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A6NCD4

- CJ131_HUMAN

UniProt

A6NCD4 - CJ131_HUMAN

Protein

Uncharacterized protein C10orf131

Gene

C10orf131

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
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    • Format
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 3 (22 Jul 2008)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C10orf131
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:31667. C10orf131.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134931868.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 256256Uncharacterized protein C10orf131PRO_0000320923Add
    BLAST

    Proteomic databases

    PaxDbiA6NCD4.
    PRIDEiA6NCD4.

    Expressioni

    Gene expression databases

    BgeeiA6NCD4.
    GenevestigatoriA6NCD4.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NCD4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili136 – 15924Sequence AnalysisAdd
    BLAST
    Coiled coili194 – 21421Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG255795.
    HOGENOMiHOG000111716.
    HOVERGENiHBG098298.
    InParanoidiA6NCD4.
    OrthoDBiEOG7X3QQ6.
    PhylomeDBiA6NCD4.
    TreeFamiTF333815.

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: A6NCD4-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSEEMDNITA EEIIDKHLQK DLDAEENQNV AKTLRGKVRE KLKISKINKG    50
    EKSSTEQLID SEIHQRSKLS PQTEVSLDES LSFFILSGEE GSALGKSSEQ 100
    RPVNRSYPKC FSLGVNLQNV AESEEEEFMK EFILTDILKV KAADYEDDQE 150
    QIKKQKANIF VPSSSPVVNQ RKLPKDMMPR ILEDEGFYIQ RKPEIYKKTC 200
    NKMENRLLKL EEAKCWFGES GEIMSLPTPI KQSWNFRLNV RKEPLNPLLK 250
    TIYRKL 256
    Length:256
    Mass (Da):29,615
    Last modified:July 22, 2008 - v3
    Checksum:i9418473D2366F675
    GO
    Isoform 2 (identifier: A6NCD4-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MGVQM
         167-256: VVNQRKLPKD...PLLKTIYRKL → GNILSQ

    Show »
    Length:176
    Mass (Da):19,808
    Checksum:i9765C52C1E321CD2
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 11M → MGVQM in isoform 2. 1 PublicationVSP_045322
    Alternative sequencei167 – 25690VVNQR…IYRKL → GNILSQ in isoform 2. 1 PublicationVSP_045323Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK294399 mRNA. Translation: BAG57652.1.
    AL513355, AL356155 Genomic DNA. Translation: CAH71690.1.
    AL356155, AL513355 Genomic DNA. Translation: CAI16400.1.
    CCDSiCCDS58090.1. [A6NCD4-2]
    RefSeqiNP_001123918.2. NM_001130446.2. [A6NCD4-2]
    UniGeneiHs.719076.

    Genome annotation databases

    EnsembliENST00000423344; ENSP00000411850; ENSG00000173088. [A6NCD4-2]
    GeneIDi100127889.
    KEGGihsa:100127889.
    UCSCiuc010qoo.2. human.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK294399 mRNA. Translation: BAG57652.1 .
    AL513355 , AL356155 Genomic DNA. Translation: CAH71690.1 .
    AL356155 , AL513355 Genomic DNA. Translation: CAI16400.1 .
    CCDSi CCDS58090.1. [A6NCD4-2 ]
    RefSeqi NP_001123918.2. NM_001130446.2. [A6NCD4-2 ]
    UniGenei Hs.719076.

    3D structure databases

    ProteinModelPortali A6NCD4.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi A6NCD4.
    PRIDEi A6NCD4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000423344 ; ENSP00000411850 ; ENSG00000173088 . [A6NCD4-2 ]
    GeneIDi 100127889.
    KEGGi hsa:100127889.
    UCSCi uc010qoo.2. human.

    Organism-specific databases

    CTDi 100127889.
    GeneCardsi GC10P097667.
    HGNCi HGNC:31667. C10orf131.
    neXtProti NX_A6NCD4.
    PharmGKBi PA134931868.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG255795.
    HOGENOMi HOG000111716.
    HOVERGENi HBG098298.
    InParanoidi A6NCD4.
    OrthoDBi EOG7X3QQ6.
    PhylomeDBi A6NCD4.
    TreeFami TF333815.

    Miscellaneous databases

    GenomeRNAii 100127889.
    NextBioi 20789158.

    Gene expression databases

    Bgeei A6NCD4.
    Genevestigatori A6NCD4.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Amygdala.
    2. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCJ131_HUMAN
    AccessioniPrimary (citable) accession number: A6NCD4
    Secondary accession number(s): B1AMZ2, B4DG41
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 50 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 10
      Human chromosome 10: entries, gene names and cross-references to MIM

    External Data

    Dasty 3