A6NC78 (GOG8I_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Golgin subfamily A member 8I

Gene names

Name:	GOLGA8I
Synonyms:	GOLGA8IP

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	632 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be involved in maintaining Golgi structure By similarity.
Subcellular location	Golgi apparatus › Golgi stack membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the GOLGA8 family.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	Golgi cisterna membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 632	632	Golgin subfamily A member 8I		PRO_0000328760
Regions
	Region	529 – 632	104	Golgi-targeting domain By similarity
	Coiled coil	86 – 154	69	Potential
	Coiled coil	209 – 421	213	Potential
	Compositional bias	629 – 632	4	Poly-Arg

Sequences

	Sequence		Length	Mass (Da)
	A6NC78 [UniParc]. Last modified January 15, 2008. Version 2. Checksum: 1B88983B175FEA86	FASTA	632	71,330
	10 20 30 40 50 60 MAEETQHNKL AAAKKKLKEY WQKNSPRVPA GANRNRKTNG SIPQTATSGG CQPPGDSATG 70 80 90 100 110 120 FHREGPTSSA TLKDLESPCQ ERAVVLDSRS VEISQLKNTI KSLKQQKKQV EHQLEEEKKA 130 140 150 160 170 180 NIKKQKAKRV LEVQIQTLNI QKEELNTDLY HMKRSLRYFE EKSKDLAVRL QHSLQRKGEL 190 200 210 220 230 240 ESVLSDVMAT QKKKANQLSS PSKAGTEWKL EQSMREEALL KVQLTQLKES FQQLQLERHE 250 260 270 280 290 300 YAEHLKGERA RWQQRMRKMS QEICTLKKEK QQDMRRVEKL ERSLSKLKNQ MAEPLPPEPP 310 320 330 340 350 360 AVPSEVELQH LRKELERVAG ALQAQVKNNQ RISLLNRGQE ERIREQEERL RKQEERIQEQ 370 380 390 400 410 420 HKSLQQLAKP QSVFEEPNNE NKSALQLEQQ VKELQEKLGE EHLEAASQQN QQLTAQLSLM 430 440 450 460 470 480 ALPGEGHGGE HLDSEGEEAP QPMPSVPEDL ESREAMSSFM DHLEEKADLS ELVKKKELCF 490 500 510 520 530 540 IHHWRERCHQ KTHHLLSEPG GRAKDAALGG GHHQAGAQGG DEGEAAGAAA DGIAAYSNYN 550 560 570 580 590 600 NGHRKFLAAA HNPADEPGPG APAPQELGAA DKHGDLCEVS LTSSAQGEAR EDPLLDKPTA 610 620 630 QPIVQDHQEH PGLGSNCCVP FFCWAWLPRR RR

References

[1]

"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC091565 Genomic DNA. No translation available.
IPI	IPI00798221.
UniGene	Hs.375441.
3D structure databases
ProteinModelPortal	A6NC78.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000399637.
PTM databases
PhosphoSite	A6NC78.
Proteomic databases
PRIDE	A6NC78.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000450802; ENSP00000399637; ENSG00000153666.
Organism-specific databases
GeneCards	GC15P023811.
HGNC	HGNC:26660. GOLGA8I.
HPA	HPA045397.
neXtProt	NX_A6NC78.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG051752.
InParanoid	A6NC78.
OMA	ASEGCEG.
OrthoDB	EOG4CRM1Z.
Gene expression databases
Bgee	A6NC78.
Genevestigator	A6NC78.
Family and domain databases
InterPro	IPR024858. Golgin_A. [Graphical view]
PANTHER	PTHR10881. PTHR10881. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GOG8I_HUMAN

Accession

Primary (citable) accession number: A6NC78

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	January 15, 2008
Last modified:	April 3, 2013
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.