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A6NC78

- GOG8I_HUMAN

UniProt

A6NC78 - GOG8I_HUMAN

Protein

Golgin subfamily A member 8I

Gene

GOLGA8I

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 2 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    May be involved in maintaining Golgi structure.By similarity

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Golgin subfamily A member 8I
    Gene namesi
    Name:GOLGA8I
    Synonyms:GOLGA8IP
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:26660. GOLGA8I.

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi cisterna membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 632632Golgin subfamily A member 8IPRO_0000328760Add
    BLAST

    Proteomic databases

    PRIDEiA6NC78.

    PTM databases

    PhosphoSiteiA6NC78.

    Expressioni

    Gene expression databases

    BgeeiA6NC78.
    GenevestigatoriA6NC78.

    Organism-specific databases

    HPAiHPA045397.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000399637.

    Structurei

    3D structure databases

    ProteinModelPortaliA6NC78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni529 – 632104Golgi-targeting domainBy similarityAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili86 – 15469Sequence AnalysisAdd
    BLAST
    Coiled coili209 – 421213Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi629 – 6324Poly-Arg

    Sequence similaritiesi

    Belongs to the GOLGA8 family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    HOVERGENiHBG051752.
    InParanoidiA6NC78.
    OMAiEGREAMS.
    OrthoDBiEOG71P29T.
    PhylomeDBiA6NC78.
    TreeFamiTF316990.

    Family and domain databases

    InterProiIPR024858. Golgin_A.
    [Graphical view]
    PANTHERiPTHR10881. PTHR10881. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6NC78-1 [UniParc]FASTAAdd to Basket

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    MAEETQHNKL AAAKKKLKEY WQKNSPRVPA GANRNRKTNG SIPQTATSGG    50
    CQPPGDSATG FHREGPTSSA TLKDLESPCQ ERAVVLDSRS VEISQLKNTI 100
    KSLKQQKKQV EHQLEEEKKA NIKKQKAKRV LEVQIQTLNI QKEELNTDLY 150
    HMKRSLRYFE EKSKDLAVRL QHSLQRKGEL ESVLSDVMAT QKKKANQLSS 200
    PSKAGTEWKL EQSMREEALL KVQLTQLKES FQQLQLERHE YAEHLKGERA 250
    RWQQRMRKMS QEICTLKKEK QQDMRRVEKL ERSLSKLKNQ MAEPLPPEPP 300
    AVPSEVELQH LRKELERVAG ALQAQVKNNQ RISLLNRGQE ERIREQEERL 350
    RKQEERIQEQ HKSLQQLAKP QSVFEEPNNE NKSALQLEQQ VKELQEKLGE 400
    EHLEAASQQN QQLTAQLSLM ALPGEGHGGE HLDSEGEEAP QPMPSVPEDL 450
    ESREAMSSFM DHLEEKADLS ELVKKKELCF IHHWRERCHQ KTHHLLSEPG 500
    GRAKDAALGG GHHQAGAQGG DEGEAAGAAA DGIAAYSNYN NGHRKFLAAA 550
    HNPADEPGPG APAPQELGAA DKHGDLCEVS LTSSAQGEAR EDPLLDKPTA 600
    QPIVQDHQEH PGLGSNCCVP FFCWAWLPRR RR 632
    Length:632
    Mass (Da):71,330
    Last modified:January 15, 2008 - v2
    Checksum:i1B88983B175FEA86
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC091565 Genomic DNA. No translation available.
    UniGeneiHs.375441.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC091565 Genomic DNA. No translation available.
    UniGenei Hs.375441.

    3D structure databases

    ProteinModelPortali A6NC78.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000399637.

    PTM databases

    PhosphoSitei A6NC78.

    Proteomic databases

    PRIDEi A6NC78.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    GeneCardsi GC15P023875.
    HGNCi HGNC:26660. GOLGA8I.
    HPAi HPA045397.
    neXtProti NX_A6NC78.
    GenAtlasi Search...

    Phylogenomic databases

    HOVERGENi HBG051752.
    InParanoidi A6NC78.
    OMAi EGREAMS.
    OrthoDBi EOG71P29T.
    PhylomeDBi A6NC78.
    TreeFami TF316990.

    Gene expression databases

    Bgeei A6NC78.
    Genevestigatori A6NC78.

    Family and domain databases

    InterProi IPR024858. Golgin_A.
    [Graphical view ]
    PANTHERi PTHR10881. PTHR10881. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
      Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
      , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
      Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiGOG8I_HUMAN
    AccessioniPrimary (citable) accession number: A6NC78
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 49 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3