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Protein

Golgin subfamily A member 8I

Gene

GOLGA8I

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in maintaining Golgi structure.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 8I
Gene namesi
Name:GOLGA8I
Synonyms:GOLGA8IP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:26660. GOLGA8I.

Subcellular locationi

GO - Cellular componenti

  1. Golgi cisterna membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 632632Golgin subfamily A member 8IPRO_0000328760Add
BLAST

Proteomic databases

PRIDEiA6NC78.

PTM databases

PhosphoSiteiA6NC78.

Expressioni

Gene expression databases

BgeeiA6NC78.
GenevestigatoriA6NC78.

Organism-specific databases

HPAiHPA045397.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000399637.

Structurei

3D structure databases

ProteinModelPortaliA6NC78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni529 – 632104Golgi-targeting domainBy similarityAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili86 – 15469Sequence AnalysisAdd
BLAST
Coiled coili209 – 421213Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi629 – 6324Poly-Arg

Sequence similaritiesi

Belongs to the GOLGA8 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOVERGENiHBG051752.
InParanoidiA6NC78.
OMAiEGREAMS.
OrthoDBiEOG71P29T.
PhylomeDBiA6NC78.
TreeFamiTF316990.

Family and domain databases

InterProiIPR024858. Golgin_A.
[Graphical view]
PANTHERiPTHR10881. PTHR10881. 1 hit.

Sequencei

Sequence statusi: Complete.

A6NC78-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEETQHNKL AAAKKKLKEY WQKNSPRVPA GANRNRKTNG SIPQTATSGG
60 70 80 90 100
CQPPGDSATG FHREGPTSSA TLKDLESPCQ ERAVVLDSRS VEISQLKNTI
110 120 130 140 150
KSLKQQKKQV EHQLEEEKKA NIKKQKAKRV LEVQIQTLNI QKEELNTDLY
160 170 180 190 200
HMKRSLRYFE EKSKDLAVRL QHSLQRKGEL ESVLSDVMAT QKKKANQLSS
210 220 230 240 250
PSKAGTEWKL EQSMREEALL KVQLTQLKES FQQLQLERHE YAEHLKGERA
260 270 280 290 300
RWQQRMRKMS QEICTLKKEK QQDMRRVEKL ERSLSKLKNQ MAEPLPPEPP
310 320 330 340 350
AVPSEVELQH LRKELERVAG ALQAQVKNNQ RISLLNRGQE ERIREQEERL
360 370 380 390 400
RKQEERIQEQ HKSLQQLAKP QSVFEEPNNE NKSALQLEQQ VKELQEKLGE
410 420 430 440 450
EHLEAASQQN QQLTAQLSLM ALPGEGHGGE HLDSEGEEAP QPMPSVPEDL
460 470 480 490 500
ESREAMSSFM DHLEEKADLS ELVKKKELCF IHHWRERCHQ KTHHLLSEPG
510 520 530 540 550
GRAKDAALGG GHHQAGAQGG DEGEAAGAAA DGIAAYSNYN NGHRKFLAAA
560 570 580 590 600
HNPADEPGPG APAPQELGAA DKHGDLCEVS LTSSAQGEAR EDPLLDKPTA
610 620 630
QPIVQDHQEH PGLGSNCCVP FFCWAWLPRR RR
Length:632
Mass (Da):71,330
Last modified:January 15, 2008 - v2
Checksum:i1B88983B175FEA86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091565 Genomic DNA. No translation available.
UniGeneiHs.375441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091565 Genomic DNA. No translation available.
UniGeneiHs.375441.

3D structure databases

ProteinModelPortaliA6NC78.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000399637.

PTM databases

PhosphoSiteiA6NC78.

Proteomic databases

PRIDEiA6NC78.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiGC15P023906.
HGNCiHGNC:26660. GOLGA8I.
HPAiHPA045397.
neXtProtiNX_A6NC78.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG051752.
InParanoidiA6NC78.
OMAiEGREAMS.
OrthoDBiEOG71P29T.
PhylomeDBiA6NC78.
TreeFamiTF316990.

Gene expression databases

BgeeiA6NC78.
GenevestigatoriA6NC78.

Family and domain databases

InterProiIPR024858. Golgin_A.
[Graphical view]
PANTHERiPTHR10881. PTHR10881. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiGOG8I_HUMAN
AccessioniPrimary (citable) accession number: A6NC78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: January 15, 2008
Last modified: January 7, 2015
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.