgeei A6NCD4.
Genevestigatori A6NCD4.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Amygdala.
  2. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCJ131_HUMAN
AccessioniPrimary (citable) accession number: A6NCD4
Secondary accession number(s): B1AMZ2, B4DG41
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 22, 2008
Last modified: July 9, 2014
This is version 49 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM

External Data

Dasty 3

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